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2NYN
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BU of 2nyn by Molmil
Crystal structure of phenylalanine ammonia-lyase from Anabaena variabilis
Descriptor: Phenylalanine/histidine ammonia-lyase
Authors:Louie, G.V, Moffitt, M.C, Bowman, M.E, Pence, J, Noel, J.P, Moore, B.S.
Deposit date:2006-11-21
Release date:2007-02-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
Biochemistry, 46, 2007
2O7D
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BU of 2o7d by Molmil
Tyrosine ammonia-lyase from Rhodobacter sphaeroides, complexed with caffeate
Descriptor: CAFFEIC ACID, Putative histidine ammonia-lyase
Authors:Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P.
Deposit date:2006-12-10
Release date:2007-01-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
2O7F
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BU of 2o7f by Molmil
Tyrosine ammonia-lyase from Rhodobacter sphaeroides (His89Phe variant), complexed with coumaric acid
Descriptor: 4'-HYDROXYCINNAMIC ACID, Putative histidine ammonia-lyase
Authors:Louie, G.V, Bowman, M.E, Moffitt, M.C, Baiga, T.J, Moore, B.S, Noel, J.P.
Deposit date:2006-12-11
Release date:2007-01-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
Chem.Biol., 13, 2006
1U0M
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BU of 1u0m by Molmil
Crystal Structure of 1,3,6,8-Tetrahydroxynaphthalene Synthase (THNS) from Streptomyces coelicolor A3(2): a Bacterial Type III Polyketide Synthase (PKS) Provides Insights into Enzymatic Control of Reactive Polyketide Intermediates
Descriptor: GLYCEROL, POLYETHYLENE GLYCOL (N=34), putative polyketide synthase
Authors:Austin, M.B, Izumikawa, M, Bowman, M.E, Udwary, D.W, Ferrer, J.L, Moore, B.S, Noel, J.P.
Deposit date:2004-07-13
Release date:2004-09-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates
J.Biol.Chem., 279, 2004
4XLO
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BU of 4xlo by Molmil
Crystal Structure of EncM (crystallized with 4 mM NADPH)
Descriptor: FAD-dependent oxygenase EncM, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Teufel, R.
Deposit date:2015-01-13
Release date:2015-01-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement.
Nature, 503, 2013
8TWN
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BU of 8twn by Molmil
Crystal structure of nitrile synthase AetD with substrate bound
Descriptor: (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, D-MALATE
Authors:Ye, N, Drennan, C.L.
Deposit date:2023-08-21
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Oxidative Rearrangement of tryptophan to indole nitrile by a single diiron enzyme
To Be Published
8TWT
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BU of 8twt by Molmil
Crystal structure of nitrile synthase AetD with substrate bound and cofactor partially assembled
Descriptor: (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, D-MALATE, ...
Authors:Ye, N, Drennan, C.L.
Deposit date:2023-08-21
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme
To Be Published
8TWW
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BU of 8tww by Molmil
Crystal structure of nitrile synthase AetD with substrate bound and cofactor fully assembled
Descriptor: (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, FE (III) ION
Authors:Ye, N, Drennan, C.L.
Deposit date:2023-08-21
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme
To Be Published
6CY8
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BU of 6cy8 by Molmil
Crystal structure of FAD-dependent dehydrogenase
Descriptor: 4'-PHOSPHOPANTETHEINE, Alpha/beta hydrolase fold protein, Butyryl-CoA dehydrogenase, ...
Authors:Agarwal, V.
Deposit date:2018-04-05
Release date:2019-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.729 Å)
Cite:Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein.
Biochemistry, 58, 2019
6CXT
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BU of 6cxt by Molmil
Crystal structure of FAD-dependent dehydrogenase
Descriptor: 1,2-ETHANEDIOL, Alpha/beta hydrolase fold protein, Butyryl-CoA dehydrogenase, ...
Authors:Agarwal, V.
Deposit date:2018-04-04
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein.
