3ABI
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![BU of 3abi by Molmil](/molmil-images/mine/3abi) | Crystal Structure of L-Lysine Dehydrogenase from Hyperthermophilic Archaeon Pyrococcus horikoshii | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative uncharacterized protein PH1688, SULFATE ION | Authors: | Yoneda, K, Sakuraba, H, Fukuda, J, Ohshima, T. | Deposit date: | 2009-12-14 | Release date: | 2009-12-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | First crystal structure of L-lysine 6-dehydrogenase as an NAD-dependent amine dehydrogenase. J.Biol.Chem., 285, 2010
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2ZNR
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![BU of 2znr by Molmil](/molmil-images/mine/2znr) | Crystal structure of the DUB domain of human AMSH-LP | Descriptor: | 1,2-ETHANEDIOL, AMSH-like protease, PRASEODYMIUM ION, ... | Authors: | Sato, Y, Azusa, Y, Yamagata, A, Mimura, H, Wang, X, Yamashita, M, Ookata, K, Nureki, O, Iwai, K, Komada, M, Fukai, S. | Deposit date: | 2008-05-01 | Release date: | 2008-09-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains Nature, 455, 2008
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3A3O
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![BU of 3a3o by Molmil](/molmil-images/mine/3a3o) | Crystal structure of complex between SA-subtilisin and Tk-propeptide with deletion of the five C-terminal residues | Descriptor: | CALCIUM ION, Tk-subtilisin, ZINC ION | Authors: | Tanaka, S, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. | Deposit date: | 2009-06-15 | Release date: | 2009-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin J.Mol.Biol., 394, 2009
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2Z2Z
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![BU of 2z2z by Molmil](/molmil-images/mine/2z2z) | Crystal structure of unautoprocessed form of Tk-subtilisin soaked by 10mM CaCl2 | Descriptor: | CALCIUM ION, Tk-subtilisin precursor | Authors: | Tanaka, S, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. | Deposit date: | 2007-05-29 | Release date: | 2007-12-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Four new crystal structures of Tk-subtilisin in unautoprocessed, autoprocessed and mature forms: insight into structural changes during maturation J.Mol.Biol., 372, 2007
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2E1A
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![BU of 2e1a by Molmil](/molmil-images/mine/2e1a) | crystal structure of FFRP-DM1 | Descriptor: | 75aa long hypothetical regulatory protein AsnC, SELENOMETHIONINE | Authors: | Koike, H, Suzuki, M. | Deposit date: | 2006-10-19 | Release date: | 2007-09-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Structural Code for Discriminating between Transcription Signals Revealed by the Feast/Famine Regulatory Protein DM1 in Complex with Ligands Structure, 15, 2007
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6AHS
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![BU of 6ahs by Molmil](/molmil-images/mine/6ahs) | Mouse Kallikrein 7 in complex with imidazolinylindole derivative | Descriptor: | 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | Authors: | Sugawara, H. | Deposit date: | 2018-08-20 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors. Bioorg. Med. Chem. Lett., 29, 2019
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5ZHS
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![BU of 5zhs by Molmil](/molmil-images/mine/5zhs) | Crystal structure of OsD14 in complex with covalently bound KK052 | Descriptor: | (4-phenylpiperazin-1-yl)(1H-1,2,3-triazol-1-yl)methanone, Strigolactone esterase D14 | Authors: | Hirabayashi, K, Miyakawa, T, Tanokura, M. | Deposit date: | 2018-03-13 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses. Mol Plant, 12, 2019
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5ZHT
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![BU of 5zht by Molmil](/molmil-images/mine/5zht) | Crystal structure of OsD14 in complex with covalently bound KK073 | Descriptor: | (1H-1,2,3-triazol-1-yl){4-[4-(trifluoromethyl)phenyl]piperazin-1-yl}methanone, Strigolactone esterase D14 | Authors: | Hirabayashi, K, Miyakawa, T, Tanokura, M. | Deposit date: | 2018-03-13 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.532 Å) | Cite: | Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses. Mol Plant, 12, 2019
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5ZHR
