6IE8
 
 | | RamR in complex with cholic acid | | 分子名称: | CHOLIC ACID, Regulatory protein, SULFATE ION | | 著者 | Nakashima, R, Sakurai, K, Yamasaki, S, Nishino, K. | | 登録日 | 2018-09-13 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the multidrug resistance regulator RamR complexed with bile acids.
Sci Rep, 9, 2019
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6IE9
 | | RamR in complex with chenodeoxycholic acid | | 分子名称: | CHENODEOXYCHOLIC ACID, Regulatory protein, SULFATE ION | | 著者 | Nakashima, R, Sakurai, K, Yamasaki, S, Nishino, K. | | 登録日 | 2018-09-13 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of the multidrug resistance regulator RamR complexed with bile acids.
Sci Rep, 9, 2019
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3VVY
 | | Crystal Strucuture of The Ethidium-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | ETHIDIUM, Putative regulatory protein | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VVX
 | | Crystal Strucuture of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW1
 | | Crystal Strucuture of the Crystal Violet-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | CHLORIDE ION, CRYSTAL VIOLET, Putative regulatory protein, ... | | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW0
 | | Crystal Structure of The Dequalinum-bound Form of RamR (Transcriptional Regulator of TetR Family) From Salmonella Typhimurium | | 分子名称: | DEQUALINIUM, Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VW2
 | | Crystal Strucuture of The Berberine-bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | BERBERINE, Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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3VVZ
 | | Crystal Strucuture of The Rhodamine 6G-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | Putative regulatory protein, RHODAMINE 6G, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
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8H4V
 | | Mincle CRD complex with PGL trisaccharide | | 分子名称: | (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol-(1-4)-6-deoxy-2,3-di-O-methyl-alpha-L-mannopyranose-(1-2)-3-O-methyl-alpha-L-rhamnopyranose, C-type lectin domain family 4 member E, CALCIUM ION | | 著者 | Ishizuka, S, Nagae, M, Yamasaki, S. | | 登録日 | 2022-10-11 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand.
Acs Cent.Sci., 9, 2023
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8HB5
 | | Crystal structure of Mincle in complex with HD-275 | | 分子名称: | (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol, C-type lectin domain family 4 member E, CALCIUM ION | | 著者 | Ishizuka, S, Nagae, M, Yamasaki, S. | | 登録日 | 2022-10-27 | | 公開日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand.
Acs Cent.Sci., 9, 2023
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8Y6X
 | | Crystal structure of ternary complex of human MR1, ligand #4, and MAIT-TCR A-F7 | | 分子名称: | 5-(2-oxidanylidenepropyl)-8-[(2~{S},3~{S},4~{R})-2,3,4,5-tetrakis(oxidanyl)pentyl]-1,7-dihydropteridine-2,4,6-trione, Beta-2-microglobulin, MAIT T cell receptor (A-F7) alpha chain, ... | | 著者 | Nagae, M, Inuki, S, Yamasaki, S. | | 登録日 | 2024-02-03 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Development of Ribityllumazine Analogue as Mucosal-Associated Invariant T Cell Ligands.
J.Am.Chem.Soc., 2024
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8W9J
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8W9H
 | | Crystal structure of anti-human CLEC12A antibody 50C1 | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, anti-human CLEC12A antibody 50C1 Fab Heavy chain, ... | | 著者 | Mori, S, Nagae, M, Yamasaki, S. | | 登録日 | 2023-09-05 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
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8W8T
 | | Crystal structure of human CLEC12A CRD | | 分子名称: | C-type lectin domain family 12 member A, SULFATE ION | | 著者 | Mori, S, Nagae, M, Yamasaki, S. | | 登録日 | 2023-09-04 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands.
Int.Immunol., 36, 2024
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6LKR
 | | Crystal structure of mouse DCAR2 CRD domain complex | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C-type lectin domain family 4, member b1, ... | | 著者 | Omahdi, Z, Horikawa, Y, Toyonaga, K, Kakuta, Y, Yamasaki, S. | | 登録日 | 2019-12-20 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
J.Biol.Chem., 295, 2020
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6KZR
 | | Crystal structure of mouse DCAR2 CRD domain | | 分子名称: | C-type lectin domain family 4, member b1, CALCIUM ION, ... | | 著者 | Omahdi, Z, Horikawa, Y, Toyonaga, K, Teramoto, T, Kakuta, Y, Yamasaki, S. | | 登録日 | 2019-09-25 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
J.Biol.Chem., 295, 2020
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6LFJ
 | | Crystal structure of mouse DCAR2 CRD domain complex with IPM2 | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, C-type lectin domain family 4, member b1, ... | | 著者 | Omahdi, Z, Horikawa, Y, Toyonaga, K, Kakuta, Y, Yamasaki, S. | | 登録日 | 2019-12-03 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
J.Biol.Chem., 295, 2020
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7EA6
 | | Crystal structure of TCR-017 ectodomain | | 分子名称: | T cell receptor 017 alpha chain, T cell receptor 017 beta chain | | 著者 | Nagae, M, Yamasaki, S. | | 登録日 | 2021-03-06 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.18000245 Å) | | 主引用文献 | Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.
J.Exp.Med., 218, 2021
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7F5K
 | | Crystal structure of TCR4-1 ectodomain | | 分子名称: | T cell receptor alpha chain, T cell receptor beta chain | | 著者 | Nagae, M, Yamasaki, S. | | 登録日 | 2021-06-22 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.0000298 Å) | | 主引用文献 | Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b.
Nat Commun, 13, 2022
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3WH2
 | | Human Mincle in complex with citrate | | 分子名称: | C-type lectin domain family 4 member E, CALCIUM ION, CITRATE ANION | | 著者 | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | | 登録日 | 2013-08-21 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WHD
 | | C-type lectin, human MCL | | 分子名称: | C-type lectin domain family 4 member D, CALCIUM ION | | 著者 | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | | 登録日 | 2013-08-24 | | 公開日 | 2013-10-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
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3WH3
 | | human Mincle, ligand free form | | 分子名称: | C-type lectin domain family 4 member E, CALCIUM ION | | 著者 | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | | 登録日 | 2013-08-21 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL
Proc.Natl.Acad.Sci.USA, 110, 2013
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6IIA
 | | MexB in complex with LMNG | | 分子名称: | Lauryl Maltose Neopentyl Glycol, Multidrug resistance protein MexB | | 著者 | Nakashima, R, Sakurai, K, Nakao, K. | | 登録日 | 2018-10-04 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds.
Sci Rep, 9, 2019
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3VW8
 | | Crystal structure of human c-Met kinase domain with its inhibitor | | 分子名称: | CHLORIDE ION, Hepatocyte growth factor receptor, N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide | | 著者 | Matsumoto, S, Miyamoto, N, Hirayama, T, Oki, H, Okada, K, Tawada, M, Iwata, H, Miki, H, Nakamura, K, Hori, A, Imamura, S. | | 登録日 | 2012-08-08 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
Bioorg.Med.Chem., 21, 2013
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1ETL
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