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7XDH
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BU of 7xdh by Molmil
Crystal structure of a dimeric interlocked parallel G-quadruplex
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*GP*T)-3'), POTASSIUM ION
Authors:Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
Deposit date:2022-03-27
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
5SZR
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BU of 5szr by Molmil
Protocadherin Gamma B2 extracellular cadherin domains 3-6
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goodman, K.M, Mannepalli, S, Bahna, F, Rubinstein, R, Honig, B, Shapiro, L.
Deposit date:2016-08-14
Release date:2016-10-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:gamma-Protocadherin structural diversity and functional implications.
Elife, 5, 2016
5SZM
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BU of 5szm by Molmil
Protocadherin gamma A8 extracellular cadherin domains 1-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PcdhgA8 or protocadherin gamma A8, ...
Authors:Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L.
Deposit date:2016-08-14
Release date:2016-10-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:gamma-Protocadherin structural diversity and functional implications.
Elife, 5, 2016
5SZL
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BU of 5szl by Molmil
Protocadherin gamma A1 extracellular cadherin domains 1-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goodman, K.M, Bahna, F, Mannepalli, S, Honig, B, Shapiro, L.
Deposit date:2016-08-14
Release date:2016-10-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:gamma-Protocadherin structural diversity and functional implications.
Elife, 5, 2016
7XH9
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BU of 7xh9 by Molmil
Crystal structure of a dimeric interlocked parallel G-quadruplex
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*CP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION, STRONTIUM ION
Authors:Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
Deposit date:2022-04-07
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
7XHD
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BU of 7xhd by Molmil
Crystal structure of a dimeric interlocked parallel G-quadruplex
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION
Authors:Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
Deposit date:2022-04-08
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
7XIE
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BU of 7xie by Molmil
Crystal structure of a dimeric interlocked parallel G-quadruplex
Descriptor: DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION
Authors:Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T.
Deposit date:2022-04-13
Release date:2023-02-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
5T9T
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BU of 5t9t by Molmil
Protocadherin Gamma B2 extracellular cadherin domains 1-5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin gamma B2-alpha C, ...
Authors:Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L.
Deposit date:2016-09-09
Release date:2016-10-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:gamma-Protocadherin structural diversity and functional implications.
Elife, 5, 2016
5V5X
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BU of 5v5x by Molmil
Protocadherin gammaB7 EC3-6 cis-dimer structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L.
Deposit date:2017-03-15
Release date:2017-11-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Protocadherin cis-dimer architecture and recognition unit diversity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7JGZ
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BU of 7jgz by Molmil
Protocadherin gammaC4 EC1-4 crystal structure
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L.
Deposit date:2020-07-20
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.
Elife, 11, 2022
4ZTD
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BU of 4ztd by Molmil
Crystal Structure of Human PCNA in complex with a TRAIP peptide
Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
Authors:Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
Deposit date:2015-05-14
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
2M59
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BU of 2m59 by Molmil
Spatial structure of dimeric VEGFR2 membrane domain in DPC micelles
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.S, Shulepko, M.A, Lyukmanova, E.N.
Deposit date:2013-02-19
Release date:2014-03-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation.
Structure, 22, 2014
2MET
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BU of 2met by Molmil
NMR spatial structure of the trimeric mutant TM domain of VEGFR2 receptor.
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.A, Shulepko, M, Lyukmanova, E.N, Kirpichnikov, M.P.
Deposit date:2013-10-02
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure, 22, 2014
2MEU
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BU of 2meu by Molmil
NMR spatial structure of mutant dimeric TM domain of VEGFR2 receptor
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Mineev, K.S, Arseniev, A.S, Lyukmanova, E.N, Shulepko, M.A, Kirpichnikov, M.P.
Deposit date:2013-10-02
Release date:2014-07-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure, 22, 2014
5M96
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BU of 5m96 by Molmil
Synthesis and biological evaluation of new triazolo and imidazolopyridine RORgt inverse agonists
Descriptor: Nuclear receptor ROR-gamma, ~{N}-[8-[[(3~{S})-4-cyclopentylcarbonyl-3-methyl-piperazin-1-yl]methyl]-7-methyl-imidazo[1,2-a]pyridin-6-yl]-2-methyl-pyrimidine-5-carboxamide
Authors:Kallen, J.
Deposit date:2016-10-31
Release date:2016-12-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Synthesis and Biological Evaluation of New Triazolo- and Imidazolopyridine ROR gamma t Inverse Agonists.
ChemMedChem, 11, 2016
6G0X
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BU of 6g0x by Molmil
TAILSPIKE PROTEIN OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ...
Authors:Gohlke, U, Broeker, N.K, Seckler, R, Barbirz, S.
Deposit date:2018-03-20
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Solvent Networks Tune Thermodynamics of Oligosaccharide Complex Formation in an Extended Protein Binding Site.
J. Am. Chem. Soc., 140, 2018
4L0E
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BU of 4l0e by Molmil
Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (heme-coordinated expression tag)
Descriptor: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Cryle, M.J.
Deposit date:2013-05-31
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis.
Acs Chem.Biol., 8, 2013
4L0F
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BU of 4l0f by Molmil
Structure of P450sky (CYP163B3), a cytochrome P450 from skyllamycin biosynthesis (open active site)
Descriptor: 1,2-ETHANEDIOL, P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Cryle, M.J.
Deposit date:2013-05-31
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cytochrome p450sky interacts directly with the nonribosomal Peptide synthetase to generate three amino Acid precursors in skyllamycin biosynthesis.
Acs Chem.Biol., 8, 2013
6GVR
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BU of 6gvr by Molmil
TAILSPIKE PROTEIN MUTANT E372Q (DELTA N471/S472) OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH PENTASACCHARIDE
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ...
Authors:Roske, Y, Gohlke, U.
Deposit date:2018-06-21
Release date:2018-07-11
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Solvent Networks Tune Thermodynamics of Oligosaccharide Complex Formation in an Extended Protein Binding Site.
J. Am. Chem. Soc., 140, 2018
6GVP
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BU of 6gvp by Molmil
TAILSPIKE PROTEIN MUTANT E372Q (DELTA N471/S472) OF E. COLI BACTERIOPHAGE HK620 IN COMPLEX WITH HEXASACCHARIDE
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ...
Authors:Roske, Y, Gohlke, U.
Deposit date:2018-06-21
Release date:2018-07-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Solvent Networks Tune Thermodynamics of Oligosaccharide Complex Formation in an Extended Protein Binding Site.
J. Am. Chem. Soc., 140, 2018
3HDN
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BU of 3hdn by Molmil
Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2
Descriptor: Serine/threonine-protein kinase Sgk1, [4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid
Authors:Zhao, B, Hammond, M.
Deposit date:2009-05-07
Release date:2009-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
3HDM
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BU of 3hdm by Molmil
Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 1
Descriptor: 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, Serine/threonine-protein kinase Sgk1
Authors:Zhao, B, Hammond, M.
Deposit date:2009-05-07
Release date:2009-06-30
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
5AO1
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BU of 5ao1 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 115-583) bound to ddGTP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ...
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO2
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BU of 5ao2 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 115-583) R164A variant bound to dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.966 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
5AO0
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BU of 5ao0 by Molmil
Crystal structure of human SAMHD1 (amino acid residues 41-583) bound to ddGTP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ...
Authors:Schwefel, D, Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.731 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015

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