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![BU of 5zhr by Molmil](/molmil-images/mine/5zhr) | Crystal structure of OsD14 in complex with covalently bound KK094 | Descriptor: | (2,3-dihydro-1H-indol-1-yl)(1H-1,2,3-triazol-1-yl)methanone, Strigolactone esterase D14 | Authors: | Hirabayashi, K, Miyakawa, T, Tanokura, M. | Deposit date: | 2018-03-13 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Triazole Ureas Covalently Bind to Strigolactone Receptor and Antagonize Strigolactone Responses. Mol Plant, 12, 2019
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5B4O
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![BU of 5b4o by Molmil](/molmil-images/mine/5b4o) | Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14 | Descriptor: | 1,2-ETHANEDIOL, 2-pyridin-3-yl-1,3-benzothiazin-4-one, Macrophage migration inhibitory factor, ... | Authors: | Oki, H, Igaki, S, Moriya, Y, Hayano, Y, Habuka, N. | Deposit date: | 2016-04-07 | Release date: | 2016-04-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression Chem. Biol., 17, 2010
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3VXK
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![BU of 3vxk by Molmil](/molmil-images/mine/3vxk) | Crystal structure of OsD14 | Descriptor: | Dwarf 88 esterase | Authors: | Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M. | Deposit date: | 2012-09-18 | Release date: | 2013-09-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular mechanism of strigolactone perception by DWARF14 Nat Commun, 4, 2013
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3WIO
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![BU of 3wio by Molmil](/molmil-images/mine/3wio) | Crystal structure of OSD14 in complex with hydroxy D-ring | Descriptor: | (5R)-5-hydroxy-3-methylfuran-2(5H)-one, Probable strigolactone esterase D14 | Authors: | Xue, Y.-L, Miyakawa, T, Hou, F, Qin, H.-M, Tanokura, M. | Deposit date: | 2013-09-22 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular mechanism of strigolactone perception by DWARF14 Nat Commun, 4, 2013
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3B4X
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![BU of 3b4x by Molmil](/molmil-images/mine/3b4x) | |
5ZFI
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![BU of 5zfi by Molmil](/molmil-images/mine/5zfi) | Mouse kallikrein 7 in complex with 6-benzyl-1,4-diazepan-7-one derivative | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[(3Z,6R)-6-[(2,6-dichlorophenyl)methyl]-3-(dimethylhydrazinylidene)-7-oxo-1,4-diazepan-1-yl]-N-[3-(1-methyl-1H-pyrazol-4-yl)phenyl]acetamide, Kallikrein-7 | Authors: | Sugawara, H. | Deposit date: | 2018-03-06 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones. Bioorg. Med. Chem., 26, 2018
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5ZFH
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![BU of 5zfh by Molmil](/molmil-images/mine/5zfh) | Mouse Kallikrein 7 | Descriptor: | Kallikrein-7 | Authors: | Sugawara, H. | Deposit date: | 2018-03-06 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones. Bioorg. Med. Chem., 26, 2018
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5Y9L
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![BU of 5y9l by Molmil](/molmil-images/mine/5y9l) | Human kallikrein 7 in complex with 1,3,6-trisubstituted 1,4-diazepane-7-one | Descriptor: | 3-[2-[(3Z,6R)-6-[(5-chloranyl-2-methoxy-phenyl)methyl]-3-(dimethylhydrazinylidene)-7-oxidanylidene-1,4-diazepan-1-yl]ethanoylamino]benzoic acid, CHLORIDE ION, Kallikrein-7 | Authors: | Sugawara, H. | Deposit date: | 2017-08-25 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors Bioorg. Med. Chem. Lett., 27, 2017
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5YJK
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![BU of 5yjk by Molmil](/molmil-images/mine/5yjk) | Human kallikrein 7 in complex with 1,4-diazepane-7-one 1-acetamide derivative | Descriptor: | (R)-2-(6-(5-chloro-2-methoxybenzyl)-3-(2,2-dimethylhydrazono)-7-oxo-1,4-diazepan-1-yl)-N-(3-(methylsulfonyl)phenyl)acetamide, CHLORIDE ION, Kallikrein-7 | Authors: | Sugawara, H. | Deposit date: | 2017-10-11 | Release date: | 2017-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors Bioorg. Med. Chem. Lett., 27, 2017
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2Z4P
