3DXZ
 
 | | Crystal structure of EcTrmB in complex with SAH | | Descriptor: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | Authors: | Zhou, H.H, Liu, Q, Gao, Y.X, Teng, M.K, Niu, L.W. | | Deposit date: | 2008-07-25 | | Release date: | 2009-05-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Proteins, 76, 2009
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3DXY
 | | Crystal structure of EcTrmB in complex with SAM | | Descriptor: | GLYCEROL, S-ADENOSYLMETHIONINE, SULFATE ION, ... | | Authors: | Zhou, H.H, Liu, Q, Gao, Y.X, Teng, M.K, Niu, L.W. | | Deposit date: | 2008-07-25 | | Release date: | 2009-05-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Proteins, 76, 2009
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6LRB
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6LJB
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7KPT
 | | Crystal structure of CtdE in complex with FAD and substrate 4 | | Descriptor: | (6aR,7aS,11S,13aS)-6,6,11-trimethyl-4-(3-methylbut-2-en-1-yl)-6,6a,7,8,9,10,11,14-octahydro-5H,13H-13a,7a-(epiminomethano)quinolizino[2,3-b]carbazol-16-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | Authors: | Zhao, B, Hu, L. | | Deposit date: | 2020-11-12 | | Release date: | 2021-06-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins.
Nat Commun, 12, 2021
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7KPQ
 | | Crystal structure of CtdE in complex with FAD | | Descriptor: | FAD-dependent monooxygenase CtdE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Zhao, B, Hu, L. | | Deposit date: | 2020-11-12 | | Release date: | 2021-06-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins.
Nat Commun, 12, 2021
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8IQC
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8IQI
 | | Structure of Full-Length AsfvPrimPol in Complex-Form | | Descriptor: | DNA (32-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Shao, Z.W, Su, S.C, Gan, J.H. | | Deposit date: | 2023-03-16 | | Release date: | 2023-07-26 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structures and implications of the C962R protein of African swine fever virus.
Nucleic Acids Res., 51, 2023
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8IQH
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8IQB
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8IQD
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4R5Y
 | | The complex structure of Braf V600E kinase domain with a novel Braf inhibitor | | Descriptor: | 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf | | Authors: | Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M. | | Deposit date: | 2014-08-22 | | Release date: | 2016-02-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Mol.Cancer Ther., 14, 2015
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8XJ8
 | | The Cryo-EM structure of MPXV E5 C-terminal in complex with DNA | | Descriptor: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | | Authors: | Zhang, W, Liu, Y, Gao, H, Gan, J. | | Deposit date: | 2023-12-20 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
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8XJ7
 | | The Cryo-EM structure of MPXV E5 in complex with DNA | | Descriptor: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | | Authors: | Zhang, W, Liu, Y, Gao, H, Gan, J. | | Deposit date: | 2023-12-20 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
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8XJ6
 | | The Cryo-EM structure of MPXV E5 apo conformation | | Descriptor: | AMP PHOSPHORAMIDATE, Monkeypox virus E5, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Zhang, W, Liu, Y, Gao, H, Gan, J. | | Deposit date: | 2023-12-20 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
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2M8V
 | | Solution Structure and Activity Study of Bovicin HJ50, a Particular Type AII Lantibiotic | | Descriptor: | BovA | | Authors: | Zhang, J, Feng, Y, Wang, J, Zhong, J. | | Deposit date: | 2013-05-29 | | Release date: | 2014-05-21 | | Last modified: | 2024-07-10 | | Method: | SOLUTION NMR | | Cite: | Type AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of action.
Biochem.J., 461, 2014
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3NMX
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-22 | | Release date: | 2011-07-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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6M63
 | | Crystal structure of a cAMP sensor G-Flamp1. | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Chimera of Cyclic nucleotide-gated potassium channel mll3241 and Yellow fluorescent protein | | Authors: | Zhou, Z, Chen, S, Wang, L, Chu, J. | | Deposit date: | 2020-03-12 | | Release date: | 2021-09-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.
Nat Commun, 13, 2022
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3NMZ
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-23 | | Release date: | 2011-07-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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3NMW
 | | Crystal structure of armadillo repeats domain of APC | | Descriptor: | APC variant protein, SULFATE ION | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-22 | | Release date: | 2011-07-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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6L8N
 | | Crystal structure of the K. lactis Rad5 | | Descriptor: | DNA repair protein RAD5, ZINC ION | | Authors: | Shen, M, Xiang, S. | | Deposit date: | 2019-11-06 | | Release date: | 2020-11-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural basis for the multi-activity factor Rad5 in replication stress tolerance.
Nat Commun, 12, 2021
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8WKS
 | | Cryo-EM structure of DSR2-TUBE complex | | Descriptor: | SIR2-like domain-containing protein, TUBE | | Authors: | Gao, A, Huang, J, Zhu, K. | | Deposit date: | 2023-09-28 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
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8WKX
 | | Cryo-EM structure of DSR2 | | Descriptor: | SIR2-like domain-containing protein | | Authors: | Gao, A, Huang, J, Zhu, K. | | Deposit date: | 2023-09-28 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.15 Å) | | Cite: | Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
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8WKT
 | | Cryo-EM structure of DSR2-DSAD1 complex | | Descriptor: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | | Authors: | Gao, A, Huang, J, Zhu, K. | | Deposit date: | 2023-09-28 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
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6M7P
 | | Human DNA polymerase eta extension complex with cdA at the -2 position | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*TP*GP*TP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*CP*(02I)P*CP*AP*CP*AP*CP*T)-3'), ... | | Authors: | Gregory, M.T, Yang, W. | | Deposit date: | 2018-08-20 | | Release date: | 2018-09-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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