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4UU9
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BU of 4uu9 by Molmil
Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody
分子名称: COMPLEMENT C5, MEDI7814, SULFATE ION
著者Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T.
登録日2014-07-25
公開日2015-08-12
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
MAbs, 10, 2018
5UMI
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BU of 5umi by Molmil
Clostridium difficile TcdA-CROPs bound to PA50 Fab
分子名称: PA50 Fab Heavy chain, PA50 Fab Light chain, Toxin A
著者Kroh, H.K, Chandrasekaran, R, Rosenthal, K, Woods, R, Jin, X, Ohi, M.D, Nyborg, A.C, Rainey, G.J, Warrener, P, Spiller, B.W, Lacy, D.B.
登録日2017-01-27
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface.
J. Biol. Chem., 292, 2017
6CYF
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BU of 6cyf by Molmil
PcrV fragment with bound Fab
分子名称: IgG1 antibody, heavy chain fragment, kappa light chain, ...
著者Oganesyan, V.
登録日2018-04-05
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates.
J. Infect. Dis., 218, 2018
5VQM
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BU of 5vqm by Molmil
Clostridium difficile TcdB-GTD bound to PA41 Fab
分子名称: PA41 FAB HEAVY CHAIN, PA41 FAB LIGHT CHAIN, Toxin B
著者Kroh, H.K, Spiller, B.W, Lacy, D.B.
登録日2017-05-09
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.
J. Biol. Chem., 293, 2018

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件を2024-07-17に公開中

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