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7FHJ
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BU of 7fhj by Molmil
Crystal structure of BAZ2A with DNA
Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, DNA (5'-D(*CP*GP*GP*AP*AP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*TP*TP*CP*CP*G)-3'), ...
Authors:Liu, K, Dong, A, Li, Y, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2021-07-29
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.
J.Biol.Chem., 297, 2021
4REO
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BU of 4reo by Molmil
Mutant ribosomal protein l1 from thermus thermophilus with threonine 217 replaced by valine
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L1, GLYCINE, ...
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, Tishchenko, S.V, Nikonov, S.V.
Deposit date:2014-09-23
Release date:2015-03-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions.
Acta Crystallogr.,Sect.D, 71, 2015
3U4M
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BU of 3u4m by Molmil
Crystal structure of ribosomal protein tthl1 in complex with 80nt 23s rna from thermus thermophilus
Descriptor: 50S ribosomal protein L1, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, NIkonov, S.V.
Deposit date:2011-10-10
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution crystal structure of the isolated ribosomal L1 stalk.
Acta Crystallogr.,Sect.D, 68, 2012
4QGB
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BU of 4qgb by Molmil
Crystal structure of mutant ribosomal protein G219V TthL1
Descriptor: 50S ribosomal protein L1, ACETATE ION, CHLORIDE ION
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V.
Deposit date:2014-05-22
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions.
Acta Crystallogr.,Sect.D, 71, 2015
4QG3
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BU of 4qg3 by Molmil
Crystal structure of mutant ribosomal protein G219V TthL1 in complex with 80nt 23S RNA from Thermus thermophilus
Descriptor: 50S ribosomal protein L1, BETA-MERCAPTOETHANOL, ISOPROPYL ALCOHOL, ...
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V.
Deposit date:2014-05-22
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions.
Acta Crystallogr.,Sect.D, 71, 2015
4QVI
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BU of 4qvi by Molmil
Crystal structure of mutant ribosomal protein M218L TthL1 in complex with 80nt 23S RNA from Thermus thermophilus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 50S ribosomal protein L1, ACETATE ION, ...
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, NIkonov, S.V.
Deposit date:2014-07-15
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein-RNA affinity of ribosomal protein L1 mutants does not correlate with the number of intermolecular interactions.
Acta Crystallogr.,Sect.D, 71, 2015
6ZUE
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BU of 6zue by Molmil
Crystal structure of human DDB1 bound to human DCAF1 (amino acid residues 1046-1396)
Descriptor: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2020-07-22
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.094 Å)
Cite:Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.
Plos Pathog., 17, 2021
3TG8
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BU of 3tg8 by Molmil
Mutant ribosomal protein L1 lacking ala158 from thermus thermophilus
Descriptor: 50S ribosomal protein L1, CHLORIDE ION, TETRAETHYLENE GLYCOL
Authors:Gabdulkhakov, A.G, Nevskaya, N.A, Nikonov, S.V.
Deposit date:2011-08-17
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of interdomain mobility in ribosomal L1 proteins.
Acta Crystallogr.,Sect.D, 67, 2011
8K3L
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BU of 8k3l by Molmil
SOD1 and Nanobody3 complex
Descriptor: COPPER (II) ION, NB3, Superoxide dismutase [Cu-Zn], ...
Authors:Cheng, S, Liu, R, Ding, Y.
Deposit date:2023-07-16
Release date:2024-07-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:SOD1 and Nanobody1 complex
To Be Published
3KDU
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BU of 3kdu by Molmil
Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-((4-methylphenoxy)carbonyl)glycine
Descriptor: N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-[(4-methylphenoxy)carbonyl]glycine, Peroxisome proliferator-activated receptor alpha
Authors:Muckelbauer, J.K.
Deposit date:2009-10-23
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J.Med.Chem., 53, 2010
3KDT
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BU of 3kdt by Molmil
Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine
Descriptor: N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-(methoxycarbonyl)glycine, Peroxisome proliferator-activated receptor alpha
Authors:Muckelbauer, J.K.
Deposit date:2009-10-23
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J.Med.Chem., 53, 2010
7T79
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BU of 7t79 by Molmil
CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND AKA DIETHYL {[3-(3-{[5-(AZETIDINE-1-CARBON YL)PYRAZIN-2-YL]OXY}-5-(PROPAN-2-YLOXY)BENZAMIDO)-1H- PYRAZOL-1-YL]METHYL}PHOSPHONATE
Descriptor: Isoform 2 of Hexokinase-4, alpha-D-glucopyranose, diethyl {[3-(3-{[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy}-5-[(propan-2-yl)oxy]benzamido)-1H-pyrazol-1-yl]methyl}phosphonate
Authors:Muckelbauer, J.K.
Deposit date:2021-12-14
Release date:2022-03-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132).
J.Med.Chem., 65, 2022
7T78
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BU of 7t78 by Molmil
CRYSTAL STRUCTURE OF GLUCOKINASE (HEXOKINASE 4) COMPLEXED WITH LIGAND DIETHYL ({2-[3-(4-METHANESULFONYLPHENO XY)-5-{[(2S)-1-METHOXYPROPAN-2-YL]OXY}BENZAMIDO]-1,3-THIAZ OL-4-YL}METHYL)PHOSPHONATE
Descriptor: 1,2-ETHANEDIOL, Isoform 2 of Hexokinase-4, SODIUM ION, ...
