1SNU
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![BU of 1snu by Molmil](/molmil-images/mine/1snu) | CRYSTAL STRUCTURE OF THE UNPHOSPHORYLATED INTERLEUKIN-2 TYROSINE KINASE CATALYTIC DOMAIN | 分子名称: | STAUROSPORINE, Tyrosine-protein kinase ITK/TSK | 著者 | Brown, K, Long, J.M, Vial, S.C, Dedi, N, Dunster, N.J, Renwick, S.B, Tanner, A.J, Frantz, J.D, Fleming, M.A, Cheetham, G.M.T. | 登録日 | 2004-03-12 | 公開日 | 2004-07-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors. J.Biol.Chem., 279, 2004
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1SM2
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![BU of 1sm2 by Molmil](/molmil-images/mine/1sm2) | Crystal structure of the phosphorylated Interleukin-2 tyrosine kinase catalytic domain | 分子名称: | STAUROSPORINE, Tyrosine-protein kinase ITK/TSK | 著者 | Brown, K, Long, J.M, Vial, S.C.M, Dedi, N, Dunster, N.J, Renwick, S.B, Tanner, A.J, Frantz, J.D, Fleming, M.A, Cheetham, G.M.T. | 登録日 | 2004-03-08 | 公開日 | 2004-07-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors. J.Biol.Chem., 279, 2004
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1SNX
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![BU of 1snx by Molmil](/molmil-images/mine/1snx) | CRYSTAL STRUCTURE OF APO INTERLEUKIN-2 TYROSINE KINASE CATALYTIC DOMAIN | 分子名称: | Tyrosine-protein kinase ITK/TSK | 著者 | Brown, K, Long, J.M, Vial, S.C, Dedi, N, Dunster, N.J, Renwick, S.B, Tanner, A.J, Frantz, J.D, Fleming, M.A, Cheetham, G.M.T. | 登録日 | 2004-03-12 | 公開日 | 2004-07-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structures of interleukin-2 tyrosine kinase and their implications for the design of selective inhibitors. J.Biol.Chem., 279, 2004
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3QGW
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![BU of 3qgw by Molmil](/molmil-images/mine/3qgw) | Crystal Structure of ITK kinase bound to an inhibitor | 分子名称: | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide, N-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)benzamide, Tyrosine-protein kinase ITK/TSK | 著者 | Brown, K, Cheetham, G.M.T. | 登録日 | 2011-01-25 | 公開日 | 2011-06-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors J.Med.Chem., 54, 2011
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3QGY
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![BU of 3qgy by Molmil](/molmil-images/mine/3qgy) | Crystal structure of ITK inhibitor complex | 分子名称: | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide, N-{5-[2-(methylamino)pyrimidin-4-yl]-2-oxo-1,2-dihydropyridin-3-yl}-4-(piperidin-1-yl)benzamide, Tyrosine-protein kinase ITK/TSK | 著者 | Brown, K, Cheetham, G.M.T. | 登録日 | 2011-01-25 | 公開日 | 2011-06-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors J.Med.Chem., 54, 2011
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