2JR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jr7 by Molmil](/molmil-images/mine/2jr7) | |
3OF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3of7 by Molmil](/molmil-images/mine/3of7) | The Crystal Structure of Prp20p from Saccharomyces cerevisiae and Its Binding Properties to Gsp1p and Histones | 分子名称: | Regulator of chromosome condensation | 著者 | Wu, F, Liu, Y, Zhu, Z, Huang, H, Ding, B, Wu, J, Shi, Y. | 登録日 | 2010-08-14 | 公開日 | 2011-03-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The 1.9A crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones. J.Struct.Biol., 174, 2011
|
|
6LN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ln2 by Molmil](/molmil-images/mine/6ln2) | Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab7F38_heavy chain, Fab7F38_light chain, ... | 著者 | Wu, F, Yang, L, Hang, K, Laursen, M, Wu, L, Han, G.W, Ren, Q, Roed, N.K, Lin, G, Hanson, M, Jiang, H, Wang, M, Reedtz-Runge, S, Song, G, Stevens, R.C. | 登録日 | 2019-12-28 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Full-length human GLP-1 receptor structure without orthosteric ligands. Nat Commun, 11, 2020
|
|
5J3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5j3j by Molmil](/molmil-images/mine/5j3j) | Crystal Structure of human DPP-IV in complex with HL1 | 分子名称: | (2~{S},3~{R})-8,9-dimethoxy-3-[2,4,5-tris(fluoranyl)phenyl]-2,3-dihydro-1~{H}-benzo[f]chromen-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | 著者 | Wu, F, Li, H, Zhao, Z, Zhu, L, Xu, H, Li, S. | 登録日 | 2016-03-31 | 公開日 | 2017-04-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structure of human DPP-IV in complex with HL1 To Be Published
|
|
3V1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v1s by Molmil](/molmil-images/mine/3v1s) | Scaffold tailoring by a newly detected Pictet-Spenglerase ac-tivity of strictosidine synthase (STR1): from the common tryp-toline skeleton to the rare piperazino-indole framework | 分子名称: | 2-(1H-indol-1-yl)ethanamine, Strictosidine synthase | 著者 | Wu, F, Zhu, H, Sun, L, Rajendran, C, Wang, M, Ren, X, Panjikar, S, Cherkasov, A, Zou, H, Stoeckigt, J. | 登録日 | 2011-12-10 | 公開日 | 2012-02-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.328 Å) | 主引用文献 | Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework J.Am.Chem.Soc., 134, 2012
|
|
1TXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1txc by Molmil](/molmil-images/mine/1txc) | |
1TW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tw0 by Molmil](/molmil-images/mine/1tw0) | |
6L9I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l9i by Molmil](/molmil-images/mine/6l9i) | |
7ZVD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zvd by Molmil](/molmil-images/mine/7zvd) | K89 acetylated glucose-6-phosphate dehydrogenase (G6PD) in a complex with structural NADP+ | 分子名称: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wu, F, Muskat, N.H, Nudelman, H, Shahar, A, Arbely, E. | 登録日 | 2022-05-15 | 公開日 | 2023-08-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Acetylation-dependent coupling between G6PD activity and apoptotic signaling. Nat Commun, 14, 2023
|
|
7ZVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zve by Molmil](/molmil-images/mine/7zve) | K403 acetylated glucose-6-phosphate dehydrogenase (G6PD) | 分子名称: | COPPER (II) ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase | 著者 | Wu, F, Muskat, N.H, Shahar, A, Arbely, E. | 登録日 | 2022-05-15 | 公開日 | 2023-08-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Acetylation-dependent coupling between G6PD activity and apoptotic signaling. Nat Commun, 14, 2023
|
|
5E6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e6o by Molmil](/molmil-images/mine/5e6o) | Crystal structure of C. elegans LGG-2 bound to an AIM/LIR motif | 分子名称: | Protein lgg-2, TRP-GLU-GLU-LEU | 著者 | Qi, X, Ren, J.Q, Wu, F, Zhang, H, Feng, W. | 登録日 | 2015-10-10 | 公開日 | 2016-01-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy Mol.Cell, 60, 2015
|
|
5E6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e6n by Molmil](/molmil-images/mine/5e6n) | Crystal structure of C. elegans LGG-2 | 分子名称: | Protein lgg-2 | 著者 | Qi, X, Ren, J.Q, Wu, F, Zhang, H, Feng, W. | 登録日 | 2015-10-10 | 公開日 | 2016-01-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy Mol.Cell, 60, 2015
|
|
5EGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5egg by Molmil](/molmil-images/mine/5egg) | |
4XS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xs3 by Molmil](/molmil-images/mine/4xs3) | Crystal structure of a metabolic reductase with (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one | 分子名称: | (E)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y. | 登録日 | 2015-01-21 | 公開日 | 2016-07-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.291 Å) | 主引用文献 | Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds. J.Med.Chem., 58, 2015
