3L3I

Crystal structure of HLA-B*4402 in complex with the F7A mutant of a self-peptide derived from DPA*0201

Summary for 3L3I

• Entry DOI: 10.2210/pdb3l3i/pdb
• Related: 1M6O 3L3D 3L3G 3L3J 3L3K
• Descriptor: HLA class I histocompatibility antigen, B-44 alpha chain, Beta-2-microglobulin, peptide from HLA-DPA1 protein, ... (5 entities in total)
• Functional Keywords: immunoglobulin domain, immune response, major histocompatibility complex class i, mhc-i peptide complex, altered peptide ligand, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P30481; Secreted: P61769
• Total number of polymer chains: 3
• Total formula weight: 45110.86

Authors

Theodossis, A.,Ely, L.K.,Rossjohn, J. (deposition date: 2009-12-17, release date: 2010-03-16, Last modification date: 2023-11-01)

• Primary citation: Theodossis, A.,Guillonneau, C.,Welland, A.,Ely, L.K.,Clements, C.S.,Williamson, N.A.,Webb, A.I.,Wilce, J.A.,Mulder, R.J.,Dunstone, M.A.,Doherty, P.C.,McCluskey, J.,Purcell, A.W.,Turner, S.J.,Rossjohn, J.; Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition; Proc.Natl.Acad.Sci.USA, 107:5534-5539, 2010; PubMed: 20212169; DOI: 10.1073/pnas.1000032107

Experimental method

X-RAY DIFFRACTION (1.7 Å)