1AMK
 
 | | LEISHMANIA MEXICANA TRIOSE PHOSPHATE ISOMERASE | | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, TRIOSE PHOSPHATE ISOMERASE | | 著者 | Williams, J.C, Wierenga, R. | | 登録日 | 1997-06-17 | | 公開日 | 1997-12-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power.
Protein Eng., 12, 1999
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2PTK
 | | CHICKEN SRC TYROSINE KINASE | | 分子名称: | TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC | | 著者 | Williams, J.C, Wierenga, R. | | 登録日 | 1997-06-17 | | 公開日 | 1997-12-24 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions
J.Mol.Biol., 274, 1997
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1WP0
 | | Human SCO1 | | 分子名称: | SCO1 protein homolog | | 著者 | Williams, J.C, Sue, C, Banting, G.S, Yang, H, Glerum, D.M, Hendrickson, W.A, Schon, E.A. | | 登録日 | 2004-08-27 | | 公開日 | 2005-01-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Human SCO1: IMPLICATIONS FOR REDOX SIGNALING BY A MITOCHONDRIAL CYTOCHROME c OXIDASE "ASSEMBLY" PROTEIN
J.Biol.Chem., 280, 2005
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1YGT
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2PG1
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5U5M
 | | CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-MEDITOPE | | 分子名称: | AZIDO-PEG4-MEDITOPE, Immunoglobulin G binding protein A, MEMAB TRASTUZUMAB, ... | | 著者 | Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D. | | 登録日 | 2016-12-06 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-Meditope
To Be Published
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5U6A
 | | CRYSTAL STRUCTURE OF I83E MEDITOPE-ENABLED TRASTUZUMAB WITH AZIDO-PEG3-MEDITOPE | | 分子名称: | Heavy Chain, Immunoglobulin G binding protein A, Light Chain, ... | | 著者 | Williams, J.C, Bzymek, K.P, Pucket, J, Avery, K.A, Ma, Y, Xie, J, Zer, C, Horne, D. | | 登録日 | 2016-12-07 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.736 Å) | | 主引用文献 | Crystal Structure Of I83E Meditope-Enabled Trastuzumab With Azido-PEG3-Meditope
To Be Published
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8G2M
 | | The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer | | 分子名称: | CITRIC ACID, Heavy chain of humanized IgG, Light chain of humanized IgG, ... | | 著者 | Williams, J.C, Williams, J.C. | | 登録日 | 2023-02-05 | | 公開日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.
J Immunother Cancer, 11, 2023
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8G8N
 | | CTLA4 Fab with peptide | | 分子名称: | CYS-PRO-GLY-LYS-GLY-LEU-PRO-SER-CYS, Fab heavy chain, Fab light chain | | 著者 | Williams, J.C. | | 登録日 | 2023-02-18 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | XTX101, a tumor-activated, Fc-enhanced anti-CTLA-4 monoclonal antibody, demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer.
J Immunother Cancer, 11, 2023
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3GC3
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5IV2
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5IVZ
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6AYN
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6AZK
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6AU5
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6AXP
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6BAH
 | | Trastuzumab Fab v3 with 5-diphenyl meditope variant | | 分子名称: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain,IGH@ protein, ... | | 著者 | Bzymek, K.P, King, J.D, Williams, J.C. | | 登録日 | 2017-10-12 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
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6B9Z
 | | Trastuzumab Fab v3 | | 分子名称: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | | 著者 | Bzymek, K.P, King, J.D, Williams, J.C. | | 登録日 | 2017-10-11 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
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6B9Y
 | | Trastuzumab Fab v3 in complex with 5-phenyl meditope variant | | 分子名称: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | | 著者 | Bzymek, K.P, King, J.D, Williams, J.C. | | 登録日 | 2017-10-11 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
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6AZL
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6BAE
 | | Trastuzumab Fab v3 in complex with CQFDLSTRRLKC | | 分子名称: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | | 著者 | Bzymek, K.P, King, J.D, Williams, J.C. | | 登録日 | 2017-10-12 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Bioconjug. Chem., 29, 2018
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1JDL
 | | Structure of cytochrome c2 from Rhodospirillum Centenum | | 分子名称: | CYTOCHROME C2, ISO-2, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Camara-Artigas, A, Williams, J.C, Allen, J.P. | | 登録日 | 2001-06-14 | | 公開日 | 2001-11-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of cytochrome c2 from Rhodospirillum centenum.
Acta Crystallogr.,Sect.D, 57, 2001
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2M02
 | | 3D structure of cap-gly domain of mammalian dynactin determined by magic angle spinning NMR spectroscopy | | 分子名称: | Dynactin subunit 1 | | 著者 | Yan, S, Hou, G, Schwieters, C.D, Ahmed, S, Williams, J.C, Polenova, T. | | 登録日 | 2012-10-15 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End-Binding Protein EB1.
J.Mol.Biol., 425, 2013
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4Y1L
 | | Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation | | 分子名称: | RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9 | | 著者 | Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y. | | 登録日 | 2015-02-08 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
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3DVT
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