8GF7
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![BU of 8gf7 by Molmil](/molmil-images/mine/8gf7) | Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein | Authors: | Balana, J.A, Nguyen, A.B, Saelices, L, Pratt, R.M. | Deposit date: | 2023-03-07 | Release date: | 2023-11-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | O-GlcNAc forces an alpha-synuclein amyloid strain with notably diminished seeding and pathology. Nat.Chem.Biol., 20, 2024
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8E7J
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![BU of 8e7j by Molmil](/molmil-images/mine/8e7j) | |
6SI7
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![BU of 6si7 by Molmil](/molmil-images/mine/6si7) | |
6N33
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![BU of 6n33 by Molmil](/molmil-images/mine/6n33) | Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622 | Descriptor: | 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor | Authors: | Zhang, Y. | Deposit date: | 2018-11-14 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun, 10, 2019
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3S36
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3S37
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![BU of 3s37 by Molmil](/molmil-images/mine/3s37) | |
3S34
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![BU of 3s34 by Molmil](/molmil-images/mine/3s34) | Structure of the 1121B Fab fragment | Descriptor: | 1121B Fab heavy chain, 1121B Fab light chain, PHOSPHATE ION | Authors: | Franklin, M.C. | Deposit date: | 2011-05-17 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies. Structure, 19, 2011
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3S35
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![BU of 3s35 by Molmil](/molmil-images/mine/3s35) | Structural basis for the function of two anti-VEGF receptor antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6.64 Fab heavy chain, ... | Authors: | Franklin, M.C. | Deposit date: | 2011-05-17 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies. Structure, 19, 2011
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6HZ6
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![BU of 6hz6 by Molmil](/molmil-images/mine/6hz6) | Structure of McrBC without DNA binding domains (Class 2) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
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6HZ4
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![BU of 6hz4 by Molmil](/molmil-images/mine/6hz4) | Structure of McrBC without DNA binding domains (one half of the full complex) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
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6HZ9
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![BU of 6hz9 by Molmil](/molmil-images/mine/6hz9) | Structure of McrBC without DNA binding domains (Class 5) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
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6HZ7
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![BU of 6hz7 by Molmil](/molmil-images/mine/6hz7) | Structure of McrBC without DNA binding domains (Class 3) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
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6HZ5
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![BU of 6hz5 by Molmil](/molmil-images/mine/6hz5) | Structure of McrBC without DNA binding domains (Class 1) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
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6HZ8
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![BU of 6hz8 by Molmil](/molmil-images/mine/6hz8) | Structure of McrBC without DNA binding domains (Class 4) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A. | Deposit date: | 2018-10-22 | Release date: | 2019-07-24 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC. Nat Commun, 10, 2019
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3A5U
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![BU of 3a5u by Molmil](/molmil-images/mine/3a5u) | Promiscuity and specificity in DNA binding to SSB: Insights from the structure of the Mycobacterium smegmatis SSB-ssDNA complex | Descriptor: | DNA (31-MER), Single-stranded DNA-binding protein | Authors: | Kaushal, P.S, Manjunath, G.P, Sekar, K, Muniyappa, K, Vijayan, M. | Deposit date: | 2009-08-12 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Promiscuity and specificity in DNA binding to SSB: Insights from the structure of the Mycobacterium smegmatis SSB-ssDNA complex. To be Published, 2009
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7VSR
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![BU of 7vsr by Molmil](/molmil-images/mine/7vsr) | Structure of McrBC (stalkless mutant) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Saikrishnan, K, Adhav, V.A, Bose, S, Kutti R, V. | Deposit date: | 2021-10-27 | Release date: | 2023-02-15 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of McrBC (stalkless mutant) To Be Published
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4MK0
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4L9I
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5A5C
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![BU of 5a5c by Molmil](/molmil-images/mine/5a5c) | Structure of an engineered neuronal LRRTM2 adhesion molecule | Descriptor: | LRRTM | Authors: | Paatero, A, Rosti, K, Shkumatov, A.V, Brunello, C, Kysenius, K, Huttunen, H, Kajander, T. | Deposit date: | 2015-06-17 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Crystal Structure of an Engineered Lrrtm2 Synaptic Adhesion Molecule and a Model for Neurexin Binding. Biochemistry, 55, 2016
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