8C61
 
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1Y08
 | | Structure of the Streptococcal Endopeptidase IdeS, a Novel Cysteine Proteinase with Strict Specificity for IgG | | 分子名称: | SULFATE ION, hypothetical protein SPy0861 | | 著者 | Wenig, K, Chatwell, L, von Pawel-Rammingen, U, Bjoerck, L, Huber, R, Sondermann, P. | | 登録日 | 2004-11-15 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG
Proc.Natl.Acad.Sci.Usa, 101, 2004
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6OLA
 | | Structure of the PCV2d virus-like particle | | 分子名称: | Capsid protein, DNA (5'-D(P*CP*CP*GP*G)-3') | | 著者 | Khayat, R, Wen, K, Alimova, A, Galarza, J, Gottlieb, P. | | 登録日 | 2019-04-16 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural characterization of the PCV2d virus-like particle at 3.3 angstrom resolution reveals differences to PCV2a and PCV2b capsids, a tetranucleotide, and an N-terminus near the icosahedral 3-fold axes.
Virology, 537, 2019
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5CP7
 | | Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides | | 分子名称: | Heavy Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7, Light Chain of Antigen-Binding Fragment of Monoclonal Antibody of 4C7 | | 著者 | Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X. | | 登録日 | 2015-07-21 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
Anal. Chem., 91, 2019
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5CP3
 | | Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides in Complex with Sulfathiazole | | 分子名称: | 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, CALCIUM ION, GLYCEROL, ... | | 著者 | Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X. | | 登録日 | 2015-07-21 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
Anal. Chem., 91, 2019
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1XMK
 | | The Crystal structure of the Zb domain from the RNA editing enzyme ADAR1 | | 分子名称: | CADMIUM ION, CHLORIDE ION, Double-stranded RNA-specific adenosine deaminase, ... | | 著者 | Athanasiadis, A, Placido, D, Maas, S, Brown II, B.A, Lowenhaupt, K, Rich, A. | | 登録日 | 2004-10-03 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | | 主引用文献 | The Crystal Structure of the Z[beta] Domain of the RNA-editing Enzyme ADAR1 Reveals Distinct Conserved Surfaces Among Z-domains.
J.Mol.Biol., 351, 2005
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2BA1
 | | Archaeal exosome core | | 分子名称: | Archaeal exosome RNA binding protein CSL4, Archaeal exosome complex exonuclease RRP41, Archaeal exosome complex exonuclease RRP42, ... | | 著者 | Hopfner, K.P, Buttner, K, Wenig, K. | | 登録日 | 2005-10-13 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural framework for the mechanism of archaeal exosomes in RNA processing.
Mol.Cell, 20, 2005
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2BA0
 | | Archaeal exosome core | | 分子名称: | Archaeal exosome RNA binding protein RRP4, Archaeal exosome RNA binding protein RRP41, Archaeal exosome RNA binding protein RRP42 | | 著者 | Buttner, K, Wenig, K, Hopfner, K.P. | | 登録日 | 2005-10-13 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural framework for the mechanism of archaeal exosomes in RNA processing.
Mol.Cell, 20, 2005
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1OYI
 | | Solution structure of the Z-DNA binding domain of the vaccinia virus gene E3L | | 分子名称: | double-stranded RNA-binding protein | | 著者 | Kahmann, J.D, Wecking, D.A, Putter, V, Lowenhaupt, K, Kim, Y.-G, Schmieder, P, Oschkinat, H, Rich, A, Schade, M. | | 登録日 | 2003-04-04 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro.
