8XQA
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2GQG
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![BU of 2gqg by Molmil](/molmil-images/mine/2gqg) | X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain | Descriptor: | GLYCEROL, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase ABL1 | Authors: | Klei, H.E. | Deposit date: | 2006-04-20 | Release date: | 2006-11-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants CANCER RES., 66, 2006
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7X6Y
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8XQ7
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8XPQ
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8XQ9
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2I5F
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![BU of 2i5f by Molmil](/molmil-images/mine/2i5f) | Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,5,6)P5 | Descriptor: | (1R,2R,3R,4R,5S,6S)-6-HYDROXYCYCLOHEXANE-1,2,3,4,5-PENTAYL PENTAKIS[DIHYDROGEN (PHOSPHATE)], Pleckstrin | Authors: | Jackson, S.G, Haslam, R.J, Junop, M.S. | Deposit date: | 2006-08-24 | Release date: | 2007-08-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate. Bmc Struct.Biol., 7, 2007
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6JUZ
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![BU of 6juz by Molmil](/molmil-images/mine/6juz) | Crystal Structure of N-terminal domain of ArgZ(N71S) covalently bond to a reaction intermediate | Descriptor: | 1,2-ETHANEDIOL, ARGININE, Sll1336 protein | Authors: | Zhuang, N, Li, L, Wu, X, Zhuang, Y. | Deposit date: | 2019-04-15 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism. J.Biol.Chem., 295, 2020
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3C6D
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![BU of 3c6d by Molmil](/molmil-images/mine/3c6d) | The pseudo-atomic structure of dengue immature virus | Descriptor: | Polyprotein, prM | Authors: | Li, L. | Deposit date: | 2008-02-04 | Release date: | 2008-04-08 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12.5 Å) | Cite: | The flavivirus precursor membrane-envelope protein complex: structure and maturation Science, 319, 2008
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2I47
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![BU of 2i47 by Molmil](/molmil-images/mine/2i47) | Crystal structure of catalytic domain of TACE with inhibitor | Descriptor: | 4-({[4-(BUT-2-YN-1-YLOXY)PHENYL]SULFONYL}METHYL)-1-[(3,5-DIMETHYLISOXAZOL-4-YL)SULFONYL]-N-HYDROXYPIPERIDINE-4-CARBOXAMIDE, ADAM 17, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... | Authors: | Xu, W, Condon, J.S, Lovering, F.E. | Deposit date: | 2006-08-21 | Release date: | 2006-12-05 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of potent and selective TACE inhibitors via the S1 pocket. Bioorg.Med.Chem.Lett., 17, 2007
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3C5X
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![BU of 3c5x by Molmil](/molmil-images/mine/3c5x) | Crystal structure of the precursor membrane protein- envelope protein heterodimer from the dengue 2 virus at low pH | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-altropyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, L. | Deposit date: | 2008-02-01 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science, 319, 2008
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7Y0W
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![BU of 7y0w by Molmil](/molmil-images/mine/7y0w) | Local structure of BD55-5514 and BD55-5840 Fab and Omicron BA.1 RBD complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-5514H, BD55-5514L, ... | Authors: | Zhang, Z, Xiao, J. | Deposit date: | 2022-06-06 | Release date: | 2022-09-28 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents. Cell Rep, 41, 2022
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6KTH
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![BU of 6kth by Molmil](/molmil-images/mine/6kth) | Crystal structure of Juvenile hormone diol kinase JHDK-L2 from silkworm, Bombyx mori | Descriptor: | CALCIUM ION, GLYCEROL, Juvenile hormone diol kinase | Authors: | Zhang, Y.S, Xu, H.Y, Wang, Z, Zhang, L, Zhao, P, Guo, P.C. | Deposit date: | 2019-08-28 | Release date: | 2020-09-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori. Int.J.Biol.Macromol., 167, 2021
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2H0D
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3CZO
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2I5C
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![BU of 2i5c by Molmil](/molmil-images/mine/2i5c) | Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,4,5)P5 | Descriptor: | (1R,2S,3R,4S,5S,6R)-6-HYDROXYCYCLOHEXANE-1,2,3,4,5-PENTAYL PENTAKIS[DIHYDROGEN (PHOSPHATE)], Pleckstrin | Authors: | Jackson, S.G, Haslam, R.J, Junop, M.S. | Deposit date: | 2006-08-24 | Release date: | 2007-08-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate. Bmc Struct.Biol., 7, 2007
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2F5I
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3F9F
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3NXS
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3OL3
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7WI0
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![BU of 7wi0 by Molmil](/molmil-images/mine/7wi0) | SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
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7WHZ
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![BU of 7whz by Molmil](/molmil-images/mine/7whz) | SARS-CoV-2 spike protein in complex with three human neutralizing antibodies | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | Authors: | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | Deposit date: | 2022-01-01 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron. Cell Rep, 39, 2022
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3OL4
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3GVG
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3GWC
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