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8ASG
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BU of 8asg by Molmil
Structure of the SFTSV L protein bound in a resting state [RESTING]
分子名称: MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*AP*UP*GP*A*)-3'), RNA (5'-R(*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U*)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2022-08-19
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
8ASB
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BU of 8asb by Molmil
Structure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a raised conformation [EARLY-ELONGATION-ENDO]
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*A)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2022-08-18
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
8ASD
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BU of 8asd by Molmil
Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION]
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2022-08-19
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
8AS6
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BU of 8as6 by Molmil
Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK]
分子名称: RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*C)-3'), RNA-dependent RNA-polymerase L protein
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2022-08-18
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
8AS7
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BU of 8as7 by Molmil
Structure of the SFTSV L protein stalled at early elongation [EARLY-ELONGATION]
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2022-08-18
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
8R6W
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BU of 8r6w by Molmil
Structure of the SFTSV L protein in a transcription-priming state with bound capped RNA [TRANSCRIPTION-PRIMING]
分子名称: RNA (5'-R(*(M7G)*AP*AP*A)-3'), RNA (5'-R(*AP*CP*AP*C)-3'), RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*G)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Busch, C, Milewski, M, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-11-23
公開日2024-04-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural snapshots of phenuivirus cap-snatching and transcription.
Nucleic Acids Res., 52, 2024
8R6Y
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BU of 8r6y by Molmil
Structure of the SFTSV L protein stalled in a transcription-specific early elongation state with bound capped RNA [TRANSCRIPTION-EARLY-ELONGATION]
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(*(M7G)*AP*AP*A)-3'), ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Busch, C, Milewski, M, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-11-23
公開日2024-04-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural snapshots of phenuivirus cap-snatching and transcription.
Nucleic Acids Res., 52, 2024
8R6U
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BU of 8r6u by Molmil
Structure of the SFTSV L protein in a transcription-priming state without capped RNA [TRANSCRIPTION-PRIMING (in vitro)]
分子名称: MAGNESIUM ION, RNA (5'-R(P*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), RNA primer, ...
著者Williams, H.M, Thorkelsson, S.R, Vogel, D, Busch, C, Milewski, M, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
登録日2023-11-23
公開日2024-04-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structural snapshots of phenuivirus cap-snatching and transcription.
Nucleic Acids Res., 52, 2024
6ZR4
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BU of 6zr4 by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1
分子名称: ACETIC ACID, CALCIUM ION, Fibrinogen C domain-containing protein 1, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
6ZR3
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BU of 6zr3 by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with N-acetyl-galactosamine-4-sulfate ligand bound
分子名称: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, ACETIC ACID, CALCIUM ION, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
6ZQR
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BU of 6zqr by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with GlcNAc ligand bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
6ZQX
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BU of 6zqx by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with N,N'-diacetyl chitobiose ligand bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
6ZR0
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BU of 6zr0 by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with N-acetylalanine ligand bound
分子名称: ACETIC ACID, CALCIUM ION, Fibrinogen C domain-containing protein 1, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
6ZQY
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BU of 6zqy by Molmil
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with Neu5Ac ligand bound
分子名称: ACETIC ACID, CALCIUM ION, Fibrinogen C domain-containing protein 1, ...
著者Shrive, A.K, Greenhough, T.J, Williams, H.M.
登録日2020-07-10
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
7OE7
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BU of 7oe7 by Molmil
Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-01
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OJK
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BU of 7ojk by Molmil
Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER]
分子名称: 3' RNA, 5' RNA, RNA-directed RNA polymerase L, ...
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-16
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OCH
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BU of 7och by Molmil
Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-04-26
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OEA
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BU of 7oea by Molmil
Lassa virus L protein bound to 3' promoter RNA (well-resolved polymerase core) [3END-CORE]
分子名称: 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ...
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-02
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OJN
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BU of 7ojn by Molmil
Lassa virus L protein in an elongation conformation [ELONGATION]
分子名称: 3' RNA, 5' RNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-16
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OEB
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BU of 7oeb by Molmil
Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO]
分子名称: 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ...
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-02
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OE3
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BU of 7oe3 by Molmil
Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-01
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OJL
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BU of 7ojl by Molmil
Lassa virus L protein in a pre-initiation conformation [PREINITIATION]
分子名称: 3' RNA, 5' RNA, MANGANESE (II) ION, ...
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-16
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
7OJJ
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BU of 7ojj by Molmil
Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK]
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION
著者Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S.
登録日2021-05-16
公開日2021-12-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021

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件を2024-07-24に公開中

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