5HGM

Hexameric HIV-1 CA in complex with dATP

Summary for 5HGM

Entry DOI	10.2210/pdb5hgm/pdb
Descriptor	Capsid protein P24, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	capsid, viral protein
Biological source	Human immunodeficiency virus 1 (HIV-1)
Cellular location	Gag polyprotein: Host cell membrane; Lipid- anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493
Total number of polymer chains	1
Total formula weight	25952.45
Authors	Jacques, D.A.,James, L.C. (deposition date: 2016-01-08, release date: 2016-08-10, Last modification date: 2024-01-10)
Primary citation	Jacques, D.A.,McEwan, W.A.,Hilditch, L.,Price, A.J.,Towers, G.J.,James, L.C. HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536:349-353, 2016 Cited by PubMed: 27509857 DOI: 10.1038/nature19098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation