8USO
 
 | | Full-length human CaMKII delta holoenzyme | | 分子名称: | MALONATE ION, calcium/calmodulin-dependent protein kinase | | 著者 | Ozden, C, Abromson, N.L, Tomchick, D.R, Stratton, M.M, Garman, S.C. | | 登録日 | 2023-10-28 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Full-length human CaMKII delta holoenzyme
To be published
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6X5G
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and LRRC7 inhibitory domain | | 分子名称: | BICINE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, ... | | 著者 | Ozden, C, Stratton, M.M, Garman, S.C. | | 登録日 | 2020-05-26 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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6W4P
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6W4O
 | | CaMKII alpha-30 Cryo-EM reconstruction | | 分子名称: | Calcium/calmodulin-dependent protein kinase type II subunit alpha | | 著者 | Chao, L.H, Stratton, M.M. | | 登録日 | 2020-03-11 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation.
Sci.Signal., 13, 2020
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6VZK
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6X5Q
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7UIR
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and Tiam1 in complex with ATP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | | 著者 | Ozden, C, Stratton, M.M, Garman, S.C. | | 登録日 | 2022-03-29 | | 公開日 | 2022-04-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7UIQ
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7UIS
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7UJS
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... | | 著者 | Ozden, C, Santos, N.J, Stratton, M.M, Garman, S.C. | | 登録日 | 2022-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7UJT
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, ... | | 著者 | Ozden, C, Stratton, M.M, Garman, S.C. | | 登録日 | 2022-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7UJR
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | | 分子名称: | 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... | | 著者 | Ozden, C, Santos, N.J, Stratton, M.M, Garman, S.C. | | 登録日 | 2022-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7UJQ
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | | 分子名称: | Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, Glutamate receptor ionotropic, ... | | 著者 | Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C. | | 登録日 | 2022-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7UJP
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | | 著者 | Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C. | | 登録日 | 2022-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7URY
 | | Tetradecameric hub domain of CaMKII beta | | 分子名称: | Calcium/calmodulin-dependent protein kinase type II subunit beta, D-MALATE | | 著者 | Ozden, C, Saha, S, Samkutty, A, Stratton, M.M, Garman, S.C, Perry, S.L. | | 登録日 | 2022-04-22 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Polymer-based microfluidic device for on-chip counter-diffusive crystallization and in situ X-ray crystallography at room temperature.
Lab Chip, 23, 2023
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7URW
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7URZ
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7KL2
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7KL1
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | | 著者 | Ozden, C, Stratton, M.M, Garman, S.C. | | 登録日 | 2020-10-28 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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7KL0
 | | Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) | | 分子名称: | 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... | | 著者 | Ozden, C, Stratton, M.M, Garman, S.C. | | 登録日 | 2020-10-28 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
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9EOY
 | | Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CaMKII alpha hub bound to PIPA | | 分子名称: | 2-[6-(4-chlorophenyl)imidazo[1,2-b]pyridazin-2-yl]ethanoic acid, ACETATE ION, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... | | 著者 | Narayanan, D, Larsen, A.S.G, Solbak, S.M.O, Wellendorph, P, Gee, C.L, Kastrup, J.S. | | 登録日 | 2024-03-15 | | 公開日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Ligand-induced CaMKII alpha hub Trp403 flip, hub domain stacking, and modulation of kinase activity.
Protein Sci., 33, 2024
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6YTU
 | | Atomic-resolution structure of the coiled-coil dimerisation domain of human Arc | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Activity-regulated cytoskeleton-associated protein, CHLORIDE ION | | 著者 | Hallin, E.I, Touma, C, Bramham, C.R, Kursula, P. | | 登録日 | 2020-04-24 | | 公開日 | 2021-03-03 | | 最終更新日 | 2021-05-12 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif.
Febs J., 288, 2021
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5IG4
 | | Crystal structure of N. vectensis CaMKII-A hub | | 分子名称: | GLYCEROL, Predicted protein | | 著者 | Bhattacharyya, M, Pappireddi, N, Gee, C.L, Barros, T, Kuriyan, J. | | 登録日 | 2016-02-26 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.
Elife, 5, 2016
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5IG1
 | | Crystal structure of S. rosetta CaMKII kinase domain | | 分子名称: | CAMK/CAMK2 protein kinase, PHOSPHATE ION | | 著者 | Bhattacharyya, M, Gee, C.L, Barros, T, Kuriyan, J. | | 登録日 | 2016-02-26 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.
Elife, 5, 2016
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5IG3
 | | Crystal structure of the human CaMKII-alpha hub | | 分子名称: | Calcium/calmodulin-dependent protein kinase type II subunit alpha | | 著者 | McSpadden, E, Cao, Y.M, Bhattacharyya, M, Gee, C.L, Barros, T, Kuriyan, J. | | 登録日 | 2016-02-26 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.
Elife, 5, 2016
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