7P7D
 
 | | Rabbit muscle Glycogen Phosphorylase T state | | 分子名称: | DIMETHYL SULFOXIDE, Glycogen phosphorylase, muscle form | | 著者 | Stravodimos, G.A, Leonidas, D.D. | | 登録日 | 2021-07-19 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators.
Acta Crystallogr.,Sect.F, 77, 2021
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8BZS
 | | The crystal structure of glycogen phosphorylase in complex with baicalein | | 分子名称: | 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Glycogen phosphorylase, muscle form, ... | | 著者 | Koulas, S.M, Mathomes, R, Hayes, J.M, Leonidas, D.D. | | 登録日 | 2022-12-15 | | 公開日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its' potential against glioblastoma in cellular models.
Chem.Biol.Interact., 382, 2023
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8PPN
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8OJM
 | | Galectin-3 in complex with 2,6-anhydro-3-deoxy-3-S-(beta-D-galactopyranosyl)-3-thio-D-glycero-D-galacto-heptonamide | | 分子名称: | (2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxane-2-carboxamide, 1-thio-beta-D-galactopyranose, Galectin-3, ... | | 著者 | Tsagkarakou, A.S, Leonidas, D.D. | | 登録日 | 2023-03-24 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Strong Binding of C -Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds.
J.Med.Chem., 66, 2023
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8OJI
 | | Galectin-3 in complex with Methyl 2,6-anhydro-3-deoxy-3-S-(b-D-galactopyranosyl)-3-thio-D-glycero-L-altro-heptonate | | 分子名称: | 1-thio-beta-D-galactopyranose, CHLORIDE ION, Galectin-3, ... | | 著者 | Tsagkarakou, A.S, Leonidas, D.D. | | 登録日 | 2023-03-24 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Strong Binding of C -Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds.
J.Med.Chem., 66, 2023
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8OJK
 | | Galectin-3 in complex with 2,6-anhydro-3-deoxy-3-S-(beta-D-galactopyranosyl)-3-thio-D-glycero-L-altro-heptonamide | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxane-2-carboxamide, 1-thio-beta-D-galactopyranose, Galectin-3, ... | | 著者 | Tsagkarakou, A.S, Leonidas, D.D. | | 登録日 | 2023-03-24 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Strong Binding of C -Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds.
J.Med.Chem., 66, 2023
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8OJO
 | | Galectin-3 in complex with 2,6-Anhydro-5-S-(beta-D-galactopyranosyl)-5-thio-D-altritol | | 分子名称: | 1-deoxy-alpha-D-mannopyranose, 1-thio-beta-D-galactopyranose, Galectin-3, ... | | 著者 | Tsagkarakou, A.S, Leonidas, D.D. | | 登録日 | 2023-03-24 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Strong Binding of C -Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds.
J.Med.Chem., 66, 2023
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3E3L
 | | The R-state Glycogen Phosphorylase | | 分子名称: | Glycogen phosphorylase, muscle form, SULFATE ION | | 著者 | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-08-07 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators.
Acta Crystallogr.,Sect.F, 77, 2021
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3E3N
 | | The Glycogen phosphorylase b R state- AMP complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, Glycogen phosphorylase, muscle form, ... | | 著者 | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-08-07 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators.
Acta Crystallogr.,Sect.F, 77, 2021
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3E3O
 | | Glycogen phosphorylase R state-IMP complex | | 分子名称: | Glycogen phosphorylase, muscle form, INOSINIC ACID, ... | | 著者 | Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | | 登録日 | 2008-08-07 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Glycogen phosphorylase revisited: extending the resolution of the R- and T-state structures of the free enzyme and in complex with allosteric activators.
Acta Crystallogr.,Sect.F, 77, 2021
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8QCW
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5OWY
 | | Glycogen Phosphorylase in complex with KS252 | | 分子名称: | 4-[5-[(2~{S},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-4~{H}-1,2,4-triazol-3-yl]benzoic acid, Glycogen phosphorylase, muscle form, ... | | 著者 | Kyriakis, E, Stravodimos, G, Kantsadi, A, Chatzileontiadou, D, Leonidas, D. | | 登録日 | 2017-09-05 | | 公開日 | 2018-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors.
Bioorg. Chem., 77, 2018
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