6PBF
| ZINC9155420-bound TRPV5 in nanodiscs | 分子名称: | (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate, Transient receptor potential cation channel subfamily V member 5 | 著者 | Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2019-06-13 | 公開日 | 2019-11-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure-based characterization of novel TRPV5 inhibitors. Elife, 8, 2019
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6PBE
| ZINC17988990-bound TRPV5 in nanodiscs | 分子名称: | (4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)methyl 3-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)propanoate, Transient receptor potential cation channel subfamily V member 5 | 著者 | Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2019-06-13 | 公開日 | 2019-11-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structure-based characterization of novel TRPV5 inhibitors. Elife, 8, 2019
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7T6J
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7T6K
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7T6M
| Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1 | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
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7T6R
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7T6Q
| Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
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7T6P
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7T6L
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7T6O
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7T6N
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6DMR
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6DMW
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6DMU
| PI(4,5)P2 bound full-length rbTRPV5 | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. | 登録日 | 2018-06-05 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural insights on TRPV5 gating by endogenous modulators. Nat Commun, 9, 2018
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