7A3W
 
 | | Structure of Imine Reductase from Pseudomonas sp. | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, NAD(P)-dependent oxidoreductase, ... | | 著者 | Cuetos, A, Thorpe, T, Turner, N.J, Grogan, G. | | 登録日 | 2020-08-18 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Multifunctional biocatalyst for conjugate reduction and reductive amination.
Nature, 604, 2022
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6H7P
 | | Reductive Aminase from Aspergillus terreus in complex with NADPH4, cyclohexanone and allyl amine | | 分子名称: | CYCLOHEXANONE, Reductive Aminase, [[(2~{R},3~{S},4~{R},5~{R})-5-[(3~{R})-3-aminocarbonylpiperidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, ... | | 著者 | Sharma, M, Grogan, G, Mangas-Sanchez, J, Turner, N.J. | | 登録日 | 2018-07-31 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structure of Reductive Aminase from Aspergillus terreus
Acs Catalysis, 2018
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5A9R
 | | Apo form of Imine reductase from Amycolatopsis orientalis | | 分子名称: | ACETATE ION, IMINE REDUCTASE | | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | | 登録日 | 2015-07-22 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis
Acs Catalysis, 6, 2016
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6SLE
 | | Structure of Reductive Aminase from Neosartorya fumigata in complex with NADP+ | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, putative | | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | | 登録日 | 2019-08-19 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.
Chem Sci, 11, 2020
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6SKX
 | | Structure of Reductive Aminase from Neosartorya fumigata | | 分子名称: | Oxidoreductase, putative | | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | | 登録日 | 2019-08-16 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.
Chem Sci, 11, 2020
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2WQ8
 | | Glycan labelling using engineered variants of galactose oxidase obtained by directed evolution | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | | 著者 | Rannes, J.G, Ioannou, A, Willies, S.C, Behrens, C, Grogan, G.J, Flitsch, S.L, Turner, N.J. | | 登録日 | 2009-08-14 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Glycoprotein Labeling Using Engineered Variants of Galactose Oxidase Obtained by Directed Evolution.
J.Am.Chem.Soc., 133, 2011
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5FWN
 | | Imine Reductase from Amycolatopsis orientalis. Closed form in in complex with (R)- Methyltetrahydroisoquinoline | | 分子名称: | (1R)-1-methyl-1,2,3,4-tetrahydroisoquinoline, IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | | 登録日 | 2016-02-18 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis
Acs Catalysis, 6, 2016
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5G2P
 | | The crystal structure of a S-selective transaminase from Arthrobacter sp. | | 分子名称: | CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, TRANSAMINASE | | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | | 登録日 | 2016-04-12 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases
Biochemistry, 55, 2016
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5G6S
 | | Imine reductase from Aspergillus oryzae in complex with NADP(H) and (R)-rasagiline | | 分子名称: | IMINE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RASAGILINE | | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | | 登録日 | 2016-06-23 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A reductive aminase from Aspergillus oryzae.
Nat Chem, 9, 2017
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5G6R
 | | Imine reductase from Aspergillus oryzae | | 分子名称: | IMINE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | | 登録日 | 2016-06-23 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | A reductive aminase from Aspergillus oryzae.
Nat Chem, 9, 2017
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5G2Q
 | | The crystal structure of a S-selective transaminase from Arthrobacter sp. with alanine bound | | 分子名称: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, TRANSAMINASE | | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | | 登録日 | 2016-04-12 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases
Biochemistry, 55, 2016
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5G0A
 | | The crystal structure of a S-selective transaminase from Bacillus megaterium | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | | 登録日 | 2016-03-17 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases
Biochemistry, 55, 2016
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5G09
 | | The crystal structure of a S-selective transaminase from Bacillus megaterium bound with R-alpha-methylbenzylamine | | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | | 著者 | van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. | | 登録日 | 2016-03-17 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases
Biochemistry, 55, 2016
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5A9S
 | | NADPH complex of Imine Reductase from Amycolatopsis orientalis | | 分子名称: | CALCIUM ION, IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | | 登録日 | 2015-07-22 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis
Acs Catalysis, 6, 2016
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5A9T
 | | Imine Reductase from Amycolatopsis orientalis in complex with (R)- Methyltetrahydroisoquinoline | | 分子名称: | (1R)-1-methyl-1,2,3,4-tetrahydroisoquinoline, ACETATE ION, CALCIUM ION, ... | | 著者 | Man, H, Aleku, G, Turner, N.J, Grogan, G. | | 登録日 | 2015-07-22 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Stereoselectivity and Structural Characterization of an Imine Reductase (Ired) from Amycolatopsis Orientalis
Acs Catalysis, 6, 2016
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3ZDN
 | | D11-C mutant of monoamine oxidase from Aspergillus niger | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, MONOAMINE OXIDASE N | | 著者 | Frank, A, Ghislieri, D, Willies, S, Turner, N.J, Grogan, G. | | 登録日 | 2012-11-29 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products.
J.Am.Chem.Soc., 135, 2013
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6EOH
 | | Reductive Aminase from Aspergillus terreus in complex with NADPH and ethyl levulinate | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Reductive Aminase, ethyl levulinate | | 著者 | Sharma, M, Grogan, G, Mangas-Sanchez, J, Turner, N.J. | | 登録日 | 2017-10-09 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases
Acs Catalysis, 2018
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6EOD
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6EOI
 | | Reductive Aminase from Aspergillus terreus in complex with NADPH and ethyl-5-oxohexanoate | | 分子名称: | MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Reductive Aminase, ... | | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | | 登録日 | 2017-10-09 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases
Acs Catalysis, 2018
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5LOC
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7OSN
 | | IRED361 from Micromonospora sp. in complex with NADP+ | | 分子名称: | 6-phosphogluconate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Gilio, A.K, Harawa, V, Turner, N, Grogan, G.J. | | 登録日 | 2021-06-09 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Synthesis of Stereoenriched Piperidines via Chemo-Enzymatic Dearomatization of Activated Pyridines.
J.Am.Chem.Soc., 144, 2022
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5OJL
 | | Imine Reductase from Aspergillus terreus in complex with NADPH4 and dibenz[c,e]azepine | | 分子名称: | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, 5-methyl-7~{H}-benzo[d][2]benzazepine, Imine reductase | | 著者 | Sharma, M, Grogan, G. | | 登録日 | 2017-07-21 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines.
Angew. Chem. Int. Ed. Engl., 56, 2017
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4D3D
 | | Structure of Imine Reductase BcSIRED from Bacillus cereus BAG3X2 | | 分子名称: | IMINE REDUCTASE, MAGNESIUM ION, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL | | 著者 | Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | | 登録日 | 2014-10-21 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.
Chembiochem, 16, 2015
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4D3F
 | | BcSIRED from Bacillus cereus in complex with NADPH | | 分子名称: | IMINE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Man, H, Hart, S, Turkenburg, J.P, Grogan, G. | | 登録日 | 2014-10-21 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structure, Activity and Stereoselectivity of Nadph-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.
Chembiochem, 16, 2015
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2VVM
 | | The structure of MAO-N-D5, a variant of monoamine oxidase from Aspergillus niger. | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, MONOAMINE OXIDASE N, ... | | 著者 | Atkin, K.E, Hart, S, Turkenburg, J.P, Brzozowski, A.M, Grogan, G.J. | | 登録日 | 2008-06-10 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Structure of Monoamine Oxidase from Aspergillus Niger Provides a Molecular Context for Improvements in Activity Obtained by Directed Evolution.
J.Mol.Biol., 384, 2008
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