6VJM
| Human metabotropic GABA(B) receptor in its apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shaye, H, Han, G.W, Gati, C, Cherezov, V. | 登録日 | 2020-01-16 | 公開日 | 2020-06-10 | 最終更新日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Structural basis of the activation of a metabotropic GABA receptor. Nature, 584, 2020
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6UO8
| Human metabotropic GABA(B) receptor bound to agonist SKF97541 and positive allosteric modulator GS39783 | 分子名称: | (R)-(3-aminopropyl)methylphosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shaye, H, Han, G.W, Gati, C, Cherezov, V. | 登録日 | 2019-10-14 | 公開日 | 2020-06-10 | 最終更新日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Structural basis of the activation of a metabotropic GABA receptor. Nature, 584, 2020
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6UOA
| Human metabotropic GABA(B) receptor in its intermediate state 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, ... | 著者 | Shaye, H, Han, G.W, Gati, C, Cherezov, V. | 登録日 | 2019-10-14 | 公開日 | 2020-06-10 | 最終更新日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Structural basis of the activation of a metabotropic GABA receptor. Nature, 584, 2020
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6UO9
| Human metabotropic GABA(B) receptor bound to agonist SKF97541 in its intermediate state 2 | 分子名称: | (R)-(3-aminopropyl)methylphosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shaye, H, Han, G.W, Gati, C, Cherezov, V. | 登録日 | 2019-10-14 | 公開日 | 2020-06-10 | 最終更新日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural basis of the activation of a metabotropic GABA receptor. Nature, 584, 2020
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7SK2
| Human wildtype GABA reuptake transporter 1 in complex with tiagabine, inward-open conformation | 分子名称: | Sodium- and chloride-dependent GABA transporter 1, Tiagabine | 著者 | Gati, C, Motiwala, Z, Aduri, N.G, Shaye, H, Han, G.W, Cherezov, V. | 登録日 | 2021-10-19 | 公開日 | 2022-06-08 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | 主引用文献 | Structural basis of GABA reuptake inhibition. Nature, 606, 2022
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7JNI
| Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, HEXANE-1,6-DIOL, ... | 著者 | Cherezov, V, Shaye, H, Han, G.W. | 登録日 | 2020-08-04 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma. Proc.Natl.Acad.Sci.USA, 119, 2022
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