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3KWW
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BU of 3kww by Molmil
Crystal structure of the 'restriction triad' mutant of HLA B*3508, beta-2-microglobulin and EBV peptide
Descriptor: ACETIC ACID, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Archbold, J.K, Tynan, F.E, Gras, S, Rossjohn, J.
Deposit date:2009-12-01
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
Proc.Natl.Acad.Sci.USA, 2010
3VCL
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BU of 3vcl by Molmil
Crystal Structure of HLA-B7 with the HCMV pp65 peptide RPHERNGFTVL
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Petersen, J, Rossjohn, J.
Deposit date:2012-01-04
Release date:2012-11-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The impact of a large and frequent deletion in the human TCR beta locus on antiviral immunity
J.Immunol., 188, 2012
4QRS
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BU of 4qrs by Molmil
Crystal Structure of HLA B*0801 in complex with ELK_IYM, ELKRKMIYM
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Twist, K.-A, Rossjohn, J.
Deposit date:2014-07-02
Release date:2014-12-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
4JQV
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BU of 4jqv by Molmil
HLA-B*18:01 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 173-180)
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
Deposit date:2013-03-20
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
2NT0
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BU of 2nt0 by Molmil
Acid-beta-glucosidase low pH, glycerol bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Glucosylceramidase, ...
Authors:Lieberman, R.L, Petsko, G.A, Ringe, D.
Deposit date:2006-11-06
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.
Nat.Chem.Biol., 3, 2007
4JQX
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BU of 4jqx by Molmil
HLA-B*44:03 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 169-180)
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
Deposit date:2013-03-20
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
2NT1
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BU of 2nt1 by Molmil
Structure of acid-beta-glucosidase at neutral pH
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, PHOSPHATE ION
Authors:Lieberman, R.L, Petsko, G.A, Ringe, D.
Deposit date:2006-11-06
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.
Nat.Chem.Biol., 3, 2007
2NSX
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BU of 2nsx by Molmil
Structure of acid-beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCEROL, ...
Authors:Lieberman, R.L, Petsko, G.A, Ringe, D.
Deposit date:2006-11-06
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease.
Nat.Chem.Biol., 3, 2007
4E1Z
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BU of 4e1z by Molmil
Structure of mouse Tyk-2 complexed to a 3-aminoindazole inhibitor
Descriptor: N-[5-(4-{[(3-chlorophenyl)sulfonyl]amino}phenyl)-1H-indazol-3-yl]furan-2-carboxamide, Non-receptor tyrosine-protein kinase TYK2
Authors:Argiriadi, M.A, Talanian, R.V, Borhani, D.W.
Deposit date:2012-03-07
Release date:2012-10-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Bmc Struct.Biol., 12, 2012
4E20
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BU of 4e20 by Molmil
Structure of mouse Tyk-2 complexed to a 3-aminoindazole inhibitor
Descriptor: N-[4-(3-amino-1H-indazol-5-yl)phenyl]-3-chlorobenzenesulfonamide, Non-receptor tyrosine-protein kinase TYK2
Authors:Argiriadi, M.A, Talanian, R.V, Borhani, D.W.
Deposit date:2012-03-07
Release date:2012-10-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Bmc Struct.Biol., 12, 2012
7LGD
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BU of 7lgd by Molmil
HLA-B*07:02 in complex with SARS-CoV-2 nucleocapsid peptide N105-113
Descriptor: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ...
Authors:Gras, S, Szeto, C, Chatzileontiadou, D.S.M.
Deposit date:2021-01-20
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Immunity, 54, 2021
7LGT
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BU of 7lgt by Molmil
HLA-B*07:02 in complex with 229E-derived coronavirus nucleocapsid peptide N75-83
Descriptor: BROMIDE ION, Beta-2-microglobulin, CHLORIDE ION, ...
Authors:Gras, S, Szeto, C, Chatzileontiadou, D.S.M.
Deposit date:2021-01-21
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Immunity, 54, 2021
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