4CW2

Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 2.5 kGy)

Summary for 4CW2

Entry DOI	10.2210/pdb4cw2/pdb
Related	4CW0 4CW3 4CW6
Descriptor	URICASE, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
Functional Keywords	oxidoreductase, cofactor-free oxidase
Biological source	ASPERGILLUS FLAVUS
Cellular location	Peroxisome: Q00511
Total number of polymer chains	1
Total formula weight	34531.90
Authors	Bui, S.,Steiner, R.A. (deposition date: 2014-04-01, release date: 2014-10-29, Last modification date: 2018-02-21)
Primary citation	Bui, S.,von Stetten, D.,Jambrina, P.G.,Prange, T.,Colloc'h, N.,de Sanctis, D.,Royant, A.,Rosta, E.,Steiner, R.A. Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53:13710-13714, 2014 Cited by PubMed: 25314114 DOI: 10.1002/anie.201405485 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.32 Å)

Structure validation