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2QOG
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BU of 2qog by Molmil
Crotoxin B, the basic PLA2 from Crotalus durissus terrificus.
Descriptor: CALCIUM ION, Phospholipase A2 CB1, Phospholipase A2 CB2
Authors:Marchi-Salvador, D.P, Correa, L.C, Fontes, M.R.M.
Deposit date:2007-07-20
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.
Proteins, 72, 2008
3RZX
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BU of 3rzx by Molmil
Mouse importin alpha-Ku70 NLS peptide complex
Descriptor: Importin subunit alpha-2, Ku70 NLS peptide
Authors:Takeda, A.A.S, Fontes, M.R.M.
Deposit date:2011-05-12
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80.
J.Mol.Biol., 412, 2011
3RZ9
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BU of 3rz9 by Molmil
Mouse importin alpha-Ku80 NLS peptide complex
Descriptor: Importin subunit alpha-2, Ku80 NLS peptide
Authors:Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
Deposit date:2011-05-11
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80.
J.Mol.Biol., 412, 2011
3QNL
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BU of 3qnl by Molmil
Crystal structure of PrTX-I complexed to Rosmarinic Acid
Descriptor: (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ISOPROPYL ALCOHOL, ...
Authors:dos Santos, J.I, Fontes, M.R.M.
Deposit date:2011-02-08
Release date:2012-02-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition.
Plos One, 6, 2011
1PA0
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BU of 1pa0 by Molmil
CRYSTAL STRUCTURE OF BNSP-7, A LYS49-PHOSPHOLIPASE A2
Descriptor: Myotoxic phospholipase A2-like
Authors:Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.
Deposit date:2003-05-13
Release date:2004-07-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
4YZ7
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BU of 4yz7 by Molmil
Crystal structure of Piratoxin I (PrTX-I) complexed to aristolochic acid
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 9-HYDROXY ARISTOLOCHIC ACID, Basic phospholipase A2 homolog piratoxin-1, ...
Authors:Fernandes, C.A.H, Fontes, M.R.M.
Deposit date:2015-03-24
Release date:2015-08-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9589 Å)
Cite:Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids.
Plos One, 10, 2015
3HZD
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BU of 3hzd by Molmil
Crystal structure of bothropstoxin-I (BthTX-I), a PLA2 homologue from Bothrops jararacussu venom
Descriptor: LITHIUM ION, Phospholipase A2 homolog bothropstoxin-1
Authors:Silva, M.C.O, Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-23
Release date:2009-07-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3HZW
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BU of 3hzw by Molmil
Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB)
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
Authors:Fernandes, C.A.H, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-24
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I3I
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BU of 3i3i by Molmil
Crystal Structure of Bothropstoxin-I crystallized at 283 K
Descriptor: Phospholipase A2 homolog bothropstoxin-1
Authors:Salvador, G.H.M, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-30
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I03
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BU of 3i03 by Molmil
Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide
Authors:Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
Deposit date:2009-06-24
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3JR8
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BU of 3jr8 by Molmil
Crystal Structure of BthTX-II (Asp49-PLA2 from Bothrops jararacussu snake venom) with calcium ions
Descriptor: CALCIUM ION, Phospholipase A2 bothropstoxin-2
Authors:Borges, R.J, dos Santos, J.I, Fontes, M.R.M.
Deposit date:2009-09-08
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class.
Proteins, 79, 2011
5TFV
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BU of 5tfv by Molmil
Crystal Structure of MT-I isolated from Bothrops asper venom.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Basic phospholipase A2 myotoxin III
Authors:Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
Deposit date:2016-09-26
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".
Biochimie, 133, 2017
1DEA
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BU of 1dea by Molmil
STRUCTURE AND CATALYTIC MECHANISM OF GLUCOSAMINE 6-PHOSPHATE DEAMINASE FROM ESCHERICHIA COLI AT 2.1 ANGSTROMS RESOLUTION
Descriptor: GLUCOSAMINE 6-PHOSPHATE DEAMINASE, PHOSPHATE ION
Authors:Oliva, G, Fontes, M.R.M, Garratt, R.C, Altamirano, M.M, Calcagno, M.L, Horjales, E.
Deposit date:1995-09-13
Release date:1996-01-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution.
Structure, 3, 1995
1GOD
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BU of 1god by Molmil
MONOMERIC LYS-49 PHOSPHOLIPASE A2 HOMOLOGUE ISOLATED FROM THE VENOM OF CERROPHIDION (BOTHROPS) GODMANI
Descriptor: PROTEIN (PHOSPHOLIPASE A2)
Authors:Arni, R.K, Fontes, M.R.M, Barberato, C, Gutierrez, J.M, Diaz-Oreiro, C, Ward, R.J.
Deposit date:1999-04-16
Release date:1999-04-23
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of myotoxin II, a monomeric Lys49-phospholipase A2 homologue isolated from the venom of Cerrophidion (Bothrops) godmani.
Arch.Biochem.Biophys., 366, 1999
5U5P
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BU of 5u5p by Molmil
Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA mismatch repair protein Mlh1, Importin subunit alpha-1
Authors:Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R.
Deposit date:2016-12-07
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.171 Å)
Cite:DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Biochimie, 146, 2018
5U5R
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BU of 5u5r by Molmil
Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a PMS2 NLS Peptide
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Mismatch repair endonuclease PMS2
Authors:Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R.
Deposit date:2016-12-07
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway.
Biochimie, 146, 2018
2OK9
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BU of 2ok9 by Molmil
PrTX-I-BPB
Descriptor: ISOPROPYL ALCOHOL, Phospholipase A2 homolog 1, p-Bromophenacyl bromide
Authors:Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.
Deposit date:2007-01-16
Release date:2008-09-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of a phospholipase A(2) homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity.
Biochim.Biophys.Acta, 1794, 2009
2Q2J
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BU of 2q2j by Molmil
Crystal structure of PrTX-I, a PLA2 homolog from Bothrops pirajai
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phospholipase A2 homolog 1, SULFATE ION
Authors:dos Santos, J.I, Fontes, M.R.
Deposit date:2007-05-28
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site.
J.Struct.Biol., 167, 2009
1M05
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BU of 1m05 by Molmil
HLA B8 in complex with an Epstein Barr Virus determinant
Descriptor: Beta-2-microglobulin, CADMIUM ION, EBNA-3 nuclear protein, ...
Authors:Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, Fontes, M.R, McCluskey, J, Rossjohn, J.
Deposit date:2002-06-11
Release date:2003-09-02
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.
J.IMMUNOL., 169, 2003
1U73
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BU of 1u73 by Molmil
Crystal structure of a Dimeric Acidic Platelet Aggregation Inhibitor and Hypotensive Phospholipase A2 from Bothrops jararacussu
Descriptor: hypotensive phospholipase A2
Authors:Magro, A.J, Murakami, M.T, Soares, A.M, Arni, R.K, Fontes, M.R.
Deposit date:2004-08-02
Release date:2004-10-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) in the monomeric and dimeric states: insights into its oligomeric state
Biochem.Biophys.Res.Commun., 323, 2004
7TMX
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BU of 7tmx by Molmil
Structure of Mouse Importin alpha NEIL1 NLS Peptide Complex
Descriptor: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 1
Authors:Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
Deposit date:2022-01-20
Release date:2023-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
7TMY
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BU of 7tmy by Molmil
Structure of Mouse Importin alpha NEIL3 NLS Peptide Complex
Descriptor: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 3
Authors:Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
Deposit date:2022-01-20
Release date:2023-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
5VFM
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BU of 5vfm by Molmil
Crystal structure of BnSP-7 from Bothrops pauloensis complexed with p-coumaric acid
Descriptor: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, 4'-HYDROXYCINNAMIC ACID, Basic phospholipase A2 homolog BnSP-7, ...
Authors:De Lima, L.F.G, Fontes, M.R.M.
Deposit date:2017-04-08
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.058 Å)
Cite:Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
Biochimie, 142, 2017
5VFN
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BU of 5vfn by Molmil
Crystal structure of BnSP-7 from Bothrops pauloensis complexed with cinnamic acid
Descriptor: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, Basic phospholipase A2 homolog BnSP-7, HYDROCINNAMIC ACID, ...
Authors:De Lima, L.F.G, Fontes, M.R.M.
Deposit date:2017-04-08
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.389 Å)
Cite:Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
Biochimie, 142, 2017
5VFH
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BU of 5vfh by Molmil
Crystal structure of BnSP-7 from Bothrops pauloensis complexed to sulfates
Descriptor: Basic phospholipase A2 homolog BnSP-7, SULFATE ION
Authors:De Lima, L.F, Fontes, M.R.M.
Deposit date:2017-04-07
Release date:2017-12-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.592 Å)
Cite:Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
Biochimie, 142, 2017

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