1WE0
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![BU of 1we0 by Molmil](/molmil-images/mine/1we0) | Crystal structure of peroxiredoxin (AhpC) from Amphibacillus xylanus | Descriptor: | AMMONIUM ION, alkyl hydroperoxide reductase C | Authors: | Kitano, K, Kita, A, Hakoshima, T, Niimura, Y, Miki, K. | Deposit date: | 2004-05-21 | Release date: | 2005-03-29 | Last modified: | 2018-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillus xylanus Proteins, 59, 2005
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3WLV
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![BU of 3wlv by Molmil](/molmil-images/mine/3wlv) | Thermostable urate oxidase from Bacillus sp. TB-90 | Descriptor: | 8-AZAXANTHINE, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Hibi, T, Hayashi, Y, Itoh, T. | Deposit date: | 2013-11-14 | Release date: | 2014-06-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.747 Å) | Cite: | Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase. Biochemistry, 53, 2014
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7KDE
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![BU of 7kde by Molmil](/molmil-images/mine/7kde) | |
1RSM
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![BU of 1rsm by Molmil](/molmil-images/mine/1rsm) | THE 2-ANGSTROMS RESOLUTION STRUCTURE OF A THERMOSTABLE RIBONUCLEASE A CHEMICALLY CROSS-LINKED BETWEEN LYSINE RESIDUES 7 AND 41 | Descriptor: | DINITROPHENYLENE, RIBONUCLEASE A | Authors: | Weber, P.C, Sheriff, S, Ohlendorf, D.H, Finzel, B.C, Salemme, F.R. | Deposit date: | 1985-08-27 | Release date: | 1986-01-21 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2-A resolution structure of a thermostable ribonuclease A chemically cross-linked between lysine residues 7 and 41. Proc.Natl.Acad.Sci.USA, 82, 1985
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3I7V
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![BU of 3i7v by Molmil](/molmil-images/mine/3i7v) | Crystal structure of AP4A hydrolase complexed with AP4A (ATP) (aq_158) from Aquifex aeolicus Vf5 | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, AP4A hydrolase, ... | Authors: | Jeyakanthan, J, Kanaujia, S.P, Nakagawa, N, Sekar, K, Kuramitsu, S, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-07-09 | Release date: | 2009-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Free and ATP-bound structures of Ap(4)A hydrolase from Aquifex aeolicus V5 Acta Crystallogr.,Sect.D, 66, 2010
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3I7U
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![BU of 3i7u by Molmil](/molmil-images/mine/3i7u) | Crystal structure of AP4A hydrolase (aq_158) from Aquifex aeolicus VF5 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AP4A hydrolase, ... | Authors: | Jeyakanthan, J, Kanaujia, S.P, Nakagawa, N, Sekar, K, Kuramitsu, S, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2009-07-09 | Release date: | 2009-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Free and ATP-bound structures of Ap(4)A hydrolase from Aquifex aeolicus V5 Acta Crystallogr.,Sect.D, 66, 2010
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3WEX
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![BU of 3wex by Molmil](/molmil-images/mine/3wex) | Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen | Authors: | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | Deposit date: | 2013-07-16 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5 J. Mol. Biol., 426, 2014
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6AHP
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![BU of 6ahp by Molmil](/molmil-images/mine/6ahp) | Structure of the 58-167 fragment of FliL | Descriptor: | Flagellar protein FliL | Authors: | Takekawa, N, Isumi, M, Sakuma, M, Kojima, S, Homma, M, Imada, K. | Deposit date: | 2018-08-20 | Release date: | 2019-03-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure ofVibrioFliL, a New Stomatin-like Protein That Assists the Bacterial Flagellar Motor Function. MBio, 10, 2019
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6AHQ
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![BU of 6ahq by Molmil](/molmil-images/mine/6ahq) | Structure of the 40-167 fragment of FliL | Descriptor: | Flagellar protein FliL | Authors: | Takekawa, N, Isumi, M, Sakuma, M, Kojima, S, Homma, M, Imada, K. | Deposit date: | 2018-08-20 | Release date: | 2019-03-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | Structure ofVibrioFliL, a New Stomatin-like Protein That Assists the Bacterial Flagellar Motor Function. MBio, 10, 2019
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6IO0
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![BU of 6io0 by Molmil](/molmil-images/mine/6io0) | Human IDH1 R132C mutant complexed with compound A. | Descriptor: | (2E)-3-{3-[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazole-4-carbonyl]-1-methyl-1H-indol-7-yl}prop-2-enoic acid, CITRIC ACID, GLYCEROL, ... | Authors: | Suzuki, M, Baba, D, Hanzawa, H. | Deposit date: | 2018-10-29 | Release date: | 2019-10-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model. Mol.Cancer Ther., 19, 2020
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4YSH
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![BU of 4ysh by Molmil](/molmil-images/mine/4ysh) | |
7EA4
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![BU of 7ea4 by Molmil](/molmil-images/mine/7ea4) | |
7EBY
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![BU of 7eby by Molmil](/molmil-images/mine/7eby) | |
5Z5S
