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6BS9
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BU of 6bs9 by Molmil
Stage III sporulation protein AB (SpoIIIAB)
分子名称: SULFATE ION, Stage III sporulation protein AB
著者Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A.
登録日2017-12-01
公開日2018-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis.
J. Struct. Biol., 202, 2018
6DCS
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BU of 6dcs by Molmil
Stage III sporulation protein AF (SpoIIIAF)
分子名称: SULFATE ION, Stage III sporulation protein AF
著者Strynadka, N.C.J, Zeytuni, N, Camp, A.H, Flanagan, K.A.
登録日2018-05-08
公開日2018-07-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis.
J. Struct. Biol., 204, 2018
6PEE
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BU of 6pee by Molmil
InvG secretin domain beta-barrel from Salmonella SPI-1 injectisome NC-base
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Protein InvG
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-06-20
公開日2019-10-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6ZTG
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BU of 6ztg by Molmil
Spor protein DedD
分子名称: Cell division protein DedD
著者Pazos, M, Peters, K, Boes, A, Safaei, Y, Kenward, C, Caveney, N.A, Laguri, C, Breukink, E, Strynadka, N.C.J, Simorre, J.P, Terrak, M, Vollmer, W.
登録日2020-07-20
公開日2020-11-11
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli.
Mbio, 11, 2020
5TXI
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BU of 5txi by Molmil
Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole
分子名称: (2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyr rolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
著者Alexander, J.A.N, Strynadka, N.C.J.
登録日2016-11-16
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 2018
1KN9
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BU of 1kn9 by Molmil
CRYSTAL STRUCTURE OF A BACTERIAL SIGNAL PEPTIDASE APO-ENZYME, IMPLICATIONS FOR SIGNAL PEPTIDE BINDING AND THE SER-LYS DYAD MECHANISM.
分子名称: Signal peptidase I
著者Paetzel, M, Dalbey, R.E, Strynadka, N.C.J.
登録日2001-12-18
公開日2002-01-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
J.Biol.Chem., 277, 2002
7UZ2
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BU of 7uz2 by Molmil
Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-fluoro-valienide.
分子名称: (1R,2S,3R,4R)-5-fluoro-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, Beta-galactosidase
著者Danby, P.M, Jeong, A, Sim, L, Sweeney, R.P, Wardman, J.F, Geissner, A, Worrall, L.J, Strynadka, N.C.J, Withers, S.G.
登録日2022-05-08
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors.
Angew.Chem.Int.Ed.Engl., 62, 2023
7UZ1
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BU of 7uz1 by Molmil
Structure of beta-glycosidase from Sulfolobus solfataricus in complex with C5a-bromo-valienide.
分子名称: (1R,2S,3R,4R)-5-bromo-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, 1,2-ETHANEDIOL, Beta-galactosidase
著者Danby, P.M, Jeong, A, Sim, L, Sweeney, R.P, Wardman, J.F, Karimi, R, Geissner, A, Worrall, L.J, Strynadka, N.C.J, Withers, S.G.
登録日2022-05-08
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Vinyl Halide-Modified Unsaturated Cyclitols are Mechanism-Based Glycosidase Inhibitors.
Angew.Chem.Int.Ed.Engl., 62, 2023
7TC5
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BU of 7tc5 by Molmil
All Phe-Azurin variant - F15Y
分子名称: Azurin, COPPER (II) ION, NITRATE ION, ...
著者Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
登録日2021-12-22
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
7TC6
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BU of 7tc6 by Molmil
All Phe-Azurin variant - F15W
分子名称: Azurin, COPPER (II) ION, NITRATE ION
著者Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
登録日2021-12-22
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
2DRJ
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BU of 2drj by Molmil
Xray structure of alpha-2,3/8-sialyltransferase CstII F91Y mutant
分子名称: Alpha-2,3/8-sialyltransferase, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, ISOPROPYL ALCOHOL
著者Chiu, C.P.C, Strynadka, N.C.J.
登録日2006-06-09
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献High-throughput screening methodology for the directed evolution of glycosyltransferases
Nat.Methods, 3, 2006
2F2H
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BU of 2f2h by Molmil
Structure of the YicI thiosugar Michaelis complex
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-NITROPHENYL 6-THIO-6-S-ALPHA-D-XYLOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, GLYCEROL, ...
著者Kim, Y.-W, Lovering, A.L, Strynadka, N.C.J, Withers, S.G.
