7VJQ
| Pectobacterium phage ZF40 apo-aca2 complexed with 26bp DNA substrate | Descriptor: | CHLORIDE ION, DNA (27-MER), GLYCEROL, ... | Authors: | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | Deposit date: | 2021-09-28 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2. J.Biol.Chem., 297, 2021
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7VJP
| Selenomethionine-derived Pectobacterium phage ZF40 apo-Aca2 | Descriptor: | SULFATE ION, anti-CRISPR-associated protein Aca2 | Authors: | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | Deposit date: | 2021-09-28 | Release date: | 2021-10-20 | Last modified: | 2022-02-02 | Method: | X-RAY DIFFRACTION (1.594 Å) | Cite: | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2. J.Biol.Chem., 297, 2021
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7VJO
| Pectobacterium phage ZF40 apo-Aca2 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, anti-CRISPR-associated protein Aca2 | Authors: | Liu, Y.H, Zhang, L.S, Wu, B.X, Huang, H.D. | Deposit date: | 2021-09-28 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2. J.Biol.Chem., 297, 2021
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7W5M
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6A52
| Oxidase ChaP-H1 | Descriptor: | FE (II) ION, dioxidase ChaP-H1 | Authors: | Zhang, B, Ge, H.M. | Deposit date: | 2018-06-21 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. J. Am. Chem. Soc., 140, 2018
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6A4X
| Oxidase ChaP-H2 | Descriptor: | Bleomycin resistance protein, FE (II) ION | Authors: | Zhang, B, Wang, Y.S, Ge, H.M. | Deposit date: | 2018-06-21 | Release date: | 2018-08-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. J. Am. Chem. Soc., 140, 2018
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6A4Z
| Oxidase ChaP | Descriptor: | ChaP protein, FE (II) ION | Authors: | Zhang, B, Ge, H.M. | Deposit date: | 2018-06-21 | Release date: | 2018-08-29 | Last modified: | 2018-09-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis. J. Am. Chem. Soc., 140, 2018
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2HX4
| Rat nNOS heme domain complexed with 4-N-(Nw-nitro-L-argininyl)-trans-4-hydroxyamino-L-proline amide | Descriptor: | (4R)-4-(HYDROXY{N~5~-[IMINO(NITROAMINO)METHYL]-L-ORNITHYL}AMINO)-L-PROLINAMIDE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Igarashi, J, Li, H, Poulos, T.L. | Deposit date: | 2006-08-02 | Release date: | 2007-04-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50, 2007
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2HX2
| Bovine eNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine | Descriptor: | (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)(HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Igarashi, J, Li, H, Poulos, T.L. | Deposit date: | 2006-08-02 | Release date: | 2007-04-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50, 2007
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2HX3
| Rat nNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine | Descriptor: | (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)(HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... | Authors: | Igarashi, J, Li, H, Poulos, T.L. | Deposit date: | 2006-08-02 | Release date: | 2007-04-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-Based Design and Synthesis of N(omega)-Nitro-l-Arginine-Containing Peptidomimetics as Selective Inhibitors of Neuronal Nitric Oxide Synthase. Displacement of the Heme Structural Water. J.Med.Chem., 50, 2007
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7DQZ
| Crystal structure of SARS 3C-like protease in apo form | Descriptor: | 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2020-12-24 | Release date: | 2021-09-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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7EO7
| Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.24916625 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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7EO8
| Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin | Descriptor: | 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase | Authors: | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | Deposit date: | 2021-04-21 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2808516 Å) | Cite: | Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus. J.Virol., 96, 2022
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5TVT
| Structure of Maternal Embryonic Leucine Zipper Kinase | Descriptor: | 9-(3,5-dichloro-4-hydroxyphenyl)-1-{trans-4-[(dimethylamino)methyl]cyclohexyl}-3-methyl-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-2(1H)-one, Maternal embryonic leucine zipper kinase | Authors: | Seo, H.-Y, Huang, H, Gray, N.S, Dhe-Paganon, S. | Deposit date: | 2016-11-10 | Release date: | 2017-11-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structure of Maternal Embryonic Leucine Zipper Kinase To Be Published
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7VCL
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7VCQ
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7VJN
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7XEX
| Crystal strucutre of apoCasDinG | Descriptor: | CasDinG | Authors: | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | Deposit date: | 2022-03-31 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XF0
| Crystal strucutre of CasDinG in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CasDinG | Authors: | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | Deposit date: | 2022-03-31 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XF1
| Crystal strucutre of apoCasDinG in complex with ssDNA | Descriptor: | CasDinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') | Authors: | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | Deposit date: | 2022-03-31 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XFZ
| CryoEM structure of type IV-A Csf-crRNAsp14-dsDNA ternary complex | Descriptor: | Csf1, Csf2, Csf3, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-04-02 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG1
| CryoEM structure of type IV-A Csf-crRNA binary complex | Descriptor: | Csf1, Csf2, Csf3, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-04-02 | Release date: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment Mol.Cell, 83, 2023
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7XG2
| CryoEM structure of type IV-A NTS-nicked dsDNA bound Csf-crRNA ternary complex | Descriptor: | Csf1, Csf2, Csf3, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-04-02 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG0
| CryoEM structure of type IV-A Csf-crRNA-dsDNA ternary complex | Descriptor: | Csf1, Csf2, Csf3, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-04-02 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG4
| CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex in a second state | Descriptor: | Csf1, Csf2, Csf3, ... | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | Deposit date: | 2022-04-02 | Release date: | 2023-08-09 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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