|
|
4XRX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xrx by Molmil](/molmil-images/mine/4xrx) | Crystal structure of a metabolic reductase with (E)-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one | 分子名称: | 5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y. | 登録日 | 2015-01-21 | 公開日 | 2015-12-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds. J.Med.Chem., 58, 2015
|
|
5X0S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x0s by Molmil](/molmil-images/mine/5x0s) | Solution NMR structure of peptide toxin SsTx from Scolopendra subspinipes mutilans | 分子名称: | SsTx | 著者 | Wu, F, Luo, L, Qu, D, Zhang, L, Tian, C, Lai, R. | 登録日 | 2017-01-23 | 公開日 | 2018-01-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Centipedes subdue giant prey by blocking KCNQ channels Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
2M9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m9m by Molmil](/molmil-images/mine/2m9m) | Solution Structure of ERCC4 domain of human FAAP24 | 分子名称: | Fanconi anemia-associated protein of 24 kDa | 著者 | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | 登録日 | 2013-06-18 | 公開日 | 2013-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
|
|
2M9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m9n by Molmil](/molmil-images/mine/2m9n) | Solution Structure of (HhH)2 domain of human FAAP24 | 分子名称: | Fanconi anemia-associated protein of 24 kDa | 著者 | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | 登録日 | 2013-06-18 | 公開日 | 2013-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
|
|
2MVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mvt by Molmil](/molmil-images/mine/2mvt) | Solution structure of scoloptoxin SSD609 from Scolopendra mutilans | 分子名称: | Scoloptoxin SSD609 | 著者 | Wu, F, Sun, P, Wang, C, He, Y, Zhang, L, Tian, C. | 登録日 | 2014-10-14 | 公開日 | 2015-09-23 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A distinct three-helix centipede toxin SSD609 inhibits Iks channels by interacting with the KCNE1 auxiliary subunit. Sci Rep, 5, 2015
|
|
6MO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mo2 by Molmil](/molmil-images/mine/6mo2) | Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | 分子名称: | 1-(4-{5-[(piperidin-4-yl)methoxy]-3-[4-(1H-pyrazol-4-yl)phenyl]pyrazin-2-yl}phenyl)methanamine, FLAVIVIRUS_NS2B/Peptidase S7 | 著者 | Lin, Y.-L, Nie, S, Hua, Y, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | 登録日 | 2018-10-03 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J.Am.Chem.Soc., 141, 2019
|
|
1YOP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yop by Molmil](/molmil-images/mine/1yop) | The solution structure of Kti11p | 分子名称: | Kti11p, ZINC ION | 著者 | Sun, J, Zhang, J, Wu, F, Xu, C, Li, S, Zhao, W, Wu, Z, Wu, J, Zhou, C.-Z, Shi, Y. | 登録日 | 2005-01-28 | 公開日 | 2005-04-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module. Biochemistry, 44, 2005
|
|
5VEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vex by Molmil](/molmil-images/mine/5vex) | Structure of the human GLP-1 receptor complex with NNC0640 | 分子名称: | 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide, Glucagon-like peptide 1 receptor, Endolysin chimera | 著者 | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | 登録日 | 2017-04-05 | 公開日 | 2017-05-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
|
|
5VEW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vew by Molmil](/molmil-images/mine/5vew) | Structure of the human GLP-1 receptor complex with PF-06372222 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, ... | 著者 | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | 登録日 | 2017-04-05 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
|
|
6JXM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jxm by Molmil](/molmil-images/mine/6jxm) | Crystal Structure of phi29 pRNA domain II | 分子名称: | BARIUM ION, MAGNESIUM ION, RNA (97-mer) | 著者 | Cai, R, Price, I.R, Ding, F, Wu, F, Chen, T, Zhang, Y, Liu, G, Jardine, P.J, Lu, C, Ke, A. | 登録日 | 2019-04-24 | 公開日 | 2019-08-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | ATP/ADP modulates gp16-pRNA conformational change in the Phi29 DNA packaging motor. Nucleic Acids Res., 47, 2019
|
|
6MO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mo1 by Molmil](/molmil-images/mine/6mo1) | Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | 分子名称: | 5-[4-(aminomethyl)phenyl]-6-[4-(furan-3-yl)phenyl]-N-[(piperidin-4-yl)methyl]pyrazin-2-amine, FLAVIVIRUS_NS2B/Peptidase S7 | 著者 | Lin, Y.-L, Hua, Y, Nie, S, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | 登録日 | 2018-10-03 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J.Am.Chem.Soc., 141, 2019
|
|