3QWV
 
 | | Crystal structure of histone lysine methyltransferase SmyD2 in complex with the cofactor product AdoHcy | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 2, ZINC ION | | Authors: | Jiang, Y, Sirinupong, N, Brunzelle, J, Yang, Z. | | Deposit date: | 2011-02-28 | | Release date: | 2011-07-06 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain.
Plos One, 6, 2011
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8TEG
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8TEL
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8TEJ
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8TEH
 | | Cryo-EM structure of Arabidopsis thaliana Bor1 in lipid nanodiscs | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Boron transporter 1 | | Authors: | Jiang, Y, Jiang, J. | | Deposit date: | 2023-07-06 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structure of borate transporter Bor1 reveals a novel auto-inhibition mechanism for
the SLC4 family
To Be Published
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8TEI
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8TEM
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8TEN
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4LMM
 | | Crystal structure of NHERF1 PDZ1 domain complexed with the CXCR2 C-terminal tail in P21 space group | | Descriptor: | ACETIC ACID, CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | | Authors: | Jiang, Y, Lu, G, Wu, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. | | Deposit date: | 2013-07-10 | | Release date: | 2014-01-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
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4MPA
 | | Crystal structure of NHERF1-CXCR2 signaling complex in P21 space group | | Descriptor: | ACETIC ACID, CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, ... | | Authors: | Jiang, Y, Lu, G, Wu, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. | | Deposit date: | 2013-09-12 | | Release date: | 2014-01-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.097 Å) | | Cite: | New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping.
Plos One, 8, 2013
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4PQW
 | | Crystal Structure of Phospholipase C beta 3 in Complex with PDZ1 of NHERF1 | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | | Authors: | Jiang, Y, Wang, S, Holcomb, J, Trescott, L, Guan, X, Hou, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. | | Deposit date: | 2014-03-04 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Crystallographic analysis of NHERF1-PLC beta 3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer.
Biochem.Biophys.Res.Commun., 446, 2014
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5H1Y
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2L5F
 | | Solution structure of the tandem WW domains from HYPA/FBP11 | | Descriptor: | Pre-mRNA-processing factor 40 homolog A | | Authors: | Jiang, Y, Hu, H. | | Deposit date: | 2010-11-01 | | Release date: | 2011-05-11 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Interaction with polyglutamine expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA)
To be Published
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8HOO
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8HOT
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4O6F
 | | Structural Basis of Estrogen Receptor Alpha Methylation Mediated by Histone Methyltransferase SmyD2 | | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Estrogen receptor, N-lysine methyltransferase SMYD2, ... | | Authors: | Jiang, Y, Trescott, L, Holcomb, J, Brunzelle, J, Sirinupong, N, Shi, X, Yang, Z. | | Deposit date: | 2013-12-20 | | Release date: | 2014-03-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.822 Å) | | Cite: | Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014
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2LJ1
 | | The third SH3 domain of R85FL with ataxin-7 PRR | | Descriptor: | Sorbin and SH3 domain-containing protein 1 | | Authors: | Jiang, Y, Hu, H. | | Deposit date: | 2011-09-02 | | Release date: | 2012-09-05 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure Basis for the Recognition of Ataxin-7 PRR with R85FL SH3 Domain
To be Published
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2LJ0
 | | The third SH3 domain of R85FL | | Descriptor: | Sorbin and SH3 domain-containing protein 1 | | Authors: | Jiang, Y, Hu, H. | | Deposit date: | 2011-09-02 | | Release date: | 2012-09-05 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure Basis for the Recognition of Ataxin-7 PRR with R85FL SH3 Domain
To be Published
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8HGB
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8HGE
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8HGD
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5XJ1
 | | Crystal structure of spRlmCD | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | Authors: | Jiang, Y, Gong, Q. | | Deposit date: | 2017-04-28 | | Release date: | 2017-11-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.753 Å) | | Cite: | Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
PLoS ONE, 12, 2017
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5XJ2
 | | Structure of spRlmCD with U747 RNA | | Descriptor: | RNA (5'-R(*GP*GP*CP*AP*CP*GP*UP*GP*CP*U)-3'), S-ADENOSYL-L-HOMOCYSTEINE, Uncharacterized RNA methyltransferase SP_1029, ... | | Authors: | Jiang, Y, Gong, Q. | | Deposit date: | 2017-04-28 | | Release date: | 2017-11-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD
PLoS ONE, 12, 2017
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5X74
 | | The crystal Structure PDE delta in complex with compound (R, R)-1g | | Descriptor: | (2R)-2-(2-fluorophenyl)-3-[2-[4-[(2R)-2-(2-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]piperidin-1-yl]ethyl]-1,2-dihydroquinazolin-4-one, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | | Authors: | Jiang, Y, Zhuang, C, Chen, L, Wang, R, Wang, F, Sheng, C. | | Deposit date: | 2017-02-23 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
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5X73
 | | The crystal Structure PDE delta in complex with R-p9 | | Descriptor: | (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | | Authors: | Jiang, Y, Zhuang, C, Chen, L, Wang, R, Wang, F, Sheng, C. | | Deposit date: | 2017-02-23 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
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