1N7T
 
 | | ERBIN PDZ domain bound to a phage-derived peptide | | 分子名称: | 99-mer peptide of densin-180-like protein, phage-derived peptide | | 著者 | Skelton, N.J, Koehler, M.F.T, Zobel, K, Wong, W.L, Yeh, S, Pisabarro, M.T, Yin, J.P, Lasky, L.A, Sidhu, S.S. | | 登録日 | 2002-11-16 | | 公開日 | 2003-01-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the Erbin PDZ domain.
J.Biol.Chem., 278, 2003
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8VUG
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3P08
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3HR5
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2H2B
 | | Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTYL) | | 分子名称: | ACETIC ACID, Tight junction protein ZO-1 | | 著者 | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | | 登録日 | 2006-05-18 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
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2H3M
 | | Crystal Structure of ZO-1 PDZ1 | | 分子名称: | SULFATE ION, Tight junction protein ZO-1 | | 著者 | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | | 登録日 | 2006-05-22 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
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2H3L
 | | Crystal Structure of ERBIN PDZ | | 分子名称: | LAP2 protein | | 著者 | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | | 登録日 | 2006-05-22 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
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2H2C
 | | Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTWV) | | 分子名称: | Tight junction protein ZO-1 | | 著者 | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | | 登録日 | 2006-05-18 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
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7USY
 | | Structure of C. elegans TMC-1 complex with ARRD-6 | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jeong, H, Clark, S, Gouaux, E. | | 登録日 | 2022-04-26 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
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7USW
 | | Structure of Expanded C. elegans TMC-1 complex | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jeong, H, Clark, S, Gouaux, E. | | 登録日 | 2022-04-26 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
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7USX
 | | Structure of Contracted C. elegans TMC-1 complex | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jeong, H, Clark, S, Gouaux, E. | | 登録日 | 2022-04-26 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structures of the TMC-1 complex illuminate mechanosensory transduction.
Nature, 610, 2022
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8EDW
 | | Cryo-EM Structure of human ABCA7 in BPL/Ch Nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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8EEB
 | | Cryo-EM structure of human ABCA7 in Digitonin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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8BHT
 | | ABCG2 turnover-1 state with tariquidar bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ... | | 著者 | Yu, Q, Kowal, J, Tajkhorshid, E, Locher, K.P. | | 登録日 | 2022-10-31 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8BI0
 | | ABCG2 turnover-2 state with tariquidar bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL, ... | | 著者 | Yu, Q, Kowal, J, Tajkhorshid, E, Locher, K.P. | | 登録日 | 2022-11-01 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EE6
 | | Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phospholipid-transporting ATPase ABCA7, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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8EOP
 | | Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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7LGU
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7LGW
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7LH3
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7LH2
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5J44
 | | Crystal structure of the Secreted Extracellular protein A (SepA) from Shigella flexneri | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Serine protease SepA autotransporter | | 著者 | Birtley, J.R, Stern, L.J, McCormick, B, Maldonado-Contreras, A. | | 登録日 | 2016-03-31 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.912 Å) | | 主引用文献 | Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.
Gut Microbes, 8, 2017
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