5OJL

Imine Reductase from Aspergillus terreus in complex with NADPH4 and dibenz[c,e]azepine

Summary for 5OJL

Entry DOI	10.2210/pdb5ojl/pdb
Descriptor	Imine reductase, 5-methyl-7~{H}-benzo[d][2]benzazepine, 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywords	nadph, imine reductase, reductive aminase, oxidoreductase
Biological source	Aspergillus terreus
Total number of polymer chains	1
Total formula weight	31710.79
Authors	Sharma, M.,Grogan, G. (deposition date: 2017-07-21, release date: 2018-05-30, Last modification date: 2024-01-17)
Primary citation	France, S.P.,Aleku, G.A.,Sharma, M.,Mangas-Sanchez, J.,Howard, R.M.,Steflik, J.,Kumar, R.,Adams, R.W.,Slabu, I.,Crook, R.,Grogan, G.,Wallace, T.W.,Turner, N.J. Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines. Angew. Chem. Int. Ed. Engl., 56:15589-15593, 2017 Cited by PubMed: 29024400 DOI: 10.1002/anie.201708453 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation