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6W9T
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BU of 6w9t by Molmil
Crystal structure of Neisseria meningitidis ClpP protease complex with small molecule activator ACP1-06
Descriptor: ATP-dependent Clp protease proteolytic subunit, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide, POTASSIUM ION
Authors:Mabanglo, M.F, Houry, W.A.
Deposit date:2020-03-23
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Development of Antibiotics That Dysregulate the Neisserial ClpP Protease.
Acs Infect Dis., 6, 2020
9C6M
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BU of 9c6m by Molmil
Yasminevirus c12orf29, a 5' to 3' RNA ligase, K73M mutant
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RNA ligase1
Authors:Hu, Y, Lopez, V.A, Tagliabracci, V.S, Tomchick, D.R.
Deposit date:2024-06-07
Release date:2024-10-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation
To Be Published
9C6L
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BU of 9c6l by Molmil
Yasminevirus c12orf29, a 5' to 3' RNA ligase
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, RNA ligase1, ...
Authors:Hu, Y, Lopez, V.A, Tagliabracci, V.S, Tomchick, D.R.
Deposit date:2024-06-07
Release date:2024-10-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation
To Be Published
5Y41
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BU of 5y41 by Molmil
Crystal Structure of LIGAND-BOUND NURR1-LBD
Descriptor: (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Sreekanth, R, Lescar, J, Yoon, H.S.
Deposit date:2017-07-31
Release date:2018-12-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function.
Nat.Chem.Biol., 2020
7DFU
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BU of 7dfu by Molmil
Crystal structure of Xanthomonas oryzae ClpP S68Y in complex with ADEP4.
Descriptor: ATP-dependent Clp protease proteolytic subunit, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Yang, C.-G, Yang, T.
Deposit date:2020-11-09
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Dysregulation of ClpP by Small-Molecule Activators Used Against Xanthomonas oryzae pv. oryzae Infections.
J.Agric.Food Chem., 69, 2021
7DFT
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BU of 7dft by Molmil
Crystal structure of Xanthomonas oryzae ClpP
Descriptor: ATP-dependent Clp protease proteolytic subunit, CHLORIDE ION
Authors:Yang, C.-G, Yang, T.
Deposit date:2020-11-09
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dysregulation of ClpP by Small-Molecule Activators Used Against Xanthomonas oryzae pv. oryzae Infections.
J.Agric.Food Chem., 69, 2021
7X9P
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BU of 7x9p by Molmil
Crystal structure of human STING complexed with compound BSP17
Descriptor: 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein
Authors:Pan, L, Guan, X, Feng, X, Li, Z, Bian, J.
Deposit date:2022-03-15
Release date:2023-03-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of Selenium-containing STING agonists as orally available anti tumor agents
To be published
7X9Q
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BU of 7x9q by Molmil
Crystal structure of human STING complexed with compound BSP16
Descriptor: (2R)-4-(5,6-dimethoxy-1-benzoselenophen-2-yl)-2-ethyl-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein
Authors:Pan, L, Guan, X, Feng, X, Li, Z, Bian, J.
Deposit date:2022-03-15
Release date:2022-09-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor Agents.
J.Med.Chem., 65, 2022
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