Proc.Natl.Acad.Sci.USA, 101, 2004
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8SWK
 | | Cryo-EM structure of NLRP3 closed hexamer | | 分子名称: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ... | | 著者 | Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. | | 登録日 | 2023-05-18 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | | 主引用文献 | Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
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8SXN
 | | Structure of NLRP3 and NEK7 complex | | 分子名称: | 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-TRIPHOSPHATE, NACHT, ... | | 著者 | Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. | | 登録日 | 2023-05-22 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | | 主引用文献 | Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
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8SWF
 | | Cryo-EM structure of NLRP3 open octamer | | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | | 著者 | Yu, X, Matico, R.E, Miller, R, Schoubroeck, B.V, Grauwen, K, Suarez, J, Pietrak, B, Haloi, N, Yin, Y, Tresadern, G.J, Perez-Benito, L, Lindahl, E, Bottelbergs, A, Oehlrich, D, Opdenbosch, N.V, Sharma, S. | | 登録日 | 2023-05-18 | | 公開日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Cryo-EM structures of NLRP3 reveal its self-activation mechanism
Nat Commun, 2024
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1QGP
 | | NMR STRUCTURE OF THE Z-ALPHA DOMAIN OF ADAR1, 15 STRUCTURES | | 分子名称: | PROTEIN (DOUBLE STRANDED RNA ADENOSINE DEAMINASE) | | 著者 | Schade, M, Turner, C.J, Kuehne, R, Schmieder, P, Lowenhaupt, K, Herbert, A, Rich, A, Oschkinat, H. | | 登録日 | 1999-05-03 | | 公開日 | 1999-10-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
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2ACJ
 | | Crystal structure of the B/Z junction containing DNA bound to Z-DNA binding proteins | | 分子名称: | 5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*GP*GP*CP*GP*CP*GP*CP*G)-3', 5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*CP*AP*TP*AP*AP*AP*CP*C)-3', Double-stranded RNA-specific adenosine deaminase | | 著者 | Ha, S.C, Lowenhaupt, K, Rich, A, Kim, Y.-G, Kim, K.K. | | 登録日 | 2005-07-19 | | 公開日 | 2005-10-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a junction between B-DNA and Z-DNA reveals two extruded bases.
Nature, 437, 2005
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1SFU
 | | Crystal structure of the viral Zalpha domain bound to left-handed Z-DNA | | 分子名称: | 34L protein, 5'-D(*T*CP*GP*CP*GP*CP*G)-3' | | 著者 | Ha, S.C, Van Quyen, D, Wu, C.A, Lowenhaupt, K, Rich, A, Kim, Y.G, Kim, K.K. | | 登録日 | 2004-02-20 | | 公開日 | 2004-08-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zalpha bound to DNA.
Proc.Natl.Acad.Sci.USA, 101, 2004
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2B2N
 | | Structure of transcription-repair coupling factor | | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SODIUM ION, SULFATE ION, ... | | 著者 | Assenmacher, N, Wenig, K, Lammens, A, Hopfner, K.-P. | | 登録日 | 2005-09-19 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs
J.Mol.Biol., 355, 2006
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1J75
 | | Crystal Structure of the DNA-Binding Domain Zalpha of DLM-1 Bound to Z-DNA | | 分子名称: | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Tumor Stroma and Activated Macrophage Protein DLM-1 | | 著者 | Schwartz, T, Behlke, J, Lowenhaupt, K, Heinemann, U, Rich, A. | | 登録日 | 2001-05-15 | | 公開日 | 2001-09-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins.
Nat.Struct.Biol., 8, 2001
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6IS2
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6IS4
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6IS1
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6IS3
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6LUS
 | | Crystal structure of the Mengla Virus VP30 C-terminal domain | | 分子名称: | Minor nucleoprotein VP30 | | 著者 | Dong, S.S, Wen, K.N, Chu, H.G, Wang, C.H, Qin, X.C. | | 登録日 | 2020-01-30 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of the Mengla virus VP30 C-terminal domain.
Biochem.Biophys.Res.Commun., 525, 2020
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7N8T
 | | Crystal Structure of AMP-bound Human JNK2 | | 分子名称: | ADENOSINE MONOPHOSPHATE, HEXAETHYLENE GLYCOL, Mitogen-activated protein kinase 9 | | 著者 | Li, L, Gurbani, D, Westover, K.D. | | 登録日 | 2021-06-15 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
J.Med.Chem., 66, 2023
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8ELC
 | | Human JNK2 bound to covalent inhibitor YL2056 | | 分子名称: | 4-(dimethylamino)-N-{4-[(3S)-3-({4-[(8R)-2-phenylpyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-yl}amino)pyrrolidine-1-carbonyl]phenyl}butanamide, Mitogen-activated protein kinase 9 | | 著者 | Li, L, Gurbani, D, Westover, K.D. | | 登録日 | 2022-09-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.072 Å) | | 主引用文献 | Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1.
J.Med.Chem., 66, 2023
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5EBI
 | | Crystal structure of a DNA-RNA chimera in complex with Ba2+ ions: a case of unusual multi-domain twinning | | 分子名称: | BARIUM ION, DNA/RNA (5'-D(*C)-R(P*G)-D(P*C)-R(P*G)-D(P*C)-R(P*G)-3') | | 著者 | Gilski, M, Drozdzal, P, Kierzek, R, Jaskolski, M. | | 登録日 | 2015-10-19 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Atomic resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba(2+) ions: a case of complicated multi-domain twinning.
Acta Crystallogr D Struct Biol, 72, 2016
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