Authors:Muckelbauer, J.K.
Deposit date:2021-12-14
Release date:2022-03-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1 H -pyrazol-1-yl)methyl)phosphonate (BMS-820132).
J.Med.Chem., 65, 2022
6E66
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BU of 6e66 by Molmil
Crystal structure of bacterial N-acetylglucosamine transferase NleB
Descriptor: 1,2-ETHANEDIOL, NleB
Authors:Yao, Q, Zheng, Y.Q, Shao, F.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6U4Y
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BU of 6u4y by Molmil
Crystal Structure of an EZH2-EED Complex in an Oligomeric State
Descriptor: Histone-lysine N-methyltransferase EZH2, Polycomb protein EED
Authors:Jiao, L, Liu, X.
Deposit date:2019-08-26
Release date:2020-07-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:A partially disordered region connects gene repression and activation functions of EZH2.
Proc.Natl.Acad.Sci.USA, 117, 2020
5IXJ
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BU of 5ixj by Molmil
Tryptophan Synthase beta-subunit from Pyrococcus furiosus with L-threonine non-covalently bound in the active site
Descriptor: SODIUM ION, THREONINE, Tryptophan synthase beta chain 1
Authors:Buller, A.R, Herger, M, Arnold, F.H.
Deposit date:2016-03-23
Release date:2016-08-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Synthesis of beta-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase.
J.Am.Chem.Soc., 138, 2016
6HPV
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BU of 6hpv by Molmil
Crystal structure of mouse fetuin-B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Fetuin-B
Authors:Fahrenkamp, D, Dietzel, E, de Sanctis, D, Jovine, L.
Deposit date:2018-09-22
Release date:2019-02-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.
Iucrj, 6, 2019
8DZI
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BU of 8dzi by Molmil
Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with one RBD down in complex with the Fab fragment of human neutralizing antibody MB.02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Hu, Y, Xiong, Y.
Deposit date:2022-08-07
Release date:2022-08-31
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
8DZH
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BU of 8dzh by Molmil
Structure of SARS-CoV-2 Omicron BA.1.1.529 Spike trimer with two RBDs down in complex with the Fab fragment of human neutralizing antibody MB.02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Hu, Y, Xiong, Y.
Deposit date:2022-08-07
Release date:2022-08-31
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Function and Cryo-EM structures of broadly potent bispecific antibodies against multiple SARS-CoV-2 Omicron sublineages.
Signal Transduct Target Ther, 8, 2023
3C0F
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BU of 3c0f by Molmil
Crystal Structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source
Descriptor: Uncharacterized protein AF_1514
Authors:Li, Y, Bahti, P, Shaw, N, Song, G, Yin, J, Zhu, J.-Y, Zhang, H, Xu, H, Wang, B.-C, Liu, Z.-J.
Deposit date:2008-01-20
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source.
Proteins, 71, 2008
8K5I
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BU of 8k5i by Molmil
The structure of SenA in complex with N,N,N-trimethyl-histidine and thioglucose
Descriptor: 1-thio-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, FE (III) ION, ...
Authors:Liu, M, Yang, Y, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-07-21
Release date:2023-12-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insights into a novel nonheme iron-dependent oxygenase in selenoneine biosynthesis.
Int.J.Biol.Macromol., 256, 2023
8K5J
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BU of 8k5j by Molmil
The structure of SenA in complex with N,N,N-trimethyl-histidine
Descriptor: FE (III) ION, GLYCEROL, N,N,N-trimethyl-histidine, ...
Authors:Liu, M, Yang, Y, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-07-21
Release date:2023-12-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural insights into a novel nonheme iron-dependent oxygenase in selenoneine biosynthesis.
Int.J.Biol.Macromol., 256, 2023
2MLK
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BU of 2mlk by Molmil
Three-dimensional structure of the C-terminal DNA-binding domain of RstA protein from Klebsiella pneumoniae
Descriptor: RstA
Authors:Fang, P, Chen, S, Cheng, Y, Chang, C, Yu, T, Huang, T.
Deposit date:2014-03-02
Release date:2014-07-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element.
Nucleic Acids Res., 42, 2014
2Q8Y
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BU of 2q8y by Molmil
Structural insight into the enzymatic mechanism of the phophothreonine lyase
Descriptor: 27.5 kDa virulence protein, Mitogen-activated protein kinase 7
Authors:Zhu, Y.-Q, Wang, D.-C, Shao, F.
Deposit date:2007-06-12
Release date:2007-12-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase
Mol.Cell, 28, 2007
2B1B
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BU of 2b1b by Molmil
5'-D(*GP*CP*GP*TP*GP*GP*GP*CP*AP*C)-3' Zif268 binding site
Descriptor: 5'-D(*GP*CP*GP*TP*GP*GP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*CP*CP*AP*CP*GP*C)-3', MAGNESIUM ION
Authors:Berman, H.M, Napoli, A.A.
Deposit date:2005-09-15
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Signatures of protein-DNA recognition in free DNA binding sites.
J.Mol.Biol., 386, 2009

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