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![BU of 2z4p by Molmil](/molmil-images/mine/2z4p) | Crystal structure of FFRP-DM1 | Descriptor: | 75aa long hypothetical regulatory protein AsnC, ISOLEUCINE | Authors: | Yamada, M, Koike, H, Kudo, N, Suzuki, M. | Deposit date: | 2007-06-21 | Release date: | 2007-09-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Structural Code for Discriminating between Transcription Signals Revealed by the Feast/Famine Regulatory Protein DM1 in Complex with Ligands Structure, 15, 2007
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3A7D
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![BU of 3a7d by Molmil](/molmil-images/mine/3a7d) | Crystal Structures of rat Catechol-O-Methyltransferase complexed with new bi-substrate type inhibitor | Descriptor: | 5'-deoxy-5'-[4-({[(2,3-dihydroxy-5-nitrophenyl)carbonyl]amino}methyl)-1H-1,2,3-triazol-1-yl]adenosine, Catechol O-methyltransferase, MAGNESIUM ION, ... | Authors: | Tsuji, E. | Deposit date: | 2009-09-26 | Release date: | 2010-09-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Hit to Lead: Comprehensive Strategy of de novo Scaffold Generation by FBDD. Part 2: Ligand Fishing using Mass Spectrometry by Detection of Ligand-Protein Non-Covalent Complex after Matrix Click Chemistry To be Published
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4FXC
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![BU of 4fxc by Molmil](/molmil-images/mine/4fxc) | |
1DJU
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![BU of 1dju by Molmil](/molmil-images/mine/1dju) | CRYSTAL STRUCTURE OF AROMATIC AMINOTRANSFERASE FROM PYROCOCCUS HORIKOSHII OT3 | Descriptor: | AROMATIC AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Matsui, I, Matsui, E, Sakai, Y, Kikuchi, H, Kawarabayashi, H. | Deposit date: | 1999-12-06 | Release date: | 2001-04-11 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The molecular structure of hyperthermostable aromatic aminotransferase with novel substrate specificity from Pyrococcus horikoshii. J.Biol.Chem., 275, 2000
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8RKI
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![BU of 8rki by Molmil](/molmil-images/mine/8rki) | Molecular basis of ZP3/ZP1 heteropolymerization: crystal structure of a native vertebrate egg coat filament fragment | Descriptor: | Choriogenin H, YTTERBIUM (III) ION, Zona pellucida sperm-binding protein 3, ... | Authors: | Wiseman, B, Zamora-Caballero, S, de Sanctis, D, Yasumasu, S, Jovine, L. | Deposit date: | 2023-12-25 | Release date: | 2024-03-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell, 187, 2024
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2D3G
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![BU of 2d3g by Molmil](/molmil-images/mine/2d3g) | Double sided ubiquitin binding of Hrs-UIM | Descriptor: | ubiquitin, ubiquitin interacting motif from hepatocyte growth factor-regulated tyrosine kinase substrate | Authors: | Hirano, S, Kawasaki, M, Kato, R, Wakatsuki, S. | Deposit date: | 2005-09-28 | Release date: | 2005-12-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting Nat.Struct.Mol.Biol., 13, 2006
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4NBE
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![BU of 4nbe by Molmil](/molmil-images/mine/4nbe) | Fluorene-bound oxygenase with Phe275 replaced by Trp and ferredoxin complex of carbazole 1,9a-dioxygenase (form2) | Descriptor: | 9H-fluorene, FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Ashikawa, Y, Usami, Y, Inoue, K, Nojiri, H. | Deposit date: | 2013-10-23 | Release date: | 2014-03-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of the divergent oxygenation reactions catalyzed by the rieske nonheme iron oxygenase carbazole 1,9a-dioxygenase. Appl.Environ.Microbiol., 80, 2014
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4NB8
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![BU of 4nb8 by Molmil](/molmil-images/mine/4nb8) | Oxygenase with Ile262 replaced by Leu and ferredoxin complex of carbazole 1,9a-dioxygenase | Descriptor: | FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin CarAc, ... | Authors: | Ashikawa, Y, Usami, Y, Inoue, K, Nojiri, H. | Deposit date: | 2013-10-23 | Release date: | 2014-03-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural basis of the divergent oxygenation reactions catalyzed by the rieske nonheme iron oxygenase carbazole 1,9a-dioxygenase. Appl.Environ.Microbiol., 80, 2014
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