Biochemistry, 58, 2019
2WR8
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BU of 2wr8 by Molmil
Structure of Pyrococcus horikoshii SAM hydroxide adenosyltransferase in complex with SAH
Descriptor: PUTATIVE UNCHARACTERIZED PROTEIN PH0463, S-ADENOSYL-L-HOMOCYSTEINE
Authors:McMahon, S.A, Deng, H, O'Hagan, D, Johnson, K.A, Naismith, J.H.
Deposit date:2009-08-31
Release date:2009-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Mechanistic Insights Into Water Activation in Sam Hydroxide Adenosyltransferase (Duf-62).
Chembiochem, 10, 2009
4HNP
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BU of 4hnp by Molmil
Crystal structure of yeast 20S proteasome in complex with vinylketone carmaphycin analogue VNK1
Descriptor: N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylhept-1-en-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, ...
Authors:Trivella, D.B.B, Stein, M, Groll, M.
Deposit date:2012-10-20
Release date:2014-01-29
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4HRD
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BU of 4hrd by Molmil
Crystal structure of yeast 20S proteasome in complex with the natural product carmaphycin A
Descriptor: N-[(2S)-1-({(2S)-1-{[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]amino}-4-[(R)-methylsulfinyl]-1-oxobutan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]hexanamide, Proteasome component C1, Proteasome component C11, ...
Authors:Trivella, D.B.B, Stein, M, Groll, M.
Deposit date:2012-10-27
Release date:2014-01-29
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4HRC
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BU of 4hrc by Molmil
Crystal structure of yeast 20S proteasome in complex with epoxyketone carmaphycin analogue 3
Descriptor: N-hexanoyl-L-valyl-N~1~-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, Proteasome component C11, ...
Authors:Trivella, D.B.B, Stein, M, Groll, M.
Deposit date:2012-10-27
Release date:2014-01-29
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
4LTC
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BU of 4ltc by Molmil
Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6
Descriptor: N-hexanoyl-L-valyl-N~1~-[(4S,5S,6R)-5-hydroxy-2,6-dimethyloctan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
Authors:Stein, M, Trivella, D.B.B, Groll, M.
Deposit date:2013-07-23
Release date:2014-07-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
Chem.Biol., 21, 2014
6FY8
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BU of 6fy8 by Molmil
The crystal structure of EncM bromide soak
Descriptor: BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYA
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BU of 6fya by Molmil
The crystal structure of EncM under anaerobic conditions
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FOQ
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BU of 6foq by Molmil
The crystal structure of EncM complexed with dioxygen under 15 bar of oxygen pressure.
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-02-08
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.386 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYE
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BU of 6fye by Molmil
The crystal structure of EncM H138T mutant
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYF
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BU of 6fyf by Molmil
The crystal structure of EncM V135M mutant
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FP3
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BU of 6fp3 by Molmil
The crystal structure of EncM complexed with dioxygen under 5 bar of oxygen pressure.
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, OXYGEN MOLECULE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-02-09
Release date:2018-05-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.976 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FY9
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BU of 6fy9 by Molmil
The crystal structure of EncM complex with xenon under 15 bars Xe pressure
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM, XENON
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYD
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BU of 6fyd by Molmil
The crystal structure of EncM T139V mutant
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FYG
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BU of 6fyg by Molmil
The crystal structure of EncM V135T mutant
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Putative FAD-dependent oxygenase EncM
Authors:Saleem-Batcha, R, Teufel, R.
Deposit date:2018-03-11
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Enzymatic control of dioxygen binding and functionalization of the flavin cofactor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7JPJ
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BU of 7jpj by Molmil
Crystal Structure of the essential dimeric LYSA from Phaeodactylum tricornutum
Descriptor: D-LYSINE, Diaminopimelate decarboxylase, SULFATE ION
Authors:Fedorov, E, Belinski, V.A, Brunson, J.K, Almo, S.C, Dupont, C.L, Ghosh, A.
Deposit date:2020-08-08
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:The Phaeodactylum tricornutum diaminopimelate decarboxylase was acquired via horizontal gene transfer from bacteria and displays substrate promiscuity
Biorxiv, 2020

224572

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