6YVA
 
 | | PLpro-C111S with mISG15 | | 分子名称: | Replicase polyprotein 1a, Ubiquitin-like protein ISG15, ZINC ION | | 著者 | Shin, D, Dikic, I. | | 登録日 | 2020-04-28 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Nature, 587, 2020
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6YK8
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8GOK
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2O5K
 | | Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor | | 分子名称: | 2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE, Glycogen synthase kinase-3 beta | | 著者 | Shin, D, Lee, S.C, Heo, Y.S, Cho, Y.S, Kim, Y.E, Hyun, Y.L, Cho, J.M, Lee, Y.S, Ro, S. | | 登録日 | 2006-12-06 | | 公開日 | 2007-10-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta
Bioorg.Med.Chem.Lett., 17, 2007
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4ZQS
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3JRW
 | | Phosphorylated BC domain of ACC2 | | 分子名称: | Acetyl-CoA carboxylase 2 | | 著者 | Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. | | 登録日 | 2009-09-09 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK
Biochem.Biophys.Res.Commun., 391, 2010
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3JRX
 | | Crystal structure of the BC domain of ACC2 in complex with soraphen A | | 分子名称: | Acetyl-CoA carboxylase 2, SORAPHEN A | | 著者 | Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. | | 登録日 | 2009-09-09 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK.
Biochem.Biophys.Res.Commun., 391, 2010
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4LFU
 | | Crystal structure of Escherichia coli SdiA in the space group C2 | | 分子名称: | CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL | | 著者 | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | | 登録日 | 2013-06-27 | | 公開日 | 2014-03-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
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4LGW
 | | Crystal structure of Escherichia coli SdiA in the space group P6522 | | 分子名称: | GLYCEROL, Regulatory protein SdiA | | 著者 | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | | 登録日 | 2013-06-28 | | 公開日 | 2014-03-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
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2HJW
 | | Crystal Structure of the BC domain of ACC2 | | 分子名称: | Acetyl-CoA carboxylase 2 | | 著者 | Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. | | 登録日 | 2006-07-02 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
Proteins, 70, 2008
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6RYB
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6RYA
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6G0C
 | | Crystal structure of SdeA catalytic core | | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Ubiquitinating/deubiquitinating enzyme SdeA | | 著者 | Kalayil, S, Bhogaraju, S, Basquin, J, Dikic, I. | | 登録日 | 2018-03-17 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Nature, 557, 2018
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6ZQH
 | | Yeast Uba1 in complex with ubiquitin | | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ... | | 著者 | Misra, M, Schindelin, H. | | 登録日 | 2020-07-09 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | | 主引用文献 | Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.
Chemistry, 27, 2021
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5ZU1
 | | Crystal Structure of BZ junction in diverse sequence | | 分子名称: | DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*AP*GP*GP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*CP*TP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase | | 著者 | Kim, K.K, Kim, D. | | 登録日 | 2018-05-05 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.009 Å) | | 主引用文献 | Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
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5ZUO
 | | Crystal Structure of BZ junction in diverse sequence | | 分子名称: | DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*CP*GP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase | | 著者 | Kim, K.K, Kim, D. | | 登録日 | 2018-05-08 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | | 主引用文献 | Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
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5ZUP
 | | Crystal Structure of BZ junction in diverse sequence | | 分子名称: | (5'-D(*AP*CP*GP*GP*TP*TP*TP*AP*TP*CP*GP*CP*GP*CP*GP*CP*G)-3'), (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*CP*AP*AP*TP*AP*AP*AP*CP*C)-3'), Double-stranded RNA-specific adenosine deaminase | | 著者 | Kim, K.K, Kim, D. | | 登録日 | 2018-05-08 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Sequence preference and structural heterogeneity of BZ junctions.
Nucleic Acids Res., 46, 2018
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4Q9D
 | | X-ray structure of a putative thiamin diphosphate-dependent enzyme isolated from Mycobacterium smegmatis | | 分子名称: | Benzoylformate decarboxylase, FORMIC ACID, MAGNESIUM ION | | 著者 | Andrews, F.H, Horton, J.D, Yoon, H.J, Malik, A.M.K, Logsdon, M.G, Shin, D.H, Kneen, M.M, Suh, S.W, McLeish, M.J. | | 登録日 | 2014-04-30 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The kinetic characterization and X-ray structure of a putative benzoylformate decarboxylase from M. smegmatis highlights the difficulties in the functional annotation of ThDP-dependent enzymes.
Biochim.Biophys.Acta, 1854, 2015
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6TU9
 | | The ROR1 Pseudokinase Domain Bound To Ponatinib | | 分子名称: | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Inactive tyrosine-protein kinase transmembrane receptor ROR1 | | 著者 | Mathea, S, Preuss, F, Chatterjee, D, Niininen, W, Ungureanu, D, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S. | | 登録日 | 2020-01-04 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Mol.Cell, 79, 2020
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6S5T
 | | Legionella pneumophila SidJ-Human calmodulin complex | | 分子名称: | Calmodulin-2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SidJ | | 著者 | Bhogaraju, S, Galej, W.P, Pfleiderer, M.M, Adams, M. | | 登録日 | 2019-07-02 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation.
Nature, 572, 2019
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6TUA
 | | The RYK Pseudokinase Domain | | 分子名称: | SULFATE ION, Tyrosine-protein kinase RYK | | 著者 | Mathea, S, Chatterjee, D, Preuss, F, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S. | | 登録日 | 2020-01-04 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Mol.Cell, 79, 2020
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4KMF
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1L8O
 | | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase | | 分子名称: | L-3-phosphoserine phosphatase, PHOSPHATE ION, SERINE | | 著者 | Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y. | | 登録日 | 2002-03-21 | | 公開日 | 2003-04-01 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
J.Biol.Chem., 277, 2002
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1L8L
 | | Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase | | 分子名称: | D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID, L-3-phosphoserine phosphatase | | 著者 | Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y. | | 登録日 | 2002-03-21 | | 公開日 | 2003-04-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
J.Biol.Chem., 277, 2002
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6ICI
 | | Crystal structure of human MICAL3 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3 | | 著者 | Hwang, K.Y, Kim, J.S. | | 登録日 | 2018-09-06 | | 公開日 | 2020-03-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3.
Iucrj, 7, 2020
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