5T45
 
 | | Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP.BeFx form | | 分子名称: | 4-{[(2-chloro-3-fluorobenzyl)carbamoyl](methyl)amino}-3,4-dideoxy-5-O-(isoquinolin-3-ylcarbamoyl)-D-erythro-pentitol, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Sirigu, S, Planelles-Herrero, V.J, Hartman, J, Houdusse, A. | | 登録日 | 2016-08-29 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5M05
 | | Chicken smooth muscle myosin motor domain co-crystallized with the specific CK-571 inhibitor, MgADP form | | 分子名称: | 4-{[(2-chloro-3-fluorobenzyl)carbamoyl](methyl)amino}-3,4-dideoxy-5-O-(isoquinolin-3-ylcarbamoyl)-D-erythro-pentitol, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Sirigu, S, Hartman, J, Houdusse, A. | | 登録日 | 2016-10-03 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.675 Å) | | 主引用文献 | Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5HKG
 | | Total chemical synthesis, refolding and crystallographic structure of a fully active immunophilin: calstabin 2 (FKBP12.6). | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | | 著者 | Sirigu, S, Huet, T, Bacchi, M, Jullian, M, Fould, B, Ferry, G, Vuillard, L, Chavas, L, Puget, K, Nosjean, O, Boutin, J.A. | | 登録日 | 2016-01-14 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6).
Protein Sci., 25, 2016
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4XDG
 | | Crystal Structure of Quinone Reductase II in complex with 2-(4-aminophenyl)-5-methoxy-1-oxy-indol-3-one molecule | | 分子名称: | (2S)-2-(4-aminophenyl)-1-hydroxy-5-methoxy-1,2-dihydro-3H-indol-3-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | | 著者 | Sirigu, S, Nepveu, F, Vuillard, L, Ferry, G, Isabet, T, Thompson, A, Boutin, J.A. | | 登録日 | 2014-12-19 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives.
Molecules, 22, 2017
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4XDH
 | | Crystal Structure of Quinone Reductase II in complex with a 2-(4-methoxy-phenyl)-5-methoxy-indol-3-one molecule | | 分子名称: | 5-methoxy-2-(4-methoxyphenyl)-3H-indol-3-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | | 著者 | Sirigu, S, Nepveu, F, Vuillard, L, Ferry, G, Isabet, T, Thompson, A, Boutin, J.A. | | 登録日 | 2014-12-19 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives.
Molecules, 22, 2017
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5EJY
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6PL0
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP from Xanthomonas campestris in the Pr state bound to BV chromophore | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Sirigu, S, Klinke, S, Goldbaum, F, Chavas, L, Rinaldi, J, Bonomi, H.R. | | 登録日 | 2019-06-30 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.
Sci Adv, 7, 2021
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6NDO
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193N from Xanthomonas campestris | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Sirigu, S, Klinke, S, Rinaldi, J, Conforte, V, Malamud, F, Goldbaum, F.A, Chavas, L, Bonomi, H.R. | | 登録日 | 2018-12-14 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.58 Å) | | 主引用文献 | Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms.
Febs J., 288, 2021
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6NDP
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193Q from Xanthomonas campestris | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Sirigu, S, Klinke, S, Rinaldi, J, Conforte, V, Malamud, F, Goldbaum, F.A, Chavas, L, Bonomi, H.R. | | 登録日 | 2018-12-14 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | | 主引用文献 | Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms.
Febs J., 288, 2021
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5M24
 | | RARg mutant-S371E | | 分子名称: | (9cis)-retinoic acid, CHLORIDE ION, DODECYL-ALPHA-D-MALTOSIDE, ... | | 著者 | Rochel, N, Sirigu, S. | | 登録日 | 2016-10-11 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptor gamma.
PLoS ONE, 12, 2017
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5UYR
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant D199A from Xanthomonas campestris | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Klinke, S, Goldbaum, F.A, Bonomi, H.R. | | 登録日 | 2017-02-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms.
Febs J., 288, 2021
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7L5A
 | | Crystal structure of the photosensory module from Xanthomonas campestris bacteriophytochrome XccBphP in the Pfr state | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Antelo, G, Sanchez-Lamas, M, Klinke, S, Goldbaum, F.A, Rinaldi, J, Bonomi, H.R. | | 登録日 | 2020-12-21 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.
Sci Adv, 7, 2021
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7L59
 | | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP-G454E variant from Xanthomonas campestris in the Pfr state | | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | | 著者 | Otero, L.H, Antelo, G, Sanchez-Lamas, M, Klinke, S, Goldbaum, F.A, Rinaldi, J, Bonomi, H.R. | | 登録日 | 2020-12-21 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.
