6ZDM
Crystal structure of human heparanase in complex with a N',6O'-bis-sulfated 4-methylumbelliferyl heparan sulfate disaccharide
This is a non-PDB format compatible entry.
Summary for 6ZDM
Entry DOI | 10.2210/pdb6zdm/pdb |
Descriptor | Heparanase, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | heparanase, substrate, fluorogenic, heparan sulfate, poised, 4-methylumbelliferyl, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 53713.26 |
Authors | Wu, L.,Davies, G.J. (deposition date: 2020-06-14, release date: 2020-10-21, Last modification date: 2024-01-24) |
Primary citation | Wu, L.,Wimmer, N.,Davies, G.J.,Ferro, V. Structural insights into heparanase activity using a fluorogenic heparan sulfate disaccharide. Chem.Commun.(Camb.), 56:13780-13783, 2020 Cited by PubMed: 33073275DOI: 10.1039/d0cc05932c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.714 Å) |
Structure validation
Download full validation report