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2N9W
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Solution NMR Structure of the membrane localization domain from the Ras/Rap1-specific endopeptidase (RRSP) of the Vibrio vulnificus multifunctional autoprocessing repeats-in-toxins (MARTX) toxin
分子名称: RTX toxin
著者Hisao, G.S, Brothers, M.C, Ho, M, Wilson, B.A, Rienstra, C.M.
登録日2015-12-12
公開日2016-12-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution.
Protein Sci., 26, 2017
2N9V
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Solution NMR Structure of the membrane localization domain from Pasteurella multocida toxin
分子名称: Dermonecrotic toxin
著者Hisao, G.S, Brothers, M.C, Ho, M, Wilson, B.A, Rienstra, C.M.
登録日2015-12-12
公開日2016-12-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution.
Protein Sci., 26, 2017
8FE5
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Structure of J-PKAc chimera complexed with Aplithianine B
分子名称: 6-[(6P)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7,9-dihydro-8H-purin-8-one, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
登録日2022-12-05
公開日2023-10-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
8FEC
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BU of 8fec by Molmil
Structure of J-PKAc chimera complexed with Aplithianine derivative
分子名称: 6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
著者Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
登録日2022-12-06
公開日2023-10-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
8FE2
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Structure of J-PKAc chimera complexed with Aplithianine A
分子名称: 6-[(6M)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-9H-purine, DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Du, L, Wilson, B.A.P, Li, N, Dalilian, M, Wang, D, Martinez Fiesco, J.A, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R.
登録日2022-12-05
公開日2023-10-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J.Nat.Prod., 86, 2023
3K3Q
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Crystal Structure of a Llama Antibody complexed with the C. Botulinum Neurotoxin Serotype A Catalytic Domain
分子名称: Botulinum neurotoxin type A, ZINC ION, llama Aa1 VHH domain
著者Thompson, A.A, Dong, J, Marks, J.D, Stevens, R.C.
登録日2009-10-04
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic alpha-Exosite Binding Region.
J.Mol.Biol., 397, 2010
6XN9
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Solution NMR structure of recifin, a cysteine-rich tyrosyl-DNA Phosphodiesterase I modulatory peptide from the marine sponge Axinella sp.
分子名称: Recifin modulatory peptide
著者Schroeder, C.I, Rosengren, K.J, O'Keefe, B.R.
登録日2020-07-02
公開日2021-02-10
実験手法SOLUTION NMR
主引用文献Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.
J.Am.Chem.Soc., 142, 2020

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