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4AJX
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BU of 4ajx by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: IMIDAZOLE, INSULIN, N-(16-Carboxyhexadecanoyl)-L-glutamic acid, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-20
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AJZ
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BU of 4ajz by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AKJ
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BU of 4akj by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-23
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4AK0
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BU of 4ak0 by Molmil
Ligand controlled assembly of hexamers, dihexamers, and linear multihexamer structures by an engineered acylated insulin
分子名称: INSULIN A CHAIN, INSULIN B CHAIN
著者Steensgaard, D.B, Schluckebier, G, Strauss, H.M, Norrman, M, Thomsen, J.K, Friderichsen, A.V, Havelund, S, Jonassen, I.
登録日2012-02-21
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures by the Engineered Acylated Insulin Degludec.
Biochemistry, 52, 2013
4APD
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BU of 4apd by Molmil
Liraglutide
分子名称: LIRAGLUTIDE, N-hexadecanoyl-L-glutamic acid
著者Ludvigsen, S, Steensgaard, D.B, Thomsen, J.K, Strauss, H, Normann, M.
登録日2012-04-02
公開日2013-07-10
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Liraglutide
To be Published
4EFX
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BU of 4efx by Molmil
Highly biologically active insulin with additional disulfide bond
分子名称: Insulin, ZINC ION
著者Norrman, M, Vinther, T.N.
登録日2012-03-30
公開日2013-03-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Insulin analog with additional disulfide bond has increased stability and preserved activity.
Protein Sci., 22, 2013
4ZGM
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BU of 4zgm by Molmil
Crystal structure of Semaglutide peptide backbone in complex with the GLP-1 receptor extracellular domain
分子名称: 3,6,9,12,15,18-hexaoxahexacosan-1-ol, Glucagon-like peptide 1 receptor, Semaglutide peptide backbone; 8Aib,34R-GLP-1(7-37)-OH
著者Reedtz-Runge, S.
登録日2015-04-23
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.
J.Med.Chem., 58, 2015
2W44
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BU of 2w44 by Molmil
Structure DeltaA1-A4 insulin
分子名称: CHLORIDE ION, INSULIN, RESORCINOL, ...
著者Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H.
登録日2008-11-21
公開日2009-12-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform.
Biochemistry, 49, 2010
8RRP
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BU of 8rrp by Molmil
Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin
分子名称: ACETATE ION, Insulin, Insulin B chain
著者Schluckebier, G, Johansson, E.
登録日2024-01-23
公開日2024-07-10
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.
Nat Commun, 15, 2024
5BTS
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BU of 5bts by Molmil
Structural and biophysical characterization of a covalent insulin dimer formed during storage of neutral formulation of human insulin
分子名称: Insulin A chain, Insulin B chain
著者Norrman, M, Hjorth, C.F.
登録日2015-06-03
公開日2016-03-09
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
J.Pharm.Sci., 105, 2016
6S4J
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BU of 6s4j by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin
分子名称: IMIDAZOLE, Insulin, KUT [2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]
著者Johansson, E.
登録日2019-06-28
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
6S4I
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BU of 6s4i by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin
分子名称: Insulin, NITRATE ION
著者Johansson, E.
登録日2019-06-28
公開日2020-07-15
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
6S34
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BU of 6s34 by Molmil
Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution
分子名称: 1,2-ETHANEDIOL, Insulin A chain, Insulin B chain
著者Johansson, E.
登録日2019-06-24
公開日2019-07-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Zinc free, dimeric human insulin determined to 1.35 Angstrom resolution
Not Published

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件を2024-07-31に公開中

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