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4LCW
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BU of 4lcw by Molmil
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
Descriptor: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2013-06-24
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
J.Exp.Med., 210, 2013
5U17
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BU of 5u17 by Molmil
Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR
Descriptor: 2,4-diaminopteridine-6-carbaldehyde, ACETATE ION, Beta-2-microglobulin, ...
Authors:Keller, A.N, Rossjohn, J.
Deposit date:2016-11-28
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
5U2V
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BU of 5u2v by Molmil
Structure of human MR1-HMB in complex with human MAIT A-F7 TCR
Descriptor: 2-hydroxy-5-methoxybenzaldehyde, Beta-2-microglobulin, GLYCEROL, ...
Authors:Keller, A.N, Rossjohn, J.
Deposit date:2016-12-01
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
3KYN
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BU of 3kyn by Molmil
Crystal structure of HLA-G presenting KGPPAALTL peptide
Descriptor: Beta-2-microglobulin, CHLORIDE ION, COBALT (II) ION, ...
Authors:Walpole, N.G, Rossjohn, J, Clements, C.S.
Deposit date:2009-12-06
Release date:2010-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide
J.Mol.Biol., 397, 2010
3SDX
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BU of 3sdx by Molmil
Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide
Descriptor: Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide, ...
Authors:Clarke, A.J, Patel, O, Rossjohn, J.
Deposit date:2011-06-09
Release date:2011-10-05
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
3L3J
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BU of 3l3j by Molmil
Crystal structure of HLA-B*4402 in complex with the F3A/R5A double mutant of a self-peptide derived from DPA*0201
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Ely, L.K, Rossjohn, J.
Deposit date:2009-12-17
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
5U1R
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BU of 5u1r by Molmil
Structure of human MR1-diclofenac in complex with human MAIT A-F7 TCR
Descriptor: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ACETATE ION, Beta-2-microglobulin, ...
Authors:Keller, A.N, Rossjohn, J.
Deposit date:2016-11-28
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
3L3D
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BU of 3l3d by Molmil
Crystal structure of HLA-B*4402 in complex with the F3A mutant of a self-peptide derived from DPA*0201
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Theodossis, A, Ely, L.K, Rossjohn, J.
Deposit date:2009-12-16
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
3L3K
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BU of 3l3k by Molmil
Crystal structure of HLA-B*4402 in complex with the R5A/F7A double mutant of a self-peptide derived from DPA*0201
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Ely, L.K, Rossjohn, J.
Deposit date:2009-12-17
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
3HUJ
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BU of 3huj by Molmil
Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, MAGNESIUM ION, ...
Authors:Pang, S.S.
Deposit date:2009-06-14
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Immunity, 31, 2009
5VWD
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BU of 5vwd by Molmil
HLA-B*57:03 presenting LTVQVARVW
Descriptor: Beta-2-microglobulin, MHC class I antigen, Noamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TRP
Authors:Pymm, P, Rossjohn, J, Vivian, J.P.
Deposit date:2017-05-21
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
6BWW
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BU of 6bww by Molmil
Crystal structure of an acetate and Cymal-5 bound cytochrome P450 2B4 F429H mutant
Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ACETATE ION, Cytochrome P450 2B4, ...
Authors:Yang, Y.T, Waskell, L.
Deposit date:2017-12-15
Release date:2018-12-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam.
J.Inorg.Biochem., 185, 2018
3LN4
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BU of 3ln4 by Molmil
Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2
Descriptor: 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ...
Authors:Theodossis, A, Gras, S, Rossjohn, J.
Deposit date:2010-02-01
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.296 Å)
Cite:The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
3DX6
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BU of 3dx6 by Molmil
Crystal Structure of B*4402 presenting a 10mer EBV epitope
Descriptor: ACETATE ION, Beta-2-microglobulin, EBV decapeptide epitope, ...
Authors:Archbold, J.K, Ely, L.K, Rossjohn, J.
Deposit date:2008-07-23
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
5VVP
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BU of 5vvp by Molmil
HLA-B*57:03 presenting LSSPVTKSW
Descriptor: Beta-2-microglobulin, LEU-SER-SER-PRO-VAL-THR-LYS-SER-TRP, MHC class I antigen
Authors:Pymm, P, Rossjohn, J, Vivian, J.P.
Deposit date:2017-05-19
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3L3I
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BU of 3l3i by Molmil
Crystal structure of HLA-B*4402 in complex with the F7A mutant of a self-peptide derived from DPA*0201
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Ely, L.K, Rossjohn, J.
Deposit date:2009-12-17
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
3L3G
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BU of 3l3g by Molmil
Crystal structure of HLA-B*4402 in complex with the R5A mutant of a self-peptide derived from DPA*0201
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Theodossis, A, Ely, L.K, Rossjohn, J.
Deposit date:2009-12-16
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
3KYO
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BU of 3kyo by Molmil
Crystal structure of HLA-G presenting KLPAQFYIL peptide
Descriptor: Beta-2-microglobulin, COBALT (II) ION, KLPAQFYIL peptide, ...
Authors:Walpole, N.G, Rossjohn, J, Clements, C.S.
Deposit date:2009-12-06
Release date:2010-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure and stability of the monomorphic HLA-G are influenced by the nature of the bound peptide
J.Mol.Biol., 397, 2010
5VWF
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BU of 5vwf by Molmil
HLA-B*58:03 presenting LTVQVARVY
Descriptor: Beta-2-microglobulin, MHC class I antigen, Nonamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TYR
Authors:Pymm, P, Rossjohn, J, Vivian, J.P.
Deposit date:2017-05-21
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
5VUD
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BU of 5vud by Molmil
HLA-B*57:01 presenting LSSPVTKSW
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
Authors:Pymm, P, Rossjohn, J, Vivian, J.P.
Deposit date:2017-05-19
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3L3H
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BU of 3l3h by Molmil
X-ray crystal structure of the F6A mutant of influenza A acid polymerase epitope PA224 bound to murine H2-Db MHC
Descriptor: 10-mer peptide from Polymerase acidic protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Welland, A, Clements, C.S, Dunstone, M.A, Rossjohn, J.
Deposit date:2009-12-17
Release date:2010-03-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
3LN5
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BU of 3ln5 by Molmil
Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase
Descriptor: 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Gras, S, Rossjohn, J.
Deposit date:2010-02-02
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
3HE6
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BU of 3he6 by Molmil
Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta8.2 NKT TCR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2009-05-07
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Immunity, 31, 2009
4PJH
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BU of 4pjh by Molmil
Structure of human MR1-Ac-6-FP in complex with human MAIT B-G8 TCR
Descriptor: Beta-2-microglobulin, GLYCEROL, Major histocompatibility complex class I-related gene protein, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-05-12
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
4PJ9
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BU of 4pj9 by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT TRAJ20 TCR
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-05-12
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014

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