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Solution structure of p45 Death Domain
分子名称:	Death domain containing membrane protein NRADD
著者	Vilar, M, Sung, T.C, Lee, K.F, Riek, R.
登録日	2006-09-08
公開日	2007-10-23
最終更新日	2024-05-29
実験手法	SOLUTION NMR
主引用文献	Solution Structure of p45 death domain To be Published

7O05

Crystal structure of SARS-CoV-2 N-CTD
分子名称:	Nucleoprotein
著者	Ciges-Tomas, J.R, Vilar, M.
登録日	2021-03-25
公開日	2022-04-13
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (1.94 Å)
主引用文献	Identification of a guanine-specific pocket in the protein N of SARS-CoV-2. Commun Biol, 5, 2022

7O36

Crystal Structure of SARS-CoV-2 N-CTD in complex with GTP (II)
分子名称:	GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, Nucleoprotein
著者	Ciges-Tomas, J.R, Vilar, M.
登録日	2021-04-01
公開日	2022-04-13
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Identification of a guanine-specific pocket in the protein N of SARS-CoV-2. Commun Biol, 5, 2022

7O35

Crystal Structure of SARS-CoV-2 N-CTD in complex with GTP (I)
分子名称:	GUANOSINE-5'-TRIPHOSPHATE, Nucleoprotein
著者	Ciges-Tomas, J.R, Vilar, M.
登録日	2021-04-01
公開日	2022-04-13
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Identification of a guanine-specific pocket in the protein N of SARS-CoV-2. Commun Biol, 5, 2022

2Q9M

4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity
分子名称:	(1R,4S,7AS)-1-(1-FORMYLPROP-1-EN-1-YL)-4-METHOXY-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase
著者	Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T.
登録日	2007-06-13
公開日	2007-08-21
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity J.Med.Chem., 50, 2007

2Q9N

4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity
分子名称:	(1S,4R,7AR)-4-BUTOXY-1-[(1R)-1-FORMYLPROPYL]-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase
著者	Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T.
登録日	2007-06-13
公開日	2007-08-21
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity J.Med.Chem., 50, 2007

8PBG

Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
分子名称:	5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.46 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBP

Mutant R1785C of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.54 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBE

Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称:	CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.71 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBI

Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
分子名称:	5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBM

Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
分子名称:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.28 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBQ

Mutant R1810Q of the dihydroorotase domain of human CAD protein bound to the substrates
分子名称:	CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.54 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBR

Mutant R1475Q of the dihydroorotase domain of human CAD protein in apo form
分子名称:	CAD protein, FORMIC ACID, ZINC ION
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.06 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBJ

Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称:	CAD protein, FORMIC ACID, GLYCEROL, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.55 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBN

Mutant R1789Q of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
分子名称:	5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.71 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBT

Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the substrate dihydroorotate
分子名称:	(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.43 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBU

Mutant K1482M of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
分子名称:	5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.67 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBH

Mutant R1617Q of the dihydroorotase domain of human CAD protein bound to the substrate carbamoyl aspartate
分子名称:	CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.87 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBK

Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate
分子名称:	5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.69 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

8PBS

Mutant K1482M of the dihydroorotase domain of human CAD protein in apo form
分子名称:	CAD protein, FORMIC ACID, GLYCEROL, ...
著者	del Cano-Ochoa, F, Ramon-Maiques, S.
登録日	2023-06-09
公開日	2023-11-01
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Beyond genetics: Deciphering the impact of missense variants in CAD deficiency. J Inherit Metab Dis, 46, 2023

2MJO

NMR structure of p75 transmembrane domain C257A mutant in DPC micelles
分子名称:	Tumor necrosis factor receptor superfamily member 16
著者	Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
登録日	2014-01-15
公開日	2015-01-28
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Structural Basis of p75 Transmembrane Domain Dimerization. J. Biol. Chem., 291, 2016

2MIC

NMR structure of p75 transmembrane domain in DPC micelles
分子名称:	Tumor necrosis factor receptor superfamily member 16
著者	Nadezhdin, K, Arseniev, A, Goncharuk, S, Mineev, K.
登録日	2013-12-12
公開日	2014-12-24
最終更新日	2017-09-06
実験手法	SOLUTION NMR
主引用文献	Structural Basis of p75 Transmembrane Domain Dimerization. J. Biol. Chem., 291, 2016

2N90

TrkA transmembrane domain NMR structure in DPC micelles
分子名称:	High affinity nerve growth factor receptor
著者	Nadezhdin, K, Goncharuk, S, Arseniev, A.
登録日	2015-10-29
公開日	2016-11-09
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor. J.Biol.Chem., 295, 2020

8OYD

TrkB transmembrane domain NMR structure in DMPC/DHPC bicelles
分子名称:	BDNF/NT-3 growth factors receptor
著者	Kot, E.F, Mineev, K.S, Goncharuk, S.A.
登録日	2023-05-04
公開日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Structural Basis for the transmembrane signaling and antidepressant-induced activation of the receptor tyrosine kinase TrkB To Be Published

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表示件数:	24
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