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5V3F
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BU of 5v3f by Molmil
Co-crystal structure of the fluorogenic RNA Mango
分子名称: 4-{[(2S)-3-{2,16-dioxo-20-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2,3-dihydro-1,3-benzothiazol-2-yl]methyl}-1-methylquinolin-1-ium, PHOSPHATE ION, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2017-03-07
公開日2017-05-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for high-affinity fluorophore binding and activation by RNA Mango.
Nat. Chem. Biol., 13, 2017
6C65
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BU of 6c65 by Molmil
Crystal Structure of the Mango-II-A22U Fluorescent Aptamer Bound to TO1-Biotin
分子名称: 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, POTASSIUM ION, RNA (35-MER), ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-01-17
公開日2018-08-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.80005169 Å)
主引用文献Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness.
Biochemistry, 57, 2018
6C63
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BU of 6c63 by Molmil
Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin
分子名称: 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, POTASSIUM ION, RNA (32-MER), ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-01-17
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.900028 Å)
主引用文献Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness.
Biochemistry, 57, 2018
6C64
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BU of 6c64 by Molmil
Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO3-Biotin
分子名称: 1-methyl-4-[(1E)-3-(3-methyl-1,3-benzothiazol-3-ium-2-yl)prop-1-en-1-yl]quinolin-1-ium, POTASSIUM ION, RNA (32-MER), ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-01-17
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.00014877 Å)
主引用文献Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness.
Biochemistry, 57, 2018
6E8T
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BU of 6e8t by Molmil
Structure of the Mango-III (A10U) aptamer bound to TO1-Biotin
分子名称: 1-methyl-4-{[3-(2-oxopropyl)-1,3-benzothiazol-3-ium-2-yl]methyl}quinolin-1-ium, POTASSIUM ION, RNA (35-MER), ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-07-31
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and functional reselection of the Mango-III fluorogenic RNA aptamer.
Nat. Chem. Biol., 15, 2019
6E8U
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BU of 6e8u by Molmil
Structure of the Mango-III (A10U) aptamer bound to TO1-Biotin
分子名称: 4-[(3-{2,16-dioxo-20-[(3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, MAGNESIUM ION, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-07-31
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure and functional reselection of the Mango-III fluorogenic RNA aptamer.
Nat. Chem. Biol., 15, 2019
6E8S
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BU of 6e8s by Molmil
Structure of the iMango-III aptamer bound to TO1-Biotin
分子名称: 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, MAGNESIUM ION, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2018-07-31
公開日2019-04-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure and functional reselection of the Mango-III fluorogenic RNA aptamer.
Nat. Chem. Biol., 15, 2019
7MLW
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BU of 7mlw by Molmil
Burkholderia sp. TJI49 Guanidine-I riboswitch
分子名称: GUANIDINE, Guanidine-I riboswitch, MAGNESIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2021-04-29
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An uncommon [K + (Mg 2+ ) 2 ] metal ion triad imparts stability and selectivity to the Guanidine-I riboswitch.
Rna, 27, 2021
6UP0
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BU of 6up0 by Molmil
Structure of the Mango-III fluorescent aptamer bound to YO3-Biotin
分子名称: MAGNESIUM ION, Mango-III fluorescent aptamer, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2019-10-16
公開日2020-10-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET.
Rna, 27, 2021
6V9D
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BU of 6v9d by Molmil
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
分子名称: 2-[(E)-(1-methylquinolin-4(1H)-ylidene)methyl]-3-(2-oxopropyl)-1,3-benzothiazol-3-ium, BROMIDE ION, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2019-12-13
公開日2020-05-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair.
Structure, 28, 2020
6V9B
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BU of 6v9b by Molmil
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
分子名称: POTASSIUM ION, RNA (28-MER), ~{N}-methyl-2-[2-[(~{E})-(1-methylquinolin-4-ylidene)methyl]-1,3-benzothiazol-3-yl]ethanamide
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2019-12-13
公開日2020-05-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair.
Structure, 28, 2020
7L0Z
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BU of 7l0z by Molmil
Spinach variant bound to DFHBI-1T
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, PHOSPHATE ION, ...
著者Truong, L, Trachman, R.J, Ferre-D'Amare, A.R.
登録日2020-12-13
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET.
Rna, 27, 2021

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件を2024-07-24に公開中

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