3WQ8
| Monomer structure of hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form | Descriptor: | Beta-glucosidase | Authors: | Nakabayashi, M, Kataoka, M, Watanabe, M, Ishikawa, K. | Deposit date: | 2014-01-23 | Release date: | 2014-07-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Monomer structure of a hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form. Acta Crystallogr.,Sect.F, 70, 2014
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4H8N
| Crystal structure of conjugated polyketone reductase C2 from candida parapsilosis complexed with NADPH | Descriptor: | Conjugated polyketone reductase C2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Qin, H.-M, Yamamura, A, Miyakawa, T, Maruoka, S, Ohtsuka, J, Nagata, K, Kataoka, M, Shimizu, S, Tanokura, M. | Deposit date: | 2012-09-23 | Release date: | 2013-08-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding Appl.Microbiol.Biotechnol., 98, 2014
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3B3K
| Crystal structure of the complex between PPARgamma and the full agonist LT175 | Descriptor: | (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Mazza, F, Loiodice, F, Fracchiolla, G, Crestani, M, Godio, C. | Deposit date: | 2007-10-22 | Release date: | 2008-10-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the Peroxisome Proliferator-Activated Receptor gamma (PPARgamma) Ligand Binding Domain Complexed with a Novel Partial Agonist: A New Region of the Hydrophobic Pocket Could Be Exploited for Drug Design J.Med.Chem., 51, 2008
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2KWC
| The NMR structure of the autophagy-related protein Atg8 | Descriptor: | Autophagy-related protein 8 | Authors: | Kumeta, H, Watanabe, M, Nakatogawa, H, Yamaguchi, M, Ogura, K, Adachi, W, Fujioka, Y, Noda, N.N, Ohsumi, Y, Inagaki, F. | Deposit date: | 2010-04-05 | Release date: | 2010-05-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The NMR structure of the autophagy-related protein Atg8 J.Biomol.Nmr, 47, 2010
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2KSW
| Backbone 1H, 13C, and 15N Chemical Shift Assignments for Oryctin | Descriptor: | Oryctin | Authors: | Horita, S, Ishibashi, J, Nagata, K, Miyakawa, T, Yamakawa, M, Tanokura, M. | Deposit date: | 2010-01-14 | Release date: | 2010-07-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Isolation, cDNA cloning, and structure-based functional characterization of oryctin, a hemolymph protein from the coconut rhinoceros beetle, Oryctes rhinoceros, as a novel serine protease inhibitor J.Biol.Chem., 285, 2010
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4IJ6
| Crystal Structure of a Novel-type Phosphoserine Phosphatase Mutant (H9A) from Hydrogenobacter thermophilus TK-6 in Complex with L-phosphoserine | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHOSERINE, ... | Authors: | Chiba, Y, Horita, S, Ohtsuka, J, Arai, H, Nagata, K, Igarashi, Y, Tanokura, M, Ishii, M. | Deposit date: | 2012-12-21 | Release date: | 2013-03-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural units important for activity of a novel-type phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6 revealed by crystal structure analysis J.Biol.Chem., 288, 2013
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2GXG
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4IJ5
| Crystal Structure of a Novel-type Phosphoserine Phosphatase from Hydrogenobacter thermophilus TK-6 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Phosphoserine phosphatase 1 | Authors: | Chiba, Y, Horita, S, Ohtsuka, J, Arai, H, Nagata, K, Igarashi, Y, Tanokura, M, Ishii, M. | Deposit date: | 2012-12-21 | Release date: | 2013-03-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural units important for activity of a novel-type phosphoserine phosphatase from Hydrogenobacter thermophilus TK-6 revealed by crystal structure analysis J.Biol.Chem., 288, 2013
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2D37
| The Crystal Structure of Flavin Reductase HpaC complexed with NAD+ | Descriptor: | FLAVIN MONONUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, hypothetical NADH-dependent FMN oxidoreductase | Authors: | Okai, M, Kudo, N, Lee, W.C, Kamo, M, Nagata, K, Tanokura, M. | Deposit date: | 2005-09-26 | Release date: | 2006-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of the short-chain flavin reductase HpaC from Sulfolobus tokodaii strain 7 in its three states: NAD(P)(+)(-)free, NAD(+)(-)bound, and NADP(+)(-)bound Biochemistry, 45, 2006
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2D36
| The Crystal Structure of Flavin Reductase HpaC | Descriptor: | FLAVIN MONONUCLEOTIDE, hypothetical NADH-dependent FMN oxidoreductase | Authors: | Okai, M, Kudo, N, Lee, W.C, Kamo, M, Nagata, K, Tanokura, M. | Deposit date: | 2005-09-26 | Release date: | 2006-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of the short-chain flavin reductase HpaC from Sulfolobus tokodaii strain 7 in its three states: NAD(P)(+)(-)free, NAD(+)(-)bound, and NADP(+)(-)bound Biochemistry, 45, 2006
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2LDS
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2K2J
| NMR solution structure of the split PH domain from Phospholipase C gamma 2 | Descriptor: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 | Authors: | Harris, R, Bunney, T.D, Katan, M, Driscoll, P.C. | Deposit date: | 2008-04-02 | Release date: | 2008-09-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Rac Regulates Its Effector Phospholipase C{gamma}2 through Interaction with a Split Pleckstrin Homology Domain. J.Biol.Chem., 283, 2008
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3LNQ
| Structure of Aristaless homeodomain in complex with DNA | Descriptor: | 5'-D(*CP*CP*CP*TP*AP*AP*TP*TP*AP*AP*AP*CP*CP*C)-3', 5'-D(*GP*GP*GP*TP*TP*TP*AP*AP*TP*TP*AP*GP*GP*G)-3', ACETATE ION, ... | Authors: | Takamura, Y, Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. | Deposit date: | 2010-02-02 | Release date: | 2010-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
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4D7Y
| Crystal structure of mouse C1QL1 globular domain | Descriptor: | C1Q-RELATED FACTOR, CADMIUM ION, CHLORIDE ION, ... | Authors: | Kakegawa, W, Mitakidis, N, Miura, E, Abe, M, Matsuda, K, Takeo, Y, Kohda, K, Motohashi, J, Takahashi, A, Nagao, S, Muramatsu, S, Watanabe, M, Sakimura, K, Aricescu, A.R, Yuzaki, M. | Deposit date: | 2014-12-01 | Release date: | 2015-01-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Anterograde C1Ql1 Signaling is Required in Order to Determine and Maintain a Single-Winner Climbing Fiber in the Mouse Cerebellum Neuron, 85, 2015
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7WSV
| Cryo-EM structure of the N-terminal deletion mutant of human pannexin-1 in a nanodisc | Descriptor: | Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2022-02-01 | Release date: | 2022-02-16 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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1UAW
| Solution structure of the N-terminal RNA-binding domain of mouse Musashi1 | Descriptor: | mouse-musashi-1 | Authors: | Miyanoiri, Y, Kobayashi, H, Watanabe, M, Ikeda, T, Nagata, T, Okano, H, Uesugi, S, Katahira, M. | Deposit date: | 2003-03-24 | Release date: | 2004-03-24 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics J.Biol.Chem., 278, 2003
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7F8J
| Cryo-EM structure of human pannexin-1 in a nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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7F8O
| Cryo-EM structure of the C-terminal deletion mutant of human PANX1 in a nanodisc | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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7F8N
| Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Pannexin-1 | Authors: | Kuzuya, M, Hirano, H, Hayashida, K, Watanabe, M, Kobayashi, K, Tani, K, Fujiyoshi, Y, Oshima, A. | Deposit date: | 2021-07-02 | Release date: | 2022-01-26 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids. Sci.Signal., 15, 2022
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6JNR
| RXRa structure complexed with CU-6PMN and SRC1 peptide. | Descriptor: | 7-oxidanyl-2-oxidanylidene-6-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)chromene-3-carboxylic acid, HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Retinoic acid receptor RXR-alpha | Authors: | Kawasaki, M, Nakano, S, Motoyama, T, Yamada, S, Watanabe, M, Takamura, Y, Fujihara, M, Tokiwa, H, Kakuta, H, Ito, S. | Deposit date: | 2019-03-18 | Release date: | 2020-03-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | RXRa structure complexed with CU-6PMN and SRC1 peptide. To Be Published
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5GMT
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5H3E
| Crystal structure of mouse isocitrate dehydrogenases 2 K256Q mutant complexed with isocitrate | Descriptor: | ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], mitochondrial, ... | Authors: | Xu, Y, Liu, L, Miyakawa, T, Nakamura, A, Tanokura, M. | Deposit date: | 2016-10-23 | Release date: | 2017-08-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics Sci Rep, 7, 2017
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5H3F
| Crystal structure of mouse isocitrate dehydrogenases 2 complexed with isocitrate | Descriptor: | ISOCITRIC ACID, Isocitrate dehydrogenase [NADP], mitochondrial, ... | Authors: | Xu, Y, Liu, L, Miyakawa, T, Nakamura, A, Tanokura, M. | Deposit date: | 2016-10-23 | Release date: | 2017-08-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics Sci Rep, 7, 2017
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5DNV
| Crystal structure of KAI2-like protein from Striga (apo state 2) | Descriptor: | BENZOIC ACID, FORMIC ACID, ShKAI2iB | Authors: | Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. | Deposit date: | 2015-09-10 | Release date: | 2016-08-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis of unique ligand specificity of KAI2-like protein from parasitic weed Striga hermonthica Sci Rep, 6, 2016
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3OV3
| G211F mutant of curcumin synthase 1 from Curcuma longa | Descriptor: | Curcumin synthase, MALONATE ION | Authors: | Katsuyama, Y, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | Deposit date: | 2010-09-15 | Release date: | 2010-12-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A hydrophobic cavity discovered in a curcumin synthase facilitates utilization of a beta-keto acid as an extender substrate for the atypical type III polyleteide synthase To be Published
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