2KIE
| A PH domain within OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolis | 分子名称: | Inositol polyphosphate 5-phosphatase OCRL-1 | 著者 | Mao, Y, Balkin, D.M, Zoncu, R, Erdmann, K, Tomasini, L, Hu, F, Jin, M.M, Hodsdon, M.E, De Camilli, P. | 登録日 | 2009-05-03 | 公開日 | 2009-07-21 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism Embo J., 28, 2009
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8DHB
| Active FLCN GAP complex | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Folliculin, Folliculin-interacting protein 2, ... | 著者 | Jansen, R.M, Hurley, J.H. | 登録日 | 2022-06-25 | 公開日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation. Sci Adv, 8, 2022
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6B9X
| Crystal structure of Ragulator | 分子名称: | Hepatitis B virus x interacting protein, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ... | 著者 | SU, M.-Y, Hurley, J.H. | 登録日 | 2017-10-11 | 公開日 | 2017-11-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex. Mol. Cell, 68, 2017
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6NZD
| Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator) | 分子名称: | 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione, Folliculin, Folliculin-interacting protein 2, ... | 著者 | Fromm, S.A, Young, L.N, Hurley, J.H. | 登録日 | 2019-02-13 | 公開日 | 2019-11-06 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science, 366, 2019
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6V4U
| Cryo-EM structure of SMCR8-C9orf72-WDR41 complex | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | 著者 | Su, M.Y, Hurley, J.H. | 登録日 | 2019-12-01 | 公開日 | 2020-09-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Nature, 585, 2020
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2QV2
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2KIG
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