4ZRO
 
 | | 2.1 A X-Ray Structure of FIPV-3CLpro bound to covalent inhibitor | | 分子名称: | 3C-like proteinase, Bounded inhibitor of N-(tert-butoxycarbonyl)-L-seryl-L-valyl-N-{(2S)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-leucinamide, DIMETHYL SULFOXIDE | | 著者 | St John, S.E, Mesecar, A.D. | | 登録日 | 2015-05-12 | | 公開日 | 2015-10-14 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (2.0566 Å) | | 主引用文献 | X-ray structure and inhibition of the feline infectious peritonitis virus 3C-like protease: Structural implications for drug design.
Bioorg.Med.Chem.Lett., 25, 2015
|
|
4YO9
 | | HKU4 3CLpro unbound structure | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3C-like proteinase, ACETATE ION, ... | | 著者 | St John, S.E, Mesecar, A. | | 登録日 | 2015-03-11 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg.Med.Chem., 23, 2015
|
|
4YOJ
 | | HKU4 3CLpro bound to non-covalent inhibitor 2A | | 分子名称: | 3C-like proteinase, ACETATE ION, FORMIC ACID, ... | | 著者 | St John, S.E, Mesecar, A. | | 登録日 | 2015-03-11 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg.Med.Chem., 23, 2015
|
|
4YOG
 | | HKU4-3CLpro bound to non-covalent inhibitor 3B | | 分子名称: | 3C-like proteinase, ACETATE ION, N-[4-(acetylamino)phenyl]-2-(1H-benzotriazol-1-yl)-N-[(1R)-2-(tert-butylamino)-2-oxo-1-(thiophen-3-yl)ethyl]acetamide | | 著者 | St John, S.E, Mesecar, A. | | 登録日 | 2015-03-11 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg.Med.Chem., 23, 2015
|
|
4YOI
 | | Structure of HKU4 3CLpro bound to non-covalent inhibitor 1A | | 分子名称: | 3C-like proteinase, ACETATE ION, FORMIC ACID, ... | | 著者 | St John, S.E, Mesecar, A. | | 登録日 | 2015-03-11 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4-The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).
Bioorg.Med.Chem., 23, 2015
|
|
5HYO
 | |
4RSP
 | |
4YLU
 | |
