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8PEN
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BU of 8pen by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PIM
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BU of 8pim by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (not complementary scaffold)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-22
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PDY
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BU of 8pdy by Molmil
E. coli RNA polymerase paused at ops site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-13
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PH9
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BU of 8ph9 by Molmil
E. coli RNA polymerase paused at ops site (non-complementary scaffold)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PFG
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BU of 8pfg by Molmil
autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex), not fully complementary scaffold
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-15
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PIB
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BU of 8pib by Molmil
autoinhibited RfaH bound to E. coli transcription complex paused at ops site (encounter complex)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-21
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PHK
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BU of 8phk by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-20
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
7U34
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BU of 7u34 by Molmil
The structure of phosphoglucose isomerase from Aspergillus fumigatus
Descriptor: CHLORIDE ION, CITRATE ANION, GLYCEROL, ...
Authors:Yan, K, Kowalski, B, Fang, W, van Aalten, D.
Deposit date:2022-02-25
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis.
Mbio, 13, 2022
3GLK
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BU of 3glk by Molmil
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2)
Descriptor: Acetyl-CoA carboxylase 2
Authors:Price, A, Kulathila, R.
Deposit date:2009-03-12
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase.
Bioorg.Med.Chem.Lett., 19, 2009
3G86
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BU of 3g86 by Molmil
Hepatitis C virus polymerase NS5B (BK 1-570) with thiazine inhibitor
Descriptor: N-{3-[6-fluoro-1-(4-fluorobenzyl)-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Harris, S.F, Ghate, M.
Deposit date:2009-02-11
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones
Bioorg.Med.Chem.Lett., 19, 2009
5F9P
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BU of 5f9p by Molmil
Crystal structure study of anthrone oxidase-like protein
Descriptor: Anthrone oxidase-like protein, GLYCEROL
Authors:Gao, X, Wu, D, Fan, K, Liu, Z.-J.
Deposit date:2015-12-10
Release date:2016-12-14
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.078 Å)
Cite:Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis
ACS Chem. Biol., 12, 2017
3GID
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BU of 3gid by Molmil
The biotin carboxylase (BC) domain of human Acetyl-CoA Carboxylase 2 (ACC2) in complex with Soraphen A
Descriptor: Acetyl-CoA carboxylase 2, SORAPHEN A
Authors:Price, A, Kulathila, R.
Deposit date:2009-03-05
Release date:2009-03-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis and characterization of a BODIPY-labeled derivative of Soraphen A that binds to acetyl-CoA carboxylase.
Bioorg.Med.Chem.Lett., 19, 2009
3H59
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BU of 3h59 by Molmil
Hepatitis C virus polymerase NS5B with thiazine inhibitor 2
Descriptor: N-{3-[(5S)-5-(1,1-dimethylpropyl)-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase
Authors:Harris, S.F, Ghate, M.
Deposit date:2009-04-21
Release date:2009-09-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids
Bioorg.Med.Chem.Lett., 19, 2009
7M4T
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BU of 7m4t by Molmil
Menin bound to M-1121
Descriptor: Menin, methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate, praseodymium triacetate
Authors:Stuckey, J.
Deposit date:2021-03-22
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.
J.Med.Chem., 64, 2021
7VLN
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BU of 7vln by Molmil
NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound
Descriptor: 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2
Authors:Cao, D.Y, Li, Y.L, Li, J, Xiong, B.
Deposit date:2021-10-05
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
J.Med.Chem., 65, 2022
6II9
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BU of 6ii9 by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L3A-44
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L3A-44 Fab, Hemagglutinin, ...
Authors:Jiang, H.H, Shi, Y, Qi, J, Gao, G.F.
Deposit date:2018-10-03
Release date:2018-10-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
6II8
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BU of 6ii8 by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4B-18
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L4B-18 Fab, Hemagglutinin, ...
Authors:Jiang, H.H, Shi, Y, Qi, J, Gao, G.F.
Deposit date:2018-10-03
Release date:2018-10-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
8WY7
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BU of 8wy7 by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 22
Descriptor: 2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]-~{N}-(4-oxidanylcyclohexyl)ethanamide, Bromodomain-containing protein 4
Authors:Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X.
Deposit date:2023-10-30
Release date:2024-01-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia.
J.Med.Chem., 67, 2024
8XK5
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BU of 8xk5 by Molmil
SNB1G11 Fab bound to SFTSV glycoprotein Gn
Descriptor: Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain
Authors:Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
8XK8
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BU of 8xk8 by Molmil
N1D10 Fab bound to SFTSV glycoprotein-Gn
Descriptor: Envelopment polyprotein, mAb N1D10 Fab heavy chain, mAb N1D10 Fab light chain
Authors:Zhao, H, Deng, Z.
Deposit date:2023-12-22
Release date:2024-07-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.53 Å)
Cite:A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
To Be Published
8JGT
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BU of 8jgt by Molmil
Crystal structure of Deinococcus radiodurans exopolyphosphatase E114A mutant
Descriptor: Exopolyphosphatase, MAGNESIUM ION, SULFATE ION
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGR
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BU of 8jgr by Molmil
Crystal structure of Deinococcus radiodurans exopolyphosphatase in the presence of Pi
Descriptor: Exopolyphosphatase, PHOSPHATE ION, POTASSIUM ION
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGX
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BU of 8jgx by Molmil
Crystal structure of Acinetobacter baumannii exopolyphosphatase
Descriptor: Exopolyphosphatase
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGW
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BU of 8jgw by Molmil
Crystal structure of Klebsiella pneumoniae exopolyphosphatase
Descriptor: Exopolyphosphatase, GLYCEROL, MAGNESIUM ION, ...
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024
8JGU
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BU of 8jgu by Molmil
Crystal structure of N-terminal domain of exopolyphosphatase from Deinococcus radiodurans
Descriptor: Exopolyphosphatase, SODIUM ION
Authors:Zhao, Y, Dai, S.
Deposit date:2023-05-21
Release date:2024-05-15
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural Evolution of Bacterial Polyphosphate Degradation Enzyme for Phosphorus Cycling.
Adv Sci, 11, 2024

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