Sci Adv, 7, 2021
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8CI6
 | | PBP AccA from A. vitis S4 in complex with D-glucose-2-phosphate (G2P) | | 分子名称: | 2-O-phosphono-alpha-D-glucopyranose, 2-O-phosphono-beta-D-glucopyranose, ABC transporter substrate binding protein (Agrocinopine) | | 著者 | Morera, S, Vigouroux, A. | | 登録日 | 2023-02-08 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.199 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8C6Y
 | | PBP AccA from A. tumefaciens Bo542 in apoform 2 | | 分子名称: | 1,2-ETHANEDIOL, Agrocinopine utilization periplasmic binding protein AccA | | 著者 | Morera, S, Vigouroux, A, legrand, P. | | 登録日 | 2023-01-12 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8CB9
 | | PBP AccA from A. tumefaciens Bo542 in complex with D-Glucose-2-phosphate | | 分子名称: | 2-O-phosphono-alpha-D-glucopyranose, 2-O-phosphono-beta-D-glucopyranose, Agrocinopine utilization periplasmic binding protein AccA | | 著者 | Morera, S, Vigouroux, A. | | 登録日 | 2023-01-25 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8BHD
 | | N-terminal domain of Plasmodium berghei glutamyl-tRNA synthetase (Tbxo4 derivative crystal structure) | | 分子名称: | GLYCEROL, Glutamate--tRNA ligase, SULFATE ION, ... | | 著者 | Benas, P, Jaramillo Ponce, J.R, Legrand, P, Frugier, M, Sauter, C. | | 登録日 | 2022-10-31 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Solution X-ray scattering highlights discrepancies in Plasmodium multi-aminoacyl-tRNA synthetase complexes.
Protein Sci., 32, 2023
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5EJQ
 | | Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF1 domain, mutant 2 | | 分子名称: | GLUTAMIC ACID, GLYCINE, Myosin-I heavy chain, ... | | 著者 | Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. | | 登録日 | 2015-11-02 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EJS
 | | Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1 | | 分子名称: | Myosin-I heavy chain | | 著者 | Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. | | 登録日 | 2015-11-02 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EJR
 | | Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain | | 分子名称: | 1,2-ETHANEDIOL, Myosin-I heavy chain | | 著者 | Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Clause, J, Titus, M.A, Houdusse, A. | | 登録日 | 2015-11-02 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Myosin MyTH4-FERM structures highlight important principles of convergent evolution.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8CAY
 | | PBP AccA from A. tumefaciens Bo542 in complex with Agrocinopine D-like | | 分子名称: | Agrocinopine D-like (C2-C2 linked; with an alpha and beta-D-glucopyranose), Agrocinopine D-like (C2-C2 linked; with two alpha-D-glucopyranoses), Agrocinopine utilization periplasmic binding protein AccA, ... | | 著者 | Morera, S, Vigouroux, A, Siragu, S. | | 登録日 | 2023-01-24 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.626 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8C6U
 | | PBP AccA-G145YG440Q mutant from A. tumefaciens Bo542 in apoform 4 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Agrocinopine utilization periplasmic binding protein AccA, ... | | 著者 | Morera, S, Vigouroux, A, Legrand, P. | | 登録日 | 2023-01-12 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.843 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8CH3
 | | PBP AccA from A. vitis S4 in complex with Agrocinopine C-like | | 分子名称: | 2-O-phosphono-alpha-D-glucopyranose, Agrocinopine utilization periplasmic binding protein AccA, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Morera, S, Vigouroux, A. | | 登録日 | 2023-02-06 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8C75
 | | PBP AccA from A. tumefaciens Bo542 in apoform 3 | | 分子名称: | 1,2-ETHANEDIOL, Agrocinopine utilization periplasmic binding protein AccA, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Morera, S, Vigouroux, A, Legrand, P. | | 登録日 | 2023-01-12 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.673 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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8CJU
 | | PBP AccA from A. vitis S4 in complex with agrocin84 | | 分子名称: | ABC transporter substrate binding protein (Agrocinopine), [(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl]oxy-N-[9-[(2R,3S,5R)-5-[[[(2R,3S)-4-methyl-2,3-bis(oxidanyl)pentanoyl]amino]-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]purin-6-yl]phosphonamidic acid | | 著者 | Morera, S, Vigouroux, A. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.349 Å) | | 主引用文献 | A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity.
Biochem.J., 481, 2024
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