2WLW
 
 | | Structure of the N-terminal capsid domain of HIV-2 | | 分子名称: | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | | 著者 | Price, A.J, Marzetta, F, Lammers, M, Ylinen, L.M.J, Schaller, T, Wilson, S.J, Towers, G.J, James, L.C. | | 登録日 | 2009-06-26 | | 公開日 | 2009-09-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Nat.Struct.Mol.Biol., 16, 2009
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2WLV
 | | Structure of the N-terminal capsid domain of HIV-2 | | 分子名称: | GAG POLYPROTEIN | | 著者 | Price, A.J, Marzetta, F, Lammers, M, Ylinen, L.M.J, Schaller, T, Wilson, S.J, Towers, G.J, James, L.C. | | 登録日 | 2009-06-26 | | 公開日 | 2009-09-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Nat.Struct.Mol.Biol., 16, 2009
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4IPZ
 | | SmBz bound to Cyclophilin A | | 分子名称: | CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase A, cyclosporine SmBz-CsA | | 著者 | Price, A.J, Jacques, D.A, James, L.C. | | 登録日 | 2013-01-10 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | HIV-1 evades innate immune recognition through specific cofactor recruitment.
Nature, 503, 2013
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5JPA
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5A0E
 | | Crystal structure of cyclophilin D in complex with CsA analogue, JW47. | | 分子名称: | JW47, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL | | 著者 | Warne, J, Pryce, G, Hill, J, Shi, X, Lenneras, F, Puentes, F, Kip, M, Hilditch, L, Walker, P, Simone, M, Chan, A.W.E, Towers, G, Coker, A.R, Duchen, M, Szabadkai, G, Baker, D, Selwood, D.L. | | 登録日 | 2015-04-19 | | 公開日 | 2015-12-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects Against Neuro-Degeneration in Experimental Multiple Sclerosis.
J.Biol.Chem., 291, 2016
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7QDF
 | | Hexameric HIV-1 (M-group) CA R120 mutant | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Gag polyprotein, ... | | 著者 | Govasli, M.A.L, Pinotsis, N, McAlpine-Scott, S. | | 登録日 | 2021-11-26 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
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4LQW
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7T13
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7T12
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7T15
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7T14
 | | Hexameric SIVmac CA | | 分子名称: | Capsid protein p24 | | 著者 | Jacques, D.A, James, L.C. | | 登録日 | 2021-12-01 | | 公開日 | 2022-10-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
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8D3B
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6ES8
 | | HIV capsid hexamer with IP6 ligand | | 分子名称: | Gag protein, INOSITOL HEXAKISPHOSPHATE | | 著者 | James, L.C. | | 登録日 | 2017-10-19 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.
Elife, 7, 2018
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5HGP
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4DGE
 | | TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant, HIV-1 CA(O-loop) complex | | 分子名称: | TRIMCyp, capsid protein | | 著者 | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | | 登録日 | 2012-01-25 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
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4DGA
 | | TRIMCyp cyclophilin domain from Macaca mulatta: HIV-1 CA(O-loop) complex | | 分子名称: | TRIMCyp, capsid protein | | 著者 | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | | 登録日 | 2012-01-25 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
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4DGD
 | | TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant | | 分子名称: | GLYCEROL, TRIMCyp | | 著者 | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | | 登録日 | 2012-01-25 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
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4DGB
 | | TRIMCyp cyclophilin domain from Macaca mulatta: HIV-2 CA cyclophilin-binding loop complex | | 分子名称: | TRIMCyp, capsid protein | | 著者 | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | | 登録日 | 2012-01-25 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
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5HGN
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5HGL
 | | Hexameric HIV-1 CA, open conformation | | 分子名称: | CHLORIDE ION, Capsid protein P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE | | 著者 | Price, A.J, Jacques, D.A, James, L.C. | | 登録日 | 2016-01-08 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
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5HGM
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5HGK
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4DGC
 | | TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex | | 分子名称: | TRIMCyp, cyclosporin A | | 著者 | Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. | | 登録日 | 2012-01-25 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
Nat.Struct.Mol.Biol., 19, 2012
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5HGO
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4B4N
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