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Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin.
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY HEAVY CHAIN, ...
Authors:	Voss, J.E, Vachieri, S.G, Gamblin, S.J, Collins, P.J, Haire, L.F, Skehel, J.J.
Deposit date:	2011-07-08
Release date:	2011-08-10
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.41 Å)
Cite:	A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins. Science, 333, 2011

8VQ9

Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:	Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2024-01-18
Release date:	2024-07-24
Method:	ELECTRON MICROSCOPY (2.7 Å)
Cite:	A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nat Commun, 15, 2024

8VQA

Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:	Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2024-01-18
Release date:	2024-07-24
Method:	ELECTRON MICROSCOPY (3.5 Å)
Cite:	A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nat Commun, 15, 2024

8VQB

Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:	Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2024-01-18
Release date:	2024-07-24
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nat Commun, 15, 2024

7OH1

Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1
Descriptor:	FAB TT110, Tetanus toxin
Authors:	Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:	2021-05-07
Release date:	2021-10-27
Last modified:	2021-11-24
Method:	ELECTRON MICROSCOPY (8 Å)
Cite:	Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice. J.Clin.Invest., 131, 2021

7OH0

Tetanus neurotoxin HC domain in complex with TT104-Fab1
Descriptor:	Fab TT104, Tetanus toxin
Authors:	Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:	2021-05-07
Release date:	2021-10-27
Last modified:	2021-11-24
Method:	ELECTRON MICROSCOPY (3.9 Å)
Cite:	Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice. J.Clin.Invest., 131, 2021

4RX4

Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
Authors:	Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
Deposit date:	2014-12-08
Release date:	2015-07-01
Last modified:	2021-06-02
Method:	X-RAY DIFFRACTION (3.45 Å)
Cite:	Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell(Cambridge,Mass.), 161, 2015

4RWY

Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:	Acharya, P, Luongo, T.S, Kwong, P.D.
Deposit date:	2014-12-08
Release date:	2015-07-01
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.128 Å)
Cite:	Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell(Cambridge,Mass.), 161, 2015

7TAS

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (local refinement of the RBD and S2K146)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, S2K146 Fab light chain, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-21
Release date:	2022-01-12
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022

7TAT

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2021-12-21
Release date:	2022-01-12
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022

7SOD

SARS-CoV-2 S NTD B.1.617.1 kappa variant S2L20 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOB

SARS-CoV-2 S B.1.617.1 kappa variant + S309 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (2.4 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SO9

SARS-CoV-2 S B.1.617.2 delta variant + S2M11 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (2.4 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOC

SARS-CoV-2 S RBD B.1.617.1 kappa variant S309 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, S309 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOE

SARS-CoV-2 S B.1.617.1 kappa variant + S2X303 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X303 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-06-08
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOF

SARS-CoV-2 S NTD B.1.617.1 kappa variant S2X303 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X303 Fab heavy chain, S2X303 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOA

SARS-CoV-2 S NTD B.1.617.2 delta variant + S2L20 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

8S9G

SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Fab Heavy chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2023-03-28
Release date:	2023-10-04
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Neutralization, effector function and immune imprinting of Omicron variants. Nature, 621, 2023

8G30

N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI19 Fab molecules
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FNI19 Fab heavy chain, ...
Authors:	Dang, H.V, Snell, G.
Deposit date:	2023-02-06
Release date:	2023-05-31
Last modified:	2023-06-28
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023

5OMZ

Solution structure of domain III (DIII)of Zika virus Envelope protein
Descriptor:	Envelope Protein
Authors:	Zerbe, O, Bardelli, M.
Deposit date:	2017-08-02
Release date:	2017-10-04
Last modified:	2024-06-19
Method:	SOLUTION NMR
Cite:	A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential. Cell, 171, 2017

8DYA

Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-08-03
Release date:	2022-11-30
Last modified:	2023-01-11
Method:	ELECTRON MICROSCOPY (3.67 Å)
Cite:	SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines. Sci Immunol, 7, 2022

8ERR

SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-10-12
Release date:	2022-10-26
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science, 378, 2022

8ERQ

SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-10-12
Release date:	2022-10-26
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science, 378, 2022

5Y0A

Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Descriptor:	protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
Authors:	Wang, J.Q, Lok, S.M.
Deposit date:	2017-07-15
Release date:	2017-10-04
Last modified:	2024-03-27
Method:	ELECTRON MICROSCOPY (22 Å)
Cite:	A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential. Cell, 171, 2017

8U0T

PRD-0038 RBD bound to Rhinolophus alcyone ACE2 (local refinement)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, PRD-0038, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-08-29
Release date:	2023-12-06
Last modified:	2023-12-27
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus. Cell Host Microbe, 31, 2023

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Displayed results:	25
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