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![BU of 5z5s by Molmil](/molmil-images/mine/5z5s) | Crystal structure of the PPARgamma-LBD complexed with compound 13ab | Descriptor: | 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... | Authors: | Matsui, Y, Hanzawa, H. | Deposit date: | 2018-01-19 | Release date: | 2018-10-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of DS-6930, a potent selective PPAR gamma modulator. Part I: Lead identification. Bioorg. Med. Chem., 26, 2018
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5Z6S
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![BU of 5z6s by Molmil](/molmil-images/mine/5z6s) | Crystal structure of the PPARgamma-LBD complexed with compound DS-6930 | Descriptor: | 3-[[6-(3,5-dimethylpyridin-2-yl)oxy-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... | Authors: | Matsui, Y, Hanzawa, H. | Deposit date: | 2018-01-25 | Release date: | 2018-10-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of DS-6930, a potent selective PPAR gamma modulator. Part II: Lead optimization. Bioorg. Med. Chem., 26, 2018
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1MLD
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![BU of 1mld by Molmil](/molmil-images/mine/1mld) | REFINED STRUCTURE OF MITOCHONDRIAL MALATE DEHYDROGENASE FROM PORCINE HEART AND THE CONSENSUS STRUCTURE FOR DICARBOXYLIC ACID OXIDOREDUCTASES | Descriptor: | CITRIC ACID, MALATE DEHYDROGENASE | Authors: | Gleason, W.B, Fu, Z, Birktoft, J.J, Banaszak, L.J. | Deposit date: | 1994-01-24 | Release date: | 1995-01-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Refined crystal structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases. Biochemistry, 33, 1994
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4J6R
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![BU of 4j6r by Molmil](/molmil-images/mine/4j6r) | Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, ... | Authors: | Zhou, T, Moquin, S, Kwong, P.D. | Deposit date: | 2013-02-11 | Release date: | 2013-05-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science, 340, 2013
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4JB9
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![BU of 4jb9 by Molmil](/molmil-images/mine/4jb9) | Crystal structure of antibody VRC06 in complex with HIV-1 gp120 core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, antibody VRC06 heavy chain, antibody VRC06 light chain, ... | Authors: | Kwon, Y.D, Zhou, T, Srivatsan, S, Kwong, P.D. | Deposit date: | 2013-02-19 | Release date: | 2013-05-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science, 340, 2013
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2CVQ
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![BU of 2cvq by Molmil](/molmil-images/mine/2cvq) | Crystal structure of NAD(H)-dependent malate dehydrogenase complexed with NADPH | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | Deposit date: | 2005-06-13 | Release date: | 2005-08-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H) Biochem.Biophys.Res.Commun., 334, 2005
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3A6J
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![BU of 3a6j by Molmil](/molmil-images/mine/3a6j) | E122Q mutant creatininase complexed with creatine | Descriptor: | Creatinine amidohydrolase, N-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE, SULFATE ION, ... | Authors: | Nakajima, Y, Yamashita, K, Ito, K, Yoshimoto, T. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase J.Mol.Biol., 396, 2010
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3A6D
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![BU of 3a6d by Molmil](/molmil-images/mine/3a6d) | Creatininase complexed with 1-methylguanidine | Descriptor: | 1-METHYLGUANIDINE, Creatinine amidohydrolase, MANGANESE (II) ION, ... | Authors: | Nakajima, Y, Yamashita, K, Ito, K, Yoshimoto, T. | Deposit date: | 2009-08-31 | Release date: | 2010-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase J.Mol.Biol., 396, 2010
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2ZQE
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![BU of 2zqe by Molmil](/molmil-images/mine/2zqe) | Crystal structure of the Smr domain of Thermus thermophilus MutS2 | Descriptor: | MutS2 protein | Authors: | Fukui, K, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S. | Deposit date: | 2008-08-08 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression J.Biol.Chem., 283, 2008
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3A6H
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![BU of 3a6h by Molmil](/molmil-images/mine/3a6h) | W154A mutant creatininase | Descriptor: | CHLORIDE ION, Creatinine amidohydrolase, MANGANESE (II) ION, ... | Authors: | Nakajima, Y, Yamashita, K, Ito, K, Yoshimoto, T. | Deposit date: | 2009-08-31 | Release date: | 2010-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase J.Mol.Biol., 396, 2010
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3A6L
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![BU of 3a6l by Molmil](/molmil-images/mine/3a6l) | E122Q mutant creatininase, Zn-Zn type | Descriptor: | CHLORIDE ION, Creatinine amidohydrolase, ZINC ION | Authors: | Nakajima, Y, Yamashita, K, Ito, K, Yoshimoto, T. | Deposit date: | 2009-09-02 | Release date: | 2010-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase J.Mol.Biol., 396, 2010
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5AYT
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![BU of 5ayt by Molmil](/molmil-images/mine/5ayt) | Crystal structure of transthyretin in complex with L6 | Descriptor: | 2-oxidanyl-6-(phenylcarbonyl)benzo[de]isoquinoline-1,3-dione, Transthyretin | Authors: | Yokoyama, T, Mizuguchi, M, Kai, H. | Deposit date: | 2015-09-03 | Release date: | 2016-01-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione J. Pharmacol. Sci., 129, 2015
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