6GDT
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6ZDM
| Crystal structure of human heparanase in complex with a N',6O'-bis-sulfated 4-methylumbelliferyl heparan sulfate disaccharide | 分子名称: | (2~{S},3~{S},4~{R},5~{R},6~{S})-3-[(2~{R},3~{R},4~{R},5~{S},6~{R})-4,5-bis(oxidanyl)-3-(sulfoamino)-6-(sulfooxymethyl)oxan-2-yl]oxy-6-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Davies, G.J. | 登録日 | 2020-06-14 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.714 Å) | 主引用文献 | Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide. Chem.Commun.(Camb.), 56, 2020
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5LA7
| Crystal structure of human proheparanase, in complex with glucuronic acid configured aziridine probe JJB355 | 分子名称: | (1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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4JCM
| Crystal structure of Gamma-CGTASE from Alkalophilic bacillus clarkii at 1.65 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wu, L, Yang, D, Zhou, J, Wu, J, Chen, J. | 登録日 | 2013-02-22 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The Crystal Structure of Gamma-Cgtase from Alkalophilic Bacillus Clarkii at 1.65 Angstrom Resolution. To be Published
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5L9Y
| Crystal structure of human heparanase, in complex with glucuronic acid configured aziridine probe JJB355 | 分子名称: | (1~{S},2~{R},3~{S},4~{S},5~{S},6~{R})-2-(8-azidooctylamino)-3,4,5,6-tetrakis(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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5LA4
| Crystal structure of apo human proheparanase | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Heparanase, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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5L9Z
| Crystal structure of human heparanase nucleophile mutant (E343Q), in complex with unreacted glucuronic acid configured aziridine probe JJB355 | 分子名称: | (1~{R},2~{S},3~{R},4~{S},5~{S},6~{R})-7-[8-[(azanylidene-{4}-azanylidene)amino]octyl]-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, L, Jin, Y, Davies, G.J. | 登録日 | 2016-06-13 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Activity-based probes for functional interrogation of retaining beta-glucuronidases. Nat. Chem. Biol., 13, 2017
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4JCL
| Crystal structure of Alpha-CGT from Paenibacillus macerans at 1.7 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wu, L, Zhou, J, Wu, J, Li, J, Chen, J. | 登録日 | 2013-02-22 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Alpha-Cgt from Paenibacillus Macerans at 1.7 Angstrom Resolution To be Published
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3PVL
| Structure of myosin VIIa MyTH4-FERM-SH3 in complex with the CEN1 of Sans | 分子名称: | GLYCEROL, Myosin VIIa isoform 1, PHOSPHATE ION, ... | 著者 | Wu, L, Pan, L.F, Wei, Z.Y, Zhang, M.J. | 登録日 | 2010-12-07 | 公開日 | 2011-03-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo. Science, 331, 2011
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5GKW
| crystal structure of SZ529 complex with (R,R)-cyclopentanediol | 分子名称: | (1~{R},2~{R})-cyclopentane-1,2-diol, Limonene-1,2-epoxide hydrolase | 著者 | Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H. | 登録日 | 2016-07-07 | 公開日 | 2017-07-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | crystal structure of SZ529 complex with (R,R)-cyclopentanediol To Be Published
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5CK6
| Crystal structure of SZ348 in complex with cyclopentene oxide | 分子名称: | (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, NICKEL (II) ION, ... | 著者 | Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H. | 登録日 | 2015-07-15 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of SZ348 in complex with cyclopentene oxide To Be Published
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5CLK
| Crystal structure of SZ348 in complex with S,S-cyclohexanediol | 分子名称: | (1S,2S)-cyclohexane-1,2-diol, CHLORIDE ION, Limonene-1,2-epoxide hydrolase, ... | 著者 | Wu, L, Sun, Z.T, Reetz, M.T, Zhou, J.H. | 登録日 | 2015-07-16 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Crystal structure of SZ348 in complex with S,S-cyclohexanediol To Be Published
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5CF2
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5E98
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5E9B
| Crystal structure of human heparanase in complex with HepMer M09S05a | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, CHLORIDE ION, ... | 著者 | Wu, L, Davies, G.J. | 登録日 | 2015-10-14 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22, 2015
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5E9C
| Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wu, L, Davies, G.J. | 登録日 | 2015-10-15 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22, 2015
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5E8M
| Crystal structure of human heparanase | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wu, L, Davies, G.J. | 登録日 | 2015-10-14 | 公開日 | 2015-11-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22, 2015
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5E97
| Glycoside Hydrolase ligand structure 1 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wu, L, Davies, G.J. | 登録日 | 2015-10-14 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22, 2015
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5D74
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5D76
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5CF1
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6KVY
| The structure of EanB/T414A complex with hercynine | 分子名称: | CHLORIDE ION, MAGNESIUM ION, N,N,N-trimethyl-histidine, ... | 著者 | Wu, L, Liu, P.H, Zhou, J.H. | 登録日 | 2019-09-05 | 公開日 | 2020-09-09 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | The structure of EanB/T414A complex with hercynine To Be Published
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6KW0
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6KVZ
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6KVW
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