登録日2005-11-16
公開日2006-02-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Expanding the Thioglycoligase Strategy to the Synthesis of alpha-linked Thioglycosides Allows Structural Investigation of the Parent Enzyme/Substrate Complex
J.Am.Chem.Soc., 128, 2006
7LBU
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BU of 7lbu by Molmil
Crystal structure of the Propionibacterium acnes surface sialidase
分子名称: ACETATE ION, Exo-alpha-sialidase, PHOSPHATE ION
著者Yu, A.C.Y, Volkers, G, Strynadka, N.C.J.
登録日2021-01-08
公開日2021-12-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases.
Glycobiology, 32, 2022
7LBV
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BU of 7lbv by Molmil
Crystal structure of the Propionibacterium acnes surface sialidase in complex with Neu5Ac2en
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Exo-alpha-sialidase, PHOSPHATE ION
著者Yu, A.C.Y, Volkers, G, Strynadka, N.C.J.
登録日2021-01-09
公開日2021-12-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases.
Glycobiology, 32, 2022
7LQ6
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BU of 7lq6 by Molmil
CryoEM structure of Escherichia coli PBP1b
分子名称: Penicillin-binding protein 1B
著者Caveney, N.A, Workman, S.D, Yan, R, Atkinson, C.E, Yu, Z, Strynadka, N.C.J.
登録日2021-02-13
公開日2021-05-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献CryoEM structure of the antibacterial target PBP1b at 3.3 angstrom resolution.
Nat Commun, 12, 2021
6C39
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BU of 6c39 by Molmil
Apo crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4)
分子名称: SODIUM ION, SULFATE ION, Serine-type D-Ala-D-Ala carboxypeptidase, ...
著者Alexander, J.A.N, Strynadka, N.C.J.
登録日2018-01-09
公開日2018-11-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 293, 2018
6C3K
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BU of 6c3k by Molmil
Apo crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R)
分子名称: CHLORIDE ION, Penicillin-binding protein 4, SODIUM ION, ...
著者Alexander, J.A.N, Strynadka, N.C.J.
登録日2018-01-10
公開日2018-11-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.
J. Biol. Chem., 293, 2018
1Y5I
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BU of 1y5i by Molmil
The crystal structure of the NarGHI mutant NarI-K86A
分子名称: (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, FE3-S4 CLUSTER, ...
著者Bertero, M.G, Rothery, R.A, Boroumand, N, Palak, M, Blasco, F, Ginet, N, Weiner, J.H, Strynadka, N.C.J.
登録日2004-12-02
公開日2005-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Biochemical Characterization of a Quinol Binding Site of Escherichia coli Nitrate Reductase A
J.Biol.Chem., 280, 2005
6PEM
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BU of 6pem by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-06-20
公開日2019-10-23
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q15
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BU of 6q15 by Molmil
Structure of the Salmonella SPI-1 injectisome needle complex
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-08-02
公開日2019-10-23
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (5.15 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q14
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BU of 6q14 by Molmil
Structure of the Salmonella SPI-1 injectisome NC-base
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-08-02
公開日2019-10-23
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q16
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BU of 6q16 by Molmil
Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-08-02
公開日2019-10-23
最終更新日2020-01-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
5WD7
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BU of 5wd7 by Molmil
Structure of a bacterial polysialyltransferase in complex with fondaparinux
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, SULFATE ION, SiaD
著者Worrall, L.J, Lizak, C, Strynadka, N.C.J.
登録日2017-07-04
公開日2017-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.
Sci Rep, 7, 2017
6UEX
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BU of 6uex by Molmil
Crystal structure of S. aureus LcpA in complex with octaprenyl-pyrophosphate-GlcNAc
分子名称: 2-(acetylamino)-2-deoxy-1-O-[(S)-hydroxy{[(S)-hydroxy{[(2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl]oxy}phosphoryl]oxy}phosphoryl]-alpha-D-glucopyranose, GLYCEROL, Regulatory protein MsrR, ...
著者Li, F.K.K, Strynadka, N.C.J.
登録日2019-09-23
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020
6UF6
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BU of 6uf6 by Molmil
Crystal structure of B. subtilis TagU
分子名称: GLYCEROL, Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU, SULFATE ION
著者Li, F.K.K, Strynadka, N.C.J.
登録日2019-09-23
公開日2020-01-29
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic analysis ofStaphylococcus aureusLcpA, the primary wall teichoic acid ligase.
J.Biol.Chem., 295, 2020

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