4N8E
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![BU of 4n8e by Molmil](/molmil-images/mine/4n8e) | DPP4 complexed with compound 12a | Descriptor: | 1-[cis-4-(aminomethyl)-4-(3-chlorophenyl)cyclohexyl]piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | Authors: | Ostermann, N, Zink, F, Kroemer, M. | Deposit date: | 2013-10-17 | Release date: | 2014-02-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV. Bioorg.Med.Chem.Lett., 24, 2014
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5FVG
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![BU of 5fvg by Molmil](/molmil-images/mine/5fvg) | Structure of IrisFP at 100 K. | Descriptor: | Green to red photoconvertible GFP-like protein EosFP, SULFATE ION | Authors: | Colletier, J.P, Gallat, F.X, Coquelle, N, Weik, M. | Deposit date: | 2016-02-07 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein Irisfp. J.Phys.Chem.Lett, 7, 2016
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6Q8R
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6Q8Q
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6QAR
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5FVI
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![BU of 5fvi by Molmil](/molmil-images/mine/5fvi) | Structure of IrisFP in mineral grease at 100 K. | Descriptor: | Green to red photoconvertible GFP-like protein EosFP, SULFATE ION | Authors: | Colletier, J.P, Gallat, F.X, Coquelle, N, Weik, M. | Deposit date: | 2016-02-07 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein Irisfp. J.Phys.Chem.Lett., 7, 2016
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3M9Y
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![BU of 3m9y by Molmil](/molmil-images/mine/3m9y) | Crystal structure of Triosephosphate isomerase from methicillin resistant Staphylococcus aureus at 1.9 Angstrom resolution | Descriptor: | CITRIC ACID, SODIUM ION, Triosephosphate isomerase | Authors: | Mukherjee, S, Dutta, D, Saha, B, Das, A.K. | Deposit date: | 2010-03-23 | Release date: | 2011-04-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop Biochimie, 94, 2012
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4N8D
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![BU of 4n8d by Molmil](/molmil-images/mine/4n8d) | DPP4 complexed with syn-7aa | Descriptor: | 1-(cis-1-phenyl-4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}cyclohexyl)methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | Authors: | Ostermann, N, Zink, F, Kroemer, M. | Deposit date: | 2013-10-17 | Release date: | 2014-02-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV. Bioorg.Med.Chem.Lett., 24, 2014
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4FW8
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![BU of 4fw8 by Molmil](/molmil-images/mine/4fw8) | Crystal structure of FABG4 complexed with Coenzyme NADH | Descriptor: | (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-oxoacyl-(Acyl-carrier-protein) reductase | Authors: | Dutta, D, Bhattacharyya, S, Das, A.K. | Deposit date: | 2012-06-30 | Release date: | 2012-11-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal structure of hexanoyl-CoA bound to beta-ketoacyl reductase FabG4 of Mycobacterium tuberculosis Biochem.J., 450, 2013
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4H35
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4D17
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![BU of 4d17 by Molmil](/molmil-images/mine/4d17) | Crystal structure of cofactor-free urate oxidase in complex with its 5-peroxoisourate intermediate (X-ray dose, 106 kGy) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(HYDRO)PEROXOISOURATE, OXYGEN MOLECULE, ... | Authors: | Bui, S, Steiner, R.A. | Deposit date: | 2014-05-01 | Release date: | 2014-11-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4CW3
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![BU of 4cw3 by Molmil](/molmil-images/mine/4cw3) | Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 665 kGy) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, 9-METHYL URIC ACID, ... | Authors: | Bui, S, Steiner, R.A. | Deposit date: | 2014-04-01 | Release date: | 2014-10-29 | Last modified: | 2018-02-21 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4CW6
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![BU of 4cw6 by Molmil](/molmil-images/mine/4cw6) | Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 92 kGy) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, 9-METHYL URIC ACID, ... | Authors: | Bui, S, Steiner, R.A. | Deposit date: | 2014-04-01 | Release date: | 2014-10-29 | Last modified: | 2018-02-21 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4D12
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4CW0
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4D13
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4CW2
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![BU of 4cw2 by Molmil](/molmil-images/mine/4cw2) | Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 2.5 kGy) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, URICASE | Authors: | Bui, S, Steiner, R.A. | Deposit date: | 2014-04-01 | Release date: | 2014-10-29 | Last modified: | 2018-02-21 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4D19
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![BU of 4d19 by Molmil](/molmil-images/mine/4d19) | Crystal structure of cofactor-free urate oxidase in complex with its 5-peroxoisourate intermediate (X-ray dose, 1.75 MGy) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(HYDRO)PEROXOISOURATE, OXYGEN MOLECULE, ... | Authors: | Bui, S, Steiner, R.A. | Deposit date: | 2014-05-01 | Release date: | 2014-10-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4P78
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![BU of 4p78 by Molmil](/molmil-images/mine/4p78) | HicA3 and HicB3 toxin-antitoxin complex | Descriptor: | GLYCEROL, HicA3 Toxin, HicB3 antitoxin | Authors: | Li de la Sierra-Gallay, I, Bibi-Triki, S, van Tilbeurgh, H, Lazar, N, Pradel, E. | Deposit date: | 2014-03-26 | Release date: | 2014-08-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Functional and Structural Analysis of HicA3-HicB3, a Novel Toxin-Antitoxin System of Yersinia pestis. J.Bacteriol., 196, 2014
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4P7D
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![BU of 4p7d by Molmil](/molmil-images/mine/4p7d) | Antitoxin HicB3 crystal structure | Descriptor: | Antitoxin HicB3, CHLORIDE ION | Authors: | Li de la Sierra-Gallay, I, Bibi-Triki, S, van Tilbeurgh, H, Lazar, N, Pradel, E. | Deposit date: | 2014-03-27 | Release date: | 2014-08-27 | Last modified: | 2015-02-04 | Method: | X-RAY DIFFRACTION (2.781 Å) | Cite: | Functional and Structural Analysis of HicA3-HicB3, a Novel Toxin-Antitoxin System of Yersinia pestis. J.Bacteriol., 196, 2014
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2QPQ
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![BU of 2qpq by Molmil](/molmil-images/mine/2qpq) | Structure of Bug27 from Bordetella pertussis | Descriptor: | CITRIC ACID, protein Bug27 | Authors: | Herrou, J, Bompard, C. | Deposit date: | 2007-07-25 | Release date: | 2007-08-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structure-based mechanism of ligand binding for periplasmic solute-binding protein of the Bug family. J.Mol.Biol., 373, 2007
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6IC1
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![BU of 6ic1 by Molmil](/molmil-images/mine/6ic1) | urate oxidase under 90 bar of krypton | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-12-01 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6IA3
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![BU of 6ia3 by Molmil](/molmil-images/mine/6ia3) | urate oxidase under 220 bar (22 MPa) of argon | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ARGON, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-11-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6GCB
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6IA1
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![BU of 6ia1 by Molmil](/molmil-images/mine/6ia1) | urate oxidase under 120 bar of argon | Descriptor: | 8-AZAXANTHINE, ACETATE ION, ARGON, ... | Authors: | Prange, T, Colloc'h, N, Carpentier, P. | Deposit date: | 2018-11-26 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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