7NVX
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![BU of 7nvx by Molmil](/molmil-images/mine/7nvx) | TFIIH in a post-translocated state (with ADP-BeF3) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NW0
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![BU of 7nw0 by Molmil](/molmil-images/mine/7nw0) | RNA polymerase II pre-initiation complex with open promoter DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVW
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![BU of 7nvw by Molmil](/molmil-images/mine/7nvw) | TFIIH in a pre-translocated state (without ADP-BeF3) | Descriptor: | CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription factor IIE subunit 1, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVZ
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![BU of 7nvz by Molmil](/molmil-images/mine/7nvz) | RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | Descriptor: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVS
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![BU of 7nvs by Molmil](/molmil-images/mine/7nvs) | RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVV
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![BU of 7nvv by Molmil](/molmil-images/mine/7nvv) | XPB-containing part of TFIIH in a post-translocated state (with ADP-BeF3) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, General transcription and DNA repair factor IIH helicase subunit XPB, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVY
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![BU of 7nvy by Molmil](/molmil-images/mine/7nvy) | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | Descriptor: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7OG4
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![BU of 7og4 by Molmil](/molmil-images/mine/7og4) | Human mitochondrial ribosome in complex with P/E-tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Aibara, S, Singh, V, Modelska, A, Amunts, A. | Deposit date: | 2021-05-06 | Release date: | 2021-06-23 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of mitochondrial translation. Elife, 9, 2020
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7OZN
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![BU of 7ozn by Molmil](/molmil-images/mine/7ozn) | RNA Polymerase II dimer (Class 1) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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7OZP
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![BU of 7ozp by Molmil](/molmil-images/mine/7ozp) | RNA Polymerase II dimer (Class 3) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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7OZO
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![BU of 7ozo by Molmil](/molmil-images/mine/7ozo) | RNA Polymerase II dimer (Class 2) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Aibara, S, Dienemann, C, Cramer, P. | Deposit date: | 2021-06-28 | Release date: | 2021-10-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
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5L3T
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![BU of 5l3t by Molmil](/molmil-images/mine/5l3t) | Structure of the Saccharomyces cerevisiae TREX-2 complex | Descriptor: | 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ... | Authors: | Stewart, M, Aibara, S. | Deposit date: | 2016-05-24 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (4.927 Å) | Cite: | The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region. J. Struct. Biol., 195, 2016
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4X2H
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![BU of 4x2h by Molmil](/molmil-images/mine/4x2h) | Sac3N peptide bound to Mex67:Mtr2 | Descriptor: | Putative mRNA export protein, Putative uncharacterized protein, SER-SER-VAL-PHE-GLY-ALA-PRO-ALA | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
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4X2O
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![BU of 4x2o by Molmil](/molmil-images/mine/4x2o) | Sac3N peptide bound to Mex67:Mtr2 | Descriptor: | Putative SAC3 family protein, Putative mRNA export protein, Putative uncharacterized protein | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
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5L2L
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![BU of 5l2l by Molmil](/molmil-images/mine/5l2l) | Nab2 Zn fingers 5-7 bound to A11G RNA | Descriptor: | Nab2p, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*G)-3'), ZINC ION | Authors: | Stewart, M, Aibara, S. | Deposit date: | 2016-08-02 | Release date: | 2016-12-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae. Nucleic Acids Res., 45, 2017
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7NVR
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![BU of 7nvr by Molmil](/molmil-images/mine/7nvr) | Human Mediator with RNA Polymerase II Pre-initiation complex | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Rengachari, S, Schilbach, S, Aibara, S, Cramer, P. | Deposit date: | 2021-03-15 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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6ERI
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![BU of 6eri by Molmil](/molmil-images/mine/6eri) | Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10 alpha, ... | Authors: | Perez Borema, A, Aibara, S, Paul, B, Tobiasson, V, Kimanius, D, Forsberg, B.O, Wallden, K, Lindahl, E, Amunts, A. | Deposit date: | 2017-10-18 | Release date: | 2018-04-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor. Nat Plants, 4, 2018
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5OOM
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![BU of 5oom by Molmil](/molmil-images/mine/5oom) | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | Deposit date: | 2017-08-08 | Release date: | 2017-09-13 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structures of the human mitochondrial ribosome in native states of assembly. Nat. Struct. Mol. Biol., 24, 2017
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5OOL
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![BU of 5ool by Molmil](/molmil-images/mine/5ool) | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | Deposit date: | 2017-08-08 | Release date: | 2017-09-13 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structures of the human mitochondrial ribosome in native states of assembly. Nat. Struct. Mol. Biol., 24, 2017
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5NGM
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![BU of 5ngm by Molmil](/molmil-images/mine/5ngm) | 2.9S structure of the 70S ribosome composing the S. aureus 100S complex | Descriptor: | 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Amunts, A, Yonath, A. | Deposit date: | 2017-03-18 | Release date: | 2017-10-04 | Last modified: | 2018-11-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus. Nat Commun, 8, 2017
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6I9R
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![BU of 6i9r by Molmil](/molmil-images/mine/6i9r) | Large subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristin | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Modelska, A, Aibara, S, Amunts, A. | Deposit date: | 2018-11-25 | Release date: | 2020-07-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep, 35, 2021
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2D3I
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![BU of 2d3i by Molmil](/molmil-images/mine/2d3i) | Crystal Structure of Aluminum-Bound Ovotransferrin at 2.15 Angstrom Resolution | Descriptor: | ALUMINUM ION, BICARBONATE ION, Ovotransferrin | Authors: | Mizutani, K, Mikami, B, Aibara, S, Hirose, M. | Deposit date: | 2005-09-28 | Release date: | 2005-11-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of aluminium-bound ovotransferrin at 2.15 Angstroms resolution. Acta Crystallogr.,Sect.D, 61, 2005
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6GL7
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![BU of 6gl7 by Molmil](/molmil-images/mine/6gl7) | Neurturin-GFRa2-RET extracellular complex | Descriptor: | GDNF family receptor alpha-2, Neurturin, Proto-oncogene tyrosine-protein kinase receptor Ret | Authors: | Bigalke, J.M, Aibara, S, Sandmark, J, Amunts, A. | Deposit date: | 2018-05-23 | Release date: | 2019-08-14 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain. Sci Adv, 5, 2019
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6FXC
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![BU of 6fxc by Molmil](/molmil-images/mine/6fxc) | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Kidmose, R, Amunts, A, Yonath, A. | Deposit date: | 2018-03-08 | Release date: | 2018-03-21 | Last modified: | 2018-11-21 | Method: | ELECTRON MICROSCOPY (6.76 Å) | Cite: | The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus. Nat Commun, 8, 2017
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5K9S
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![BU of 5k9s by Molmil](/molmil-images/mine/5k9s) | Importin-alpha in complex with HNF1-beta peptide | Descriptor: | HNF1 beta A splice variant 2, Importin subunit alpha-1 | Authors: | Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J. | Deposit date: | 2016-06-01 | Release date: | 2016-11-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Importin-alpha in complex with HNF1-beta peptide To Be Published
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