1VTD
| UNUSUAL HELICAL PACKING IN CRYSTALS OF DNA BEARING A MUTATION HOT SPOT | 分子名称: | DNA (5'-D(*AP*CP*CP*GP*GP*CP*GP*CP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*GP*CP*GP*CP*CP*GP*GP*T)-3') | 著者 | Timsit, Y, Westhof, E, Fuchs, R.P.P, Moras, D. | 登録日 | 1996-12-12 | 公開日 | 2011-07-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Unusual helical packing in crystals of DNA bearing a mutation hot spot. Nature, 341, 1989
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1QC1
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1QP5
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2GHJ
| Crystal structure of folded and partially unfolded forms of Aquifex aeolicus ribosomal protein L20 | 分子名称: | 50S ribosomal protein L20, SULFATE ION | 著者 | Timsit, Y, Allemand, F, Chiaruttini, C, Springer, M. | 登録日 | 2006-03-27 | 公開日 | 2006-04-18 | 最終更新日 | 2018-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Coexistence of two protein folding states in the crystal structure of ribosomal protein L20 Embo Rep., 7, 2006
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330D
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2R22
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2R20
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2R21
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2R1S
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329D
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382D
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383D
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384D
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8D73
| Crystal Structure of EGFR LRTM with compound 7 | 分子名称: | (3S,4R)-3-fluoro-1-(4-{[4-(methylamino)-1-(propan-2-yl)pyrido[3,4-d]pyridazin-7-yl]amino}pyrimidin-2-yl)piperidin-4-ol, Epidermal growth factor receptor, GLYCEROL | 著者 | Kim, J.L. | 登録日 | 2022-06-07 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer. J.Med.Chem., 65, 2022
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8D76
| Crystal Structure of EGFR LRTM with compound 24 | 分子名称: | (3S,4R)-3-fluoro-1-(4-{[8-{3-[(methanesulfonyl)methyl]azetidin-1-yl}-5-(propan-2-yl)-2,7-naphthyridin-3-yl]amino}pyrimidin-2-yl)-3-methylpiperidin-4-ol, Epidermal growth factor receptor, GLYCEROL | 著者 | Kim, J.L. | 登録日 | 2022-06-07 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer. J.Med.Chem., 65, 2022
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