1CI5
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![BU of 1ci5 by Molmil](/molmil-images/mine/1ci5) | GLYCAN-FREE MUTANT ADHESION DOMAIN OF HUMAN CD58 (LFA-3) | 分子名称: | PROTEIN (LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 3(CD58)) | 著者 | Sun, Z.Y.J, Dotsch, V, Kim, M, Li, J, Reinherz, E.L, Wagner, G. | 登録日 | 1999-04-07 | 公開日 | 1999-06-22 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Functional glycan-free adhesion domain of human cell surface receptor CD58: design, production and NMR studies. EMBO J., 18, 1999
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6UCH
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![BU of 6uch by Molmil](/molmil-images/mine/6uch) | SMARCB1 nucleosome-interacting C-terminal alpha helix | 分子名称: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | 著者 | Valencia, A.M, Sun, Z.Y.J, Seo, H.S, Vangos, H.S, Yeoh, Z.C, Mashtalir, N, Dhe-Paganon, S, Kadoch, C. | 登録日 | 2019-09-16 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell, 179, 2019
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1Q68
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![BU of 1q68 by Molmil](/molmil-images/mine/1q68) | Solution structure of T-cell surface glycoprotein CD4 and Proto-oncogene tyrosine-protein kinase LCK fragments | 分子名称: | Proto-oncogene tyrosine-protein kinase LCK, T-cell surface glycoprotein CD4, ZINC ION | 著者 | Kim, P.W, Sun, Z.Y, Blacklow, S.C, Wagner, G, Eck, M.J. | 登録日 | 2003-08-12 | 公開日 | 2003-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science, 301, 2003
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1Q69
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![BU of 1q69 by Molmil](/molmil-images/mine/1q69) | Solution structure of T-cell surface glycoprotein CD8 alpha chain and Proto-oncogene tyrosine-protein kinase LCK fragments | 分子名称: | Proto-oncogene tyrosine-protein kinase LCK, T-cell surface glycoprotein CD8 alpha chain, ZINC ION | 著者 | Kim, P.W, Sun, Z.Y, Blacklow, S.C, Wagner, G, Eck, M.J. | 登録日 | 2003-08-12 | 公開日 | 2003-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science, 301, 2003
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7XQT
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![BU of 7xqt by Molmil](/molmil-images/mine/7xqt) | The structure of FLA-K*00701/KP-FECV-11 | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | 登録日 | 2022-05-08 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
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7XQS
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![BU of 7xqs by Molmil](/molmil-images/mine/7xqs) | The structure of FLA-K*00701/KP-CoV-9 | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | 登録日 | 2022-05-08 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
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7XQU
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![BU of 7xqu by Molmil](/molmil-images/mine/7xqu) | The structure of FLA-E*00301/EM-FECV-10 | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide from Nucleoprotein | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | 登録日 | 2022-05-08 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
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2JOG
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![BU of 2jog by Molmil](/molmil-images/mine/2jog) | Structure of the calcineurin-NFAT complex | 分子名称: | Calmodulin-dependent calcineurin A subunit alpha isoform, NFAT | 著者 | Takeuchi, K, Roehrl, M.H, Sun, Z.Y, Wagner, G. | 登録日 | 2007-03-10 | 公開日 | 2007-05-22 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal Coordinates. Structure, 15, 2007
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1XMW
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![BU of 1xmw by Molmil](/molmil-images/mine/1xmw) | CD3 EPSILON AND DELTA ECTODOMAIN FRAGMENT COMPLEX IN SINGLE-CHAIN CONSTRUCT | 分子名称: | Chimeric CD3 mouse Epsilon and sheep Delta Ectodomain Fragment Complex | 著者 | Sun, Z.-Y.J, Kim, S.T, Kim, I.C, Fahmy, A, Reinherz, E.L, Wagner, G. | 登録日 | 2004-10-04 | 公開日 | 2004-11-30 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling. Proc.Natl.Acad.Sci.Usa, 101, 2004
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2ME4
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![BU of 2me4 by Molmil](/molmil-images/mine/2me4) | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME1
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![BU of 2me1 by Molmil](/molmil-images/mine/2me1) | HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Gp41 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2ME3
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![BU of 2me3 by Molmil](/molmil-images/mine/2me3) | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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2PV6
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![BU of 2pv6 by Molmil](/molmil-images/mine/2pv6) | HIV-1 gp41 Membrane Proximal Ectodomain Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein | 著者 | Sun, Z.-Y.J, Oh, K.J, Kim, M, Reinherz, E.L, Wagner, G. | 登録日 | 2007-05-09 | 公開日 | 2008-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane Immunity, 28, 2008
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2ME2
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![BU of 2me2 by Molmil](/molmil-images/mine/2me2) | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | 分子名称: | Envelope glycoprotein gp160 | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | 登録日 | 2013-09-20 | 公開日 | 2013-10-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
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1QA9
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![BU of 1qa9 by Molmil](/molmil-images/mine/1qa9) | Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors | 分子名称: | HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN | 著者 | Wang, J.-H, Smolyar, A, Tan, K, Liu, J.-H, Kim, M, Sun, Z.J, Wagner, G, Reinherz, E.L. | 登録日 | 1999-04-13 | 公開日 | 1999-04-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell(Cambridge,Mass.), 97, 1999
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3L59
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![BU of 3l59 by Molmil](/molmil-images/mine/3l59) | Structure of BACE Bound to SCH710413 | 分子名称: | (2Z)-3-(3-chlorobenzyl)-2-imino-5,5-dimethylimidazolidin-4-one, Beta-secretase 1, D(-)-TARTARIC ACID | 著者 | Strickland, C, Zhu, Z. | 登録日 | 2009-12-21 | 公開日 | 2010-02-16 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation J.Med.Chem., 53, 2010
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3L58
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![BU of 3l58 by Molmil](/molmil-images/mine/3l58) | Structure of BACE Bound to SCH589432 | 分子名称: | Beta-secretase 1, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | 著者 | Strickland, C, Zhu, Z. | 登録日 | 2009-12-21 | 公開日 | 2010-02-16 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation J.Med.Chem., 53, 2010
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3L5B
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![BU of 3l5b by Molmil](/molmil-images/mine/3l5b) | Structure of BACE Bound to SCH713601 | 分子名称: | (2Z,5R)-3-(3-chlorobenzyl)-2-imino-5-methyl-5-(2-methylpropyl)imidazolidin-4-one, Beta-secretase 1, D(-)-TARTARIC ACID | 著者 | Strickland, C, Zhu, Z. | 登録日 | 2009-12-21 | 公開日 | 2010-02-16 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation J.Med.Chem., 53, 2010
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3L5E
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![BU of 3l5e by Molmil](/molmil-images/mine/3l5e) | Structure of BACE Bound to SCH736062 | 分子名称: | (4S)-1-(4-{[(2Z,4R)-4-(2-cyclohexylethyl)-4-(cyclohexylmethyl)-2-imino-5-oxoimidazolidin-1-yl]methyl}benzyl)-4-propylimidazolidin-2-one, Beta-secretase 1, D(-)-TARTARIC ACID | 著者 | Strickland, C, Zhu, Z. | 登録日 | 2009-12-21 | 公開日 | 2010-02-16 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation J.Med.Chem., 53, 2010
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1P4Q
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![BU of 1p4q by Molmil](/molmil-images/mine/1p4q) | Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain | 分子名称: | Cbp/p300-interacting transactivator 2, E1A-associated protein p300, ZINC ION | 著者 | Freedman, S.J, Sun, Z.-Y.J, Kung, A.L, France, D.S, Wagner, G, Eck, M.J. | 登録日 | 2003-04-23 | 公開日 | 2003-07-01 | 最終更新日 | 2017-02-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2. Nat.Struct.Biol., 10, 2003
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1L3E
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![BU of 1l3e by Molmil](/molmil-images/mine/1l3e) | NMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex | 分子名称: | ZINC ION, hypoxia inducible factor-1 alpha subunit, p300 protein | 著者 | Freedman, S.J, Sun, Z.J, Poy, F, Kung, A.L, Livingston, D.M, Wagner, G, Eck, M.J. | 登録日 | 2002-02-26 | 公開日 | 2002-04-24 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha. Proc.Natl.Acad.Sci.USA, 99, 2002
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1NHL
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1JBJ
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![BU of 1jbj by Molmil](/molmil-images/mine/1jbj) | CD3 Epsilon and gamma Ectodomain Fragment Complex in Single-Chain Construct | 分子名称: | CD3 Epsilon and gamma Ectodomain Fragment Complex | 著者 | Sun, Z.-Y.J, Kim, K.S, Wagner, G, Reinherz, E.L. | 登録日 | 2001-06-05 | 公開日 | 2001-12-05 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Mechanisms contributing to T cell receptor signaling and assembly revealed by the solution structure of an ectodomain fragment of the CD3 epsilon gamma heterodimer. Cell(Cambridge,Mass.), 105, 2001
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8XKE
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![BU of 8xke by Molmil](/molmil-images/mine/8xke) | The structure of HLA-A/14-3-D | 分子名称: | Beta-2-microglobulin, GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR, HLA class I heavy chain | 著者 | Zhang, J.N, Yue, C, Liu, J, Sun, Z.Y. | 登録日 | 2023-12-23 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals. Immunohorizons, 8, 2024
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2JXB
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![BU of 2jxb by Molmil](/molmil-images/mine/2jxb) | Structure of CD3epsilon-Nck2 first SH3 domain complex | 分子名称: | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 | 著者 | Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G. | 登録日 | 2007-11-09 | 公開日 | 2008-09-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity. J.Mol.Biol